E-selectin
A variant in the ABO gene explains the variation in soluble E-selectin levels-results from dense genotyping in two independent populations.
... Methodology/ Principal Findings: Data of the present study was drawn from the population-based MONICA/KORA Augsburg study (n = 1,482) and the patients-based LURIC study (n = 1,546). A high-density genotyping array (50K ...
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E-selectin gene polymorphisms and essential hypertension in Asian population: an updated meta-analysis.
... E- selectin A561C and C1839T polymorphisms might be associated with inflammation related diseases, such as severe atherosclerosis, CHD and some type of IS ...E- selectin gene polymorphisms (A561C and ...
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Phase 1 study of the E-selectin inhibitor GMI 1070 in patients with sickle cell anemia.
... E- selectin; soluble ICAM-1); monocyte activation (PMA); and coagulation system activation (tissue factor and thrombin-anti- thrombin complexes) were serially ...
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Correlation between serum E-selectin levels and panoramic nailfold capillaroscopy in systemic sclerosis
... E-selectin range was 38 to 200 ng/ml (mean = 80 ± 39.94) and disease duration was 64.94 ± 61.57 months. We observed correlation between serum E-selectin levels and the deletion score capillaroscopic pa- ...
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Serum and cerebrospinal fluid concentrations of E-selectin in patients with aneurysmal subarachnoid hemorrhage
... The selectin family of CAMs consists of three members, P-, E-, and L-selectins, all of which mediate rolling of leukocytes along the VE, the early step of the inflammatory process ...E- selectin whose ...
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TWEAK enhances E-selectin and ICAM-1 expression, and may contribute to the development of cutaneous vasculitis.
... CV comprises a wide spectrum of diseases that affect the blood vessels of the skin. Despite the different causes such as vascular deposition of immune complexes or activation by infection, the Figure 9. TWEAK activates ...
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Repositório Institucional da UFPA: Circulating early biomarkers of atherogenesis in participants of the Longitudinal Study of Adult Health (ELSA-Brasil) without diabetes or cardiovascular disease
... Attempts to improve the prediction of cardiovascular events have motivated investigations into biomarkers involved in the early atherosclerotic process. Ageing is a major risk factor for atherosclerosis, and its ...
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Int. braz j urol. vol.37 número5
... with a higher rate in hormone-refractory phase, with a relevant importance in PCa progression (14). Tu- morogenesis and progression are characterized by changed expression of cell adhesion molecules that are ...
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Arq. Bras. Cardiol. vol.87 número4
... 17. Tenaglia AN, Buda AJ, Wilkins RG, Barron MK, Jeffords PR, VO K, et al. Levels of expression of P-selectin, E-selectin, and intercellular adhesion molecule-1 in coronary atherectomy specimens from ...
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Babesia bovis: expression of adhesion molecules in bovine umbilical endothelial cells stimulated with plasma from infected cattle
... sitized with pathogenic sample of Babesia bovis (passage 7 BboUFV-1), for the subsequent “ex vivo” determination of the expression of adhesion molecules. Five non-inoculated ani- mals (group B) were used as the negative ...
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The Effects of NF-κB and c-Jun/AP-1 on the Expression of Prothrombotic and Proinflammatory Molecules Induced by Anti-β2GPI in Mouse.
... Thrombosis is a devastating consequence and the most prominent clinical manifestation in APS, which may affect any organ in the body [39]. Nonetheless, the induction of an endothelial proinflammation and procoagulation ...
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The shedding of CD62L (L-selectin) regulates the acquisition of lytic activity in human tumor reactive T lymphocytes.
... The trafficking of leukocytes from the peripheral blood to the surrounding tissue is pivotal for inflammatory responses and is tightly regulated by cell adhesion molecules on T lymphocytes and endothelial cells [1]. The ...
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Relationship between deep venous thrombosis and inflammatory cytokines in postoperative patients with malignant abdominal tumors
... Enzyme-linked immunosorbent assay (ELISA) kits for human serum C-reactive protein (CRP), interleukin-6 (IL-6) and IL-10 were purchased from Calvin Biological Technology Co., Ltd., China. ELISA kits for human serum ...
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West Nile virus-induced cell adhesion molecules on human brain microvascular endothelial cells regulate leukocyte adhesion and modulate permeability of the in vitro blood-brain barrier model.
... Characterizing the mechanisms by which West Nile virus (WNV) causes blood-brain barrier (BBB) disruption, leukocyte infiltration into the brain and neuroinflammation is important to understand the pathogenesis of WNV ...
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Alpha-linolenic acid exerts an endothelial protective effect against high glucose injury via PI3K/Akt pathway.
... Cardiovascular disease is one of the leading causes of death in the western world and diabetes mellitus has been identified as a primary risk factor [1]. Endothelial inflammation and dysfunction play important roles in ...
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P-selectin, carcinoma metastasis and heparin: novel mechanistic connections with therapeutic implications
... The roles of the other two selectins also need to be explored further. Under the con- ditions we used for our studies, E-selectin would not have been expressed. Since hepa- rin also inhibits L-selectin ...
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Renata Adrielle Lima Vieira1 , Renata Nascimento de Freitas2 and Ana Carolina Pinheiro Volp3
... All molecules reviewed here relate positively with an anthropometric marker as BMI, WC, WHR, but studies also show that there is no relation of ICAM-1 with BMI after adjustment for age, sex, smoking status and ethnicity, ...
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Clinics vol.70 número3
... pathogenesis of atherosclerosis. MIF is a pro-inflammatory regulator of many acute and chronic inflammatory diseases (4–7). During events such as acute myocardial infarction (AMI), both hypoxia and oxidative stress ...
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Structural features of PSGL-1 required for binding to P-selectin
... PSGL-1/L- selectin interactions in neutrophil-neutrophil interactions as a way of amplifying the initial leukocyte accumulation that is dependent on P-selectin ...L- selectin and may contribute to ...
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Renato Linhares de Assis Ademar Ribeiro Romeiro RESUMO
... Discute-se como surgiram movimentos de agricultura alternativa ao modelo da atualmente chamada agricultura moderna, e como estes foram progressivamente se apresentando como opção de sust[r] ...
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