Factor receptor
Expression of epidermal growth factor receptor (EGFR) in cholangiocarcinomas: predictive factors and survival
... growth factor receptor (EGFR) is a cell membrane receptor tyrosine kinase encoded by ...growth factor (EGF), heparin binding factor (HB-EGF), and amphiregulin, couple in the ...
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Polycythaemia-inducing mutations in the erythropoietin receptor (EPOR): mechanism and function as elucidated by epidermal growth factor receptor-EPOR chimeras
... Primary familial and congenital polycythaemia (PFCP) is a disease character- ized by increased red blood cell mass, and can be associated with mutations in the intracellular region of the erythropoietin (EPO) ...
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Tumor necrosis factor receptor associated factor 6 is not required for atherogenesis in mice and does not associate with atherosclerosis in humans.
... Necrosis Factor Receptor associated factors in Cardiovascular Risk Study (TRAFICS) approved by the local Institutional Review Board (ethic committees: Ethikkommission der Albert- Ludwigs- Universita¨t ...
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Gefitinib and Erlotinib Lead to Phosphorylation of Eukaryotic Initiation Factor 2 Alpha Independent of Epidermal Growth Factor Receptor in A549 Cells.
... growth factor receptor (EGFR) tyrosine ...initiation factor (eIF) 2α/activating transcription factor 4 pathway without protein kinase R-like ER kinase activation in A549 ...
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Baseline and Trend of Lymphocyte-to-Monocyte Ratio as Prognostic Factors in Epidermal Growth Factor Receptor Mutant Non-Small Cell Lung Cancer Patients Treated with First-Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors.
... Patients with early-stage lung cancer who have a high baseline lymphocyte-to-monocyte ratio (LMR) have a favorable prognosis. However, the prognostic significance of LMR in patients with advanced-stage EGFR-mutant ...
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Epidermal growth factor receptor inhibition reduces angiogenesis via hypoxia-inducible factor-1α and Notch1 in head neck squamous cell carcinoma.
... the receptor tyrosine kinase-mediated angio- genesis in head neck squamous cell carcinoma ...The receptor tyrosine kinase activity in a transgenic mouse model of HNSCC was ...growth factor ...
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Adverse cutaneous reactions to epidermal growth factor receptor inhibitors: a study of 14 patients
... average 13.5 days after starting the drug treatment. The patients underwent oral treatment with minocycline or doxycycline and topical treatment with metronidazole, benzoyl peroxide and/or corticosteroids. All patients ...
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Coarse-grained molecular simulation of epidermal growth factor receptor protein tyrosine kinase multi-site self-phosphorylation.
... growth factor receptor (EGFR), the intrinsic protein tyrosine kinase (PTK) activity of one receptor monomer is activated, and the dimeric receptor undergoes self-phosphorylation at any of ...
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Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A).
... Growth Factor Receptor 3 (FGFR3) as a high affinity receptor for ...novel receptor for BoNT/A represents an important advance in the understanding of the mechanism of action of BoNT/A, ...
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Fibroblast growth factor 10-fibroblast growth factor receptor 2b mediated signaling is not required for adult glandular stomach homeostasis.
... growth factor 10 (FGF10) and its main receptor, Fibroblast growth factor receptor 2b (FGFR2b), in adult glandular stomach ...main receptor, which acts as a dominant negative, we found ...
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A Functional Role of Fibroblast Growth Factor Receptor 1 (FGFR1) in the Suppression of Influenza A Virus Replication.
... growth factor receptor (FGFR) 1 to 4, known as the tyrosine kinase receptor super- family, regulates many biological processes including differentiation, proliferation, develop- ment, and ...
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Epidermal growth factor receptor (EGFR) mutations in lung cancer: preclinical and clinical data
... Lung cancer leads cancer-related mortality worldwide. Non-small-cell lung cancer (NSCLC), the most prevalent subtype of this recalcitrant cancer, is usually diagnosed at advanced stages, and available systemic therapies ...
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Internalization mechanisms of the epidermal growth factor receptor after activation with different ligands.
... growth factor receptor (EGFR) regulates normal growth and differentiation, but dysregulation of the receptor or one of the EGFR ligands is involved in the pathogenesis of many ...the receptor ...
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Fibroblast growth factor receptor 1 amplification in non-small cell lung cancer by quantitative real-time PCR.
... Introduction: Amplification of the fibroblast growth factor receptor 1 (FGFR1) gene has been described in tumors of non-small-cell lung cancer (NSCLC) patients.. Prior reports showed co[r] ...
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Comprehensive analysis of fibroblast growth factor receptor expression patterns during chick forelimb development
... to receptor dimerisation and activation of downstream intracellular signalling cascades, such as Ras-MAP kinase, PI3 kinase/Akt and PLC gamma/PKC (re- viewed in Dailey et ...
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Nitric oxide from inflammatory origin impairs neural stem cell proliferation by inhibiting epidermal growth factor receptor signaling
... Following the various experimental treatments, as detailed in figure legends, the cultures were lysed in 20 mM Tris-HCl, 100 mM NaCl, 2 mM EDTA, 2 mM EGTA, supplemented with 100 μM PMSF, 1 mM dithiothreitol, 1 μg/ml ...
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Search for a platelet-activating factor receptor in the Trypanosoma cruzi proteome: a potential target for Chagas disease chemotherapy
... Tc00.1047053510861.94 -FKLVVNCLMLLFLILIAVMFH-- --HPRFFFSVALLLLAVFDIVLR- ---HYIAIVADTLAVAYVFTTSVR LESIFLGLTGLLLSVNLLSYI---- -LGFAMSVAPIFFGFALFFCIV-- MGFSLVALYFVMFGDAILPAI--- LIVTVLANFMTIL[r] ...
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Gefitinib induces epidermal growth factor receptor dimers which alters the interaction characteristics with ¹²⁵I-EGF.
... Interaction Maps, depicts a reality where EGF interacts with not only one receptor form, but several. The different receptor populations may be the monomeric, heterodimeric and homodimeric form of EGFR. The ...
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Role of the neurotrophic factor receptor RET in haematopoiesis
... kinase receptor RET has a myriad of functions that include the provision of migratory and survival signals to several neuronal subpopulations, regulation of spermatogenesis, renal development and enteric lymphoid ...
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Expression, mutation and copy number analysis of platelet derived growth factor receptor A
... growth factor (PDGF) has also been implicated in cancer, including central nervous system tumours (Shih and Holland, ...PDGF receptor stimulation may contribute to their growth (Hermanson et al, 1992; ...
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