Candidate gene Association Studies
The genetics of canine periodontal disease: a candidate gene approach
... several studies providing a numerical estimate of the overall effect of ...primary studies (Trikalinos et ...putative gene–disease ...such association may be obtained, in addition to offering ...
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Examining ERBB2 as a candidate gene for susceptibility to leprosy (Hansen’s disease) in Brazil
... Subjects and study design - The primary cohort was comprised of 72 multicase leprosy families (372 individ- uals) (Table I) identified from medical records at local Ministry of Health centres in Belém, state of Pará ...
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An evolutionary framework for association testing in resequencing studies.
... Description of dataset. About 3500 prospectively sampled individuals from the population in Dallas, Texas, were sequenced at a candidate gene for dyslipidemia: ANGPTL4 (Ensembl Acc:16039). These individuals ...
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A genetic predictive model for canine hip dysplasia: integration of Genome Wide Association Study (GWAS) and candidate gene approaches.
... potential candidate genes involved in ...CHST3 gene, just 14 bp upstream the initial ATG start ...CHST3 gene have been previously found as associated with spondyloepiphyseal dysplasia in humans, ...
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META-GSA: Combining Findings from Gene-Set Analyses across Several Genome-Wide Association Studies.
... a gene set of interest to all other genes. If the investigated gene set is truly dominated by other, containing more strongly associ- ated genes, the simulation revealed META-GSA as performing poorly, ...
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Rrp1b, a new candidate susceptibility gene for breast cancer progression and metastasis.
... however, studies in larger populations are required to better define the relative effect of the variant allele on outcome markers in breast ...the association between the 1421G!A SNP and breast cancer ...
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Social cognitive role of schizophrenia candidate gene GABRB2.
... the gene product on population ...the association of GABRB2 with psychosis and altruism, respectively representing psychiatric and psychological facets of social ...significant association was ...
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Population-specific haplotype association of the postsynaptic density gene DLG4 with schizophrenia, in family-based association studies.
... from candidate genes, based on tagging ...Future studies should focus on dense screening in selected haplotype ...control association analysis of the DLG4 in Japanese schizophrenia ...
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Candidate genes detected in transcriptome studies are strongly dependent on genetic background.
... of candidate genes generated from full genome transcriptomic studies, we expect a high degree of overlap between traits in common genetic ...evolutionary studies (see also) ...future studies ...
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Genome-Wide Association Studies of the Human Gut Microbiota.
... This gene was implicated in a previous GWAS of body mass index (BMI) in African Americans, because a SNP associated with BMI is located near the ...this gene acts to influence ...novo candidate ...
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Association of transcription factor gene LMX1B with autism.
... Linkage, candidate gene and whole genome association studies have suggested several genes and chromosomal regions associated with the ...potential candidate genes associated with the ...
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Genome association study through nonlinear mixed models revealed new candidate
... genome association anal- yses is an unbiased search of the entire genome without any assumptions about the role of a certain gene, the candidate gene approach allows researchers to investi- ...
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Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action.
... MODY1 gene) encodes an orphan hormone nuclear receptor that, together with TCF1 (LocusLink ID 6927), encoding HNF1a, TCF2 (LocusLink ID 6928), encoding HNF1b, and FOXA2 (LocusLink ID 3170), encoding HNF3b, ...
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Association of candidate gene expression with intramuscular fat content in the porcine Longissimus dorsi muscle
... There have been numerous studies comparing sensory characteristics of different pig breeds. Intramuscular fat content is an important factor that influences sensory quality Klont et al., . The amount of visible ...
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Identification of MAMDC1 as a candidate susceptibility gene for systemic lupus erythematosus (SLE).
... previous studies [16,17] genotyping data were thus available in this initial step for 47 MS markers and 17 SNPs, corresponding to an average marker distance of 350 kilo bases (kb) in the ...of association ...
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Gene networks from genome wide association studies for pigs reproductive traits
... SNP association studies that consider continuous phenotypes under Gaussian assumptions, this trait is characterized as discrete variable, which could potentially follow other distributions, such as the ...
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Association study of candidate gene polymorphisms with amnestic mild cognitive impairment in a Chinese population.
... of studies point out that cholesterol is involved in Ab generation ...and candidate gene polymorphisms in a Chinese population by reporting single gene analyses in the four main pathways ...
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Validating genome association studies for meat quality and carcass traits in pigs through gene networks and meta-analysis
... These variations, which are the most frequent type found in DNA, are called SNPs and they are valuable markers for high-throughput genetic mapping, genetic variation studies and association mapping. SNPs ...
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Association of a serotonin transporter gene ( SLC6A4 ) 5-HTTLPR
... between genetic and environmental factors (Knowler et al., 1993). In the search for genetic factors that confer suscepti- bility to obesity and T2DM, several candidate genes have been identified (Prokopenko et ...
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Identification and candidate gene analysis of a novel phytophthora resistance gene Rps10 in a Chinese soybean cultivar.
... rxp gene and several QTLs conferring bacterial leaf pustule resistance are also located at different regions of chromosome 17 ...resistance gene identified on chromosome 17 that confers resistance to ...
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