cell cycle arrest
Cell cycle arrest and cell survival induce reverse trends of cardiolipin remodeling.
... promote cell-cycle arrest during DNA damage and aberrant growth factor signaling ...in cell viability, confirming the essential requirement for p53 in nutrient-dependent ...
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MiR-107 and MiR-185 can induce cell cycle arrest in human non small cell lung cancer cell lines.
... the cell cycle regulation (Table ...for cell cycle regulation by these ...causes cell cycle arrest in liver cancer cell lines ...in cell cycle ...
9
2-Methyl 2-butanol suppresses human retinoblastoma cells through cell cycle arrest and autophagy
... HXO-RB44 cell death but is cytotoxic to normal cells at higher ...a cell cycle inhibitory protein, which plays an important role in cell cycle regulation whereas cyclin-B1 is a ...
7
Middle infrared radiation induces G2/M cell cycle arrest in A549 lung cancer cells.
... regulating cell shape [17,18], and both actin filaments and microtubules are known to affect the formation and distribution of cell focal adhesions [17] which determine cell morphology and ...the ...
9
Nucleolin down-regulation is involved in ADP-induced cell cycle arrest in S phase and cell apoptosis in vascular endothelial cells.
... various cell compart- ments, especially in the nucleolus, of which it is a major component and functions as a prominent RNA-binding protein (RBP) to interacts with precursor ribosomal (r)RNA and is essential for ...
12
CMTM3 inhibits human testicular cancer cell growth through inducing cell-cycle arrest and apoptosis.
... cancer cell lines and tumor tissues but highly expressed in normal testis ...G2 cell cycle arrest and ...G2 cell cycle arrest and ...
11
AZD2014 Radiosensitizes Oral Squamous Cell Carcinoma by Inhibiting AKT/mTOR Axis and Inducing G1/G2/M Cell Cycle Arrest.
... controls cell cycle progression and cell proliferation by regulat- ing S6K1 and the eukaryotic translation initiation factor, ...cause cell cycle arrest [11,12], we assessed ...
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Pravastatin induces cell cycle arrest and decreased production of VEGF and bFGF in multiple myeloma cell line
... B cell bone marrow neoplasia characterized by inflammation with an intense secretion of growth factors that promote tumor growth, cell survival, migration and ...MM cell line.Cell cycle and ...
7
Effects of hormone agonists on Sf9 cells, proliferation and cell cycle arrest.
... Growth and development are controlled by two major hormones in insects, the steroid 20-hydroxyecdysone (20E) and the sesquiterpenoid juvenile hormone (JH) [1]. The cross-talk between these two hormones regulates all ...
9
PVMMA-shelled selol nanocapsules promote cell cycle arrest in A549 lung adenocarcinoma cells
... the viability of human lung adenocarcinoma (A549) cells were observed after exposure to SPN or free Selol (S) at concentrations of 50 μg/mL for 72 h and 100 and 150 μg/mL for 48 and 72 h (p < 0.05). In contrast, ...
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Fluoroquinolone-mediated inhibition of cell growth, S-G2/M cell cycle arrest, and apoptosis in canine osteosarcoma cell lines.
... In order to further confirm that FQ’s were capable of inducing apoptosis we performed Western blot analysis of PARP cleavage Figure 1. The inhibitory effects of CPFX or ENFX on cell proliferation and colony ...
6
Ran GTPase-activating protein 1 is a therapeutic target in diffuse large B-cell lymphoma.
... LBCL cell lines ...of cell-cycle regulators ...or cell-cycle deregulation ...tumor cell death and cell-cycle arrest but showed no effect on LCL ...
12
A comparison of Ku0063794, a dual mTORC1 and mTORC2 inhibitor, and temsirolimus in preclinical renal cell carcinoma models.
... renal cell carcinoma ...of cell metabolism, growth and ...RCC cell lines, Caki-1 and 786-O, in vitro by inducing cell cycle arrest and autophagy, but not ...
12
Geminin is required for zygotic gene expression at the Xenopus mid-blastula transition.
... It has recently been reported that Geminin knockdown enhances the expression of some embryonic genes as much as 10-fold [35]. We tested the expression of four of the most highly induced genes: Epiker, Msx1b, ID2, and ...
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Growth inhibitory effect and Chk1-dependent signaling involved in G M arrest on human gastric cancer cells induced by diallyl
... induces cell cycle G 2 /M arrest in human gastric cancer MGC803 ...and cell cycle arrest in human gastric cancer BGC823 ...of cell cycle redistribution in ...
9
Aciculatin induces p53-dependent apoptosis via MDM2 depletion in human cancer cells in vitro and in vivo.
... induces cell death in human cancer cells and HCT116 mouse xenografts due to G1 arrest and subsequent ...for cell cycle arrest and cell death was p53 accumulation followed by ...
10
Prevention of radiation-induced salivary gland dysfunction utilizing a CDK inhibitor in a mouse model.
... to cell death or cell cycle arrest and DNA ...mediated cell cycle arrest following radiation is ...toward cell cycle arrest rather than ...
10
Effects of gamma-radiation on cell growth, cycle arrest, death, and superoxide dismutase expression by DU 145 human prostate cancer cells
... apoptotic cell death plays an important role ...apoptotic cell death as an end point, was observed for well-differentiated tumors ...IR-induced cell killing, other clinically important effects of IR ...
10
Non-steroidal anti-inflammatory drugs decrease E2F1 expression and inhibit cell growth in ovarian cancer cells.
... cancer cell growth, we wanted to determine whether this decrease was due to alterations in the cell ...induced cell cycle arrest in all 3 ovarian cancer cell lines examined, as ...
9
Anticancer activity of lichen substances: a systematic review
... cancer cell lines was highly improved by usnic acid benzylidene ...with cell cycle arrest at G0/G1, G2/M and S phases (Bačkorová et ...apoptotic cell death shown by the depolarization ...
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