3 excluded
• Used partial denture n= 1
• Used antibiotics n= 1
• Diabetes n= 1
123 subjects screened120 subjects randomized
Failed to follow up
n= 2 Failed to follow upn= 3
Failed to follow up n = 2 Loss of taste sensation
n= 1 40 subjects in the positive control group 40 subjects in
the test group negative control group 40 subjects in the
Rosing CK et al.
Baseline Week 4 Week 6
0 1 2 3 4 5
A A A
B C
D
B C
D
M
ea
n
Pl
aq
ue
in
de
x
0.0 0.5 1.0 1.5
A A A
B B C B B C M ea n Pl aq ue S ev eri ty
Baseline Week 4 Week 6
Test Positive Control Negative Control
Baseline Week 4 Week 6
Test Positive Control Negative Control
0.0 0.2 0.4 0.6 0.8 1.0
A A A
B C D B C D M ea n G in gi va l Se ve rit y 0.0 0.5 1.0 1.5 2.0
A A A
B C D B C D M ea n G in gi va l I nd ex
Baseline Week 4 Week 6
Rosing CK et al.
Baseline Week 4 Week 6
Test Positive Control Negative Control
0 1 2 3 4 5
A A A
B C D B C D M ea n Pl aq ue In te rp ro xim al
Baseline Week 4 Week 6
Test Positive Control Negative Control
0.0 0.5 1.0 1.5
2.0 A A A
Rosing CK et al.
.
