Epidermal Growth Factor (EGF)
Active synthesis of epidermal growth factor in human mammary glands
... Epidermal growth factor (EGF) and insulin-like growth factor-1 (IGF-1) are trophic peptides present in human ...These growth factors stimulate the growth, differentia- ...
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Nitric oxide from inflammatory origin impairs neural stem cell proliferation by inhibiting epidermal growth factor receptor signaling
... fibroblast growth factor; BSA, bovine serum albu- min; BrdU, 5-bromo-2 -deoxyuridine; NOC-18, DETA-NONOate; DIV, days in vitro; EdU, 5-ethynyl-2 -deoxyuridine; EGF, epidermal growth ...
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Expression of epidermal growth factor receptor (EGFR) in cholangiocarcinomas: predictive factors and survival
... Epidermal growth factor receptor (EGFR) is a cell membrane receptor tyrosine kinase encoded by ...as epidermal growth factor (EGF), heparin binding factor (HB-EGF), and ...
9
Internalization mechanisms of the epidermal growth factor receptor after activation with different ligands.
... The epidermal growth factor receptor (EGFR) regulates normal growth and differentiation, but dysregulation of the receptor or one of the EGFR ligands is involved in the pathogenesis of many ...
12
Chemical genomic-based pathway analyses for epidermal growth factor-mediated signaling in migrating cancer cells.
... the epidermal growth factor receptor (EGFR), which is activated by binding of its ligand, epidermal growth factor (EGF) ...
7
Epidermal growth factor receptor inhibition reduces angiogenesis via hypoxia-inducible factor-1α and Notch1 in head neck squamous cell carcinoma.
... that epidermal growth factor re- ceptor (EGFR)-mediated aberrant signaling transduction is crucial in HNSCC tumorigenesis and progression ...Hypoxia-inducible factor-1α (HIF-1α) is a principal ...
17
Epidermal growth factor receptors, testosterone levels and parotid gland changes in rats infected with Trypanosoma cruzi
... It has been demonstrated that parotid glands of rats infected with Trypanosoma cruzi present severe histologi- cal alterations; changes include reduction in density and volume of the acini and duct systems and an ...
5
Epidermal growth factor signalling controls myosin II planar polarity to orchestrate convergent extension movements during Drosophila tubulogenesis.
... localised epidermal growth factor (EGF) signalling from the distally placed tip cell lineage, which sets up a distal-to-proximal gradient of pathway activation to planar polarise cells, without the ...
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Autonomous growth of BALBMK keratinocytes transfected with a retroviral vector carrying the human epidermal growth factor gene
... Epidermal growth factor (EGF), which promotes epidermal regeneration and wound closure, is important for the pro- liferation and differentiation of epidermal and epithelial tissues in ...
5
A temporal signature of epidermal growth factor signaling regulates the differentiation of germline cells in testes of Drosophila melanogaster.
... Tissue replenishment from stem cells follows a precise cascade of events, during which stem cell daughters first proliferate by mitotic transit amplifying divisions and then enter terminal differentiation. Here we ...
12
Polycythaemia-inducing mutations in the erythropoietin receptor (EPOR): mechanism and function as elucidated by epidermal growth factor receptor-EPOR chimeras
... the epidermal growth factor receptor (EGFR), a tyrosine kinase also known as HER1 or ErbB-1 (Yarden, 2001; Krampera et al, 2005; Normanno et al, ...
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Comparing the epidermal growth factor interaction with four different cell lines: intriguing effects imply strong dependency of cellular context.
... the epidermal growth factor (EGF) interacting with the EGF receptor ...The epidermal growth factor receptor family consists of four members: EGFR (HER1/ErbB1), HER2, HER3 and ...
7
Bio-imaging of colorectal cancer models using near infrared labeled epidermal growth factor.
... the epidermal growth factor receptor (EGFR) have led to the clinical development of monoclonal antibodies, which treat metastatic colorectal cancer (mCRC) but only subgroups of patients with ...
13
Transgenic Soybean Production of Bioactive Human Epidermal Growth Factor (EGF).
... Epidermal growth factor protein from humans was produced in soybean seeds by constructing a plant gene expression cassette that involved a synthetic codon optimized EGF nucleotide sequence (protein ...
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Differential regulation of type I interferon and epidermal growth factor pathways by a human Respirovirus virulence factor.
... bridges Epidermal Growth Factor (EGF) receptor to MAPK/ERK pathway, a signaling cascade recently found to be involved in airway inflammatory ...initiation factor 4E ...virulence factor ...
15
Molecular determinants of epidermal growth factor binding: a molecular dynamics study.
... The epidermal growth factor receptor (EGFR) is a member of the receptor tyrosine kinase family that plays a role in multiple cellular ...determining factor in activation of a downstream ...
12
The expression of the epidermal growth factor (EGF) during odontogenesis:
... the epidermal growth factor (EGF) in the odontogenesis of the first upper molar in Mus musculus mice, relating it to the microscopic morphologic ...
7
Coarse-grained molecular simulation of epidermal growth factor receptor protein tyrosine kinase multi-site self-phosphorylation.
... the epidermal growth factor receptor (EGFR), the intrinsic protein tyrosine kinase (PTK) activity of one receptor monomer is activated, and the dimeric receptor undergoes self-phosphorylation at any ...
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Baseline and Trend of Lymphocyte-to-Monocyte Ratio as Prognostic Factors in Epidermal Growth Factor Receptor Mutant Non-Small Cell Lung Cancer Patients Treated with First-Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors.
... Patients with early-stage lung cancer who have a high baseline lymphocyte-to-monocyte ratio (LMR) have a favorable prognosis. However, the prognostic significance of LMR in patients with advanced-stage EGFR-mutant ...
13
AST1306, a novel irreversible inhibitor of the epidermal growth factor receptor 1 and 2, exhibits antitumor activity both in vitro and in vivo.
... wild-type epidermal growth factor receptor (EGFR) and ErbB2 as well as EGFR resistant mutant in both cell-free and cell-based ...tumor growth in ErbB2-overexpressing adenocarcinoma xenograft ...
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