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Fibroblast growth factors as tissue repair and regeneration therapeutics

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Academic year: 2017

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Figure 1 Phylogenetic relationship of the FGFs based on amino acid sequence. According to amino acid sequence, dendroscope was used to show that FGF family is divided into seven subfamilies.
Figure 2 Schematic diagram of the core structure unit of the beta-trefoil. PDB ID: 2FGF (Zhang et al., 1991)
Figure 3 FGF interactions with FGFR and heparin/heparan sulfate. (A) Ternary structure of FGF-FGFR-heparin complex (1FQ9 (Schlessinger et al., 2000))
Figure 4 Structures of disaccharide units of HS and heparin. (A) Structure of disaccharide unit of heparin/HS
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