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Angiotensin II (Ang II)

Alternative pathways for angiotensin II generation in the cardiovascular system

Alternative pathways for angiotensin II generation in the cardiovascular system

... (RAS), angiotensin II (Ang II), plays a key role in regulating cardiovascular homeostasis, acting both on the regulation of blood volume and peripheral vascular resistance ...recognized. ...

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Steroidogenic enzymes mRNA expression profile and steroids production in bovine theca cells cultured in vitro and stimulated with angiotensin II

Steroidogenic enzymes mRNA expression profile and steroids production in bovine theca cells cultured in vitro and stimulated with angiotensin II

... Renin Angiotensin System (RAS) with steroidogenesis since 1995, when it was first demonstrated that angiotensin II (Ang II) could act on steroid production in both theca and granulosa cells of ...

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Sex differences in angiotensin II- induced hypertension

Sex differences in angiotensin II- induced hypertension

... of angiotensin II (ANG II) via interactions with free radicals and nitric oxide, generating path- ways within brain circumventricular organs and in central sympatho- modulatory ...ANG II ...

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INHIBITION OF CENTRAL ANGIOTENSIN II-INDUCED PRESSOR RESPONSES BY HYDROGEN PEROXIDE

INHIBITION OF CENTRAL ANGIOTENSIN II-INDUCED PRESSOR RESPONSES BY HYDROGEN PEROXIDE

... Angiotensin II (ANG II), the main peptide released by the activation of the renin-angiotensin system, acts cen- trally to produce pressor responses dependent on sympa- thetic activation and ...

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Sonic hedgehog carried by microparticles corrects angiotensin II-induced hypertension and endothelial dysfunction in mice.

Sonic hedgehog carried by microparticles corrects angiotensin II-induced hypertension and endothelial dysfunction in mice.

... abolished angiotensin II (Ang II)-induced ...Ang II, the arrows indicate the time at which the mice received MPs Shh+ or vehicle by ...

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Role of endothelium in angiotensin II formation by the rat aorta and mesenteric arterial bed

Role of endothelium in angiotensin II formation by the rat aorta and mesenteric arterial bed

... the angiotensin II (Ang II)-generating system by analyzing the vasoconstrictor effect of Ang II, angiotensin I (Ang I), and tetradecapeptide (TDP) renin substrate in the absence and ...

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Anti-Plasmodium Activity of Angiotensin II and Related Synthetic Peptides

Anti-Plasmodium Activity of Angiotensin II and Related Synthetic Peptides

... ang II In addition to applications of VC5 and ang II to target sporozoites in the vector mosquitoes, these peptides also could be useful to block parasite development in vertebrate ...hosts. ...

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Recent advances in angiotensin II signaling

Recent advances in angiotensin II signaling

... Angiotensin II (Ang II) regulates blood pressure, plasma volume, sympathetic ner- vous activity and thirst ...Ang II is produced sys- temically via the classical renin-angiotensin ...

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Vascular mechanisms involved in angiotensin II-induced venoconstriction in hypertensive rats

Vascular mechanisms involved in angiotensin II-induced venoconstriction in hypertensive rats

... of angiotensin II (Ang II) in spontaneously hypertensive rats (SHR), we used preparations of mesenteric venular beds and the circular muscle of the portal ...Ang II in the presence or absence ...

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Folic acid mitigates angiotensin-II-induced blood pressure and renal remodeling.

Folic acid mitigates angiotensin-II-induced blood pressure and renal remodeling.

... Angiotensin II has multiple effects on the ...Ang II induced activation of prostaglandin EP3 receptor(s) was found to elevate blood pressure [51] and the lack of microsomal prostaglandin E synthase-1 ...

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The Effect of Losartan on Angiotensin II-Induced Cell Proliferation in a Rat Aorta Smooth Muscle Cell Line

The Effect of Losartan on Angiotensin II-Induced Cell Proliferation in a Rat Aorta Smooth Muscle Cell Line

... and Kumar 2006). In contrast, other studies have suggested that losartan, after AT1 receptor binding and internalization, blocks intracellular angiotensin II action (Cook et al. 2001). This controversy has ...

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Ligand-induced endocytosis and nuclear localization of angiotensin II receptors expressed in CHO cells

Ligand-induced endocytosis and nuclear localization of angiotensin II receptors expressed in CHO cells

... that angiotensin II, besides its better known ef- fect on plasma membrane receptors trigger- ing second-messenger cascades, may be transported to the nucleus, where it may interact directly with receptors ...

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Biological and conformational evaluation of angiotensin II lactam bridge containing analogues

Biological and conformational evaluation of angiotensin II lactam bridge containing analogues

... In water, the CD spectrum of analogue 8 presents a negative minimum near 200 nm that is shifted to 225 nm when SDS, TFE or MeOH is added. This minimum, together with the presence of a positive maximum near 200 nm, ...

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Angiotensin II facilitates breast cancer cell migration and metastasis.

Angiotensin II facilitates breast cancer cell migration and metastasis.

... whether angiotensin II, a major vasoactive peptide both produced locally and released in the bloodstream, may trigger activating signals that contribute to cancer cell extravasation and ...that ...

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Evaluation of renin and angiotensin II levels in pseudoexfoliation syndrome

Evaluation of renin and angiotensin II levels in pseudoexfoliation syndrome

... and angiotensin II levels were analyzed by ...plasma angiotensin II, or aqueous humor angiotensin II ...humor angiotensin II levels were examined separately for ...

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The role of angiotensin II and TGF-beta on the progression of chronic allograft nephropathy

The role of angiotensin II and TGF-beta on the progression of chronic allograft nephropathy

... 5. Bennett WM, DeMattos A, Mayer MM, Andoh T, Barry JM. Chronic cyclosporine nephropathy: the Achilles’ heel of immunosuppressive therapy. Kidney Int 1996;50:1089. 6. Shihab FS, Bennett WM,Tanner AM,Andoh TF. ...

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Angiotensin II Inhibits Insulin Binding to Endothelial Cells

Angiotensin II Inhibits Insulin Binding to Endothelial Cells

... whether angiotensin II (ATII), which is a known substance involved in the increase in insulin resistance, inhibits insulin binding on bovine aortic endothelial cells ...

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Endogenous angiotensin II modulates nNOS expression in renovascular hypertension

Endogenous angiotensin II modulates nNOS expression in renovascular hypertension

... Ang II-infused rats did not present improvement of renal func- tion in the study by these investigators ...Ang II for 14 days and reduced in DOCA-salt hypertensive rats, a model of low Ang II ...

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Dissociation between the circulating renin-angiotensin system and angiotensin II receptors in central losartan-induced hypertension

Dissociation between the circulating renin-angiotensin system and angiotensin II receptors in central losartan-induced hypertension

... mg/kg), losartan, an AT 1 ANG II receptor antagonist (1.25, 2.5, 5.0 and 10.0 mg/kg), captopril, an angiotensin-converting enzyme (ACE) blocker (10 mg/kg), or 0.9% saline was injected intravenously (iv) 20 ...

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Does protein binding modulate the effect of angiotensin II receptor antagonists?

Does protein binding modulate the effect of angiotensin II receptor antagonists?

... hand, the estimation of protein binding is not straightforward; thus a clear discrimination between 99 and 99.5 or 99.9% binding cannot be established precisely by conventional methods, such as ultrafil- tration or ...

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