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gene amplification

Gene amplification in carcinogenesis

Gene amplification in carcinogenesis

... of gene amplification and protein expression are very similar to those found in patients with breast cancer (Ross and McKenna, 2001; Ross and Gray, ...with amplification of the c-MYC and c-MET ...

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A mechanism of gene amplification driven by small DNA fragments.

A mechanism of gene amplification driven by small DNA fragments.

... DNA amplification resulting in tandem duplications in mammalian ...of gene amplification observed in Chinese hamster cells [34,50], as well as in various human cancers ...

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Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis.

Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis.

... occurring during esophageal neoplastic progression [7-10]. In several instances, it has also been possible to identify the proximate genomic or epigenetic mechanism (for example, intragenic deletion, truncating mutation, ...

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HER2 status in colorectal cancer: its clinical significance and the relationship between HER2 gene amplification and expression.

HER2 status in colorectal cancer: its clinical significance and the relationship between HER2 gene amplification and expression.

... HER2 gene amplification, and similar to the rates seen in gastro-esophageal cancer in the previous studies ...HER2 gene amplification with homogenous distribution, but HER2 protein was not ...

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Central giant cell lesion of the jaws : study of CCND1 gene amplification and p16INK4a protein levels

Central giant cell lesion of the jaws : study of CCND1 gene amplification and p16INK4a protein levels

... Abstract Central giant cell lesions (CGCLs) are uncommon benign jaw lesions with uncertain etiology and a variable clinical behavior. In neoplasms, alterations in molecules involved in the G1/S checkpoint are frequently ...

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Analysis of EGFR overexpression, EGFR gene amplification and the EGFRvIII mutation in Portuguese high-grade gliomas

Analysis of EGFR overexpression, EGFR gene amplification and the EGFRvIII mutation in Portuguese high-grade gliomas

... overexpression, gene amplification and gene ...EGFR amplification were determined by immunohistochemistry and chromogenic in situ hybridization (CISH) in 27 primary glioblastomas (GBM), 24 ...

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Dissection of the beta-globin replication-initiation region reveals specific requirements for replicator elements during gene amplification.

Dissection of the beta-globin replication-initiation region reveals specific requirements for replicator elements during gene amplification.

... Gene amplification plays a pivotal role in malignant transformation of human ...involves amplification at the extrachromosomal site, followed by amplification at the chromosomal arm, ...

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Clonal multidrug-resistant Corynebacterium striatum within a nosocomial environment, Rio de Janeiro, Brazil

Clonal multidrug-resistant Corynebacterium striatum within a nosocomial environment, Rio de Janeiro, Brazil

... Gene amplification and sequencing - ...rRNA gene was amplified using universal primers pA (5’-AGAGTTTGATCCTGGCTCAG) and pH (5’-AAG- GAGGTGATCCAGCCGCA), as described by Watts et ...rpoB gene ...

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Fibroblast growth factor receptor 1 amplification in non-small cell lung cancer by quantitative real-time PCR.

Fibroblast growth factor receptor 1 amplification in non-small cell lung cancer by quantitative real-time PCR.

... FGFR1 gene amplification by real-time quantitative PCR, which is technically less complex, automated, quantitative, and independent of reader ...3.5-fold amplification of the FGFR1 gene was ...

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Clinicopathological Features and Prognosis of Metaplastic Breast Carcinoma: Experience of a Major Chinese Cancer Center.

Clinicopathological Features and Prognosis of Metaplastic Breast Carcinoma: Experience of a Major Chinese Cancer Center.

... overexpression/gene amplification are independent predictive factors for decreased ...and/or gene amplification of EGFR is worthy of fur- ther ...

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Rev. Bras. Hematol. Hemoter.  vol.32 número5

Rev. Bras. Hematol. Hemoter. vol.32 número5

... Venipuncture is one of the easiest clinical procedures to obtain viable blood samples to evaluate gene expression using mRNA analysis. However, the use of this sample type in reverse transcriptase polymerase chain ...

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Analysis of viral protein-2 encoding gene of avian encephalomyelitis virus from field specimens in Central Java region, Indonesia

Analysis of viral protein-2 encoding gene of avian encephalomyelitis virus from field specimens in Central Java region, Indonesia

... no amplification product of VP-2 gene. Amplification products of the VP-2 encoding gene of AEV by RT-PCR methods of various type of poultry from field specimens showed a positive results on ...

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Rev. Soc. Bras. Med. Trop.  vol.31 número5

Rev. Soc. Bras. Med. Trop. vol.31 número5

... 11. Jin O, Sole MJ, Butary JW, Chia WK, Mc Laughlin PR, Liu P, Liew CC. Detection of enterovirus RNA in myocardial biopsies from patients with myocarditis and cardiomyopathy using gene amplification by ...

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Avaliação do HER2 em câncer de mama: estudo das fases pré-analítica, analítica e pós-analítica das técnicas de imuno-histoquímica e hibridização in situ pela prata usando microarranjos de tecido

Avaliação do HER2 em câncer de mama: estudo das fases pré-analítica, analítica e pós-analítica das técnicas de imuno-histoquímica e hibridização in situ pela prata usando microarranjos de tecido

... AIMS: To investigate the influence of preanalytical phase control (PAPC) for assessment of immunohistochemistry (IHC) HER2 expression against in situ hybridization (DDISH); to compare automated and manual IHC ...

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Sambo, Patrícia Muíla Bragança

Sambo, Patrícia Muíla Bragança

... Recently, the role of riboflavin has been also explored. Some studies suggest that high intake of riboflavin may enhance folate protective effect in colorectal adenomas, which seems to be more significant in TT genotype ...

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Variability in Ribosomal DNA Genic and Spacer Regions in Verticillium dahliae Isolates from Different Hosts

Variability in Ribosomal DNA Genic and Spacer Regions in Verticillium dahliae Isolates from Different Hosts

... Amplification of the nuclear rDNA IGS spacer region yielded a single PCR product of approximately 2200 bp for all isolates. Phenetic analyses were conducted individually for each restriction enzyme used (data not ...

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Alternating antibiotics render resistant bacteria beatable.

Alternating antibiotics render resistant bacteria beatable.

... a gene that en- codes a multidrug efflux pump, the genomic amplification of which results in increased drug resistance to both ...and amplification of the efflux pump, the authors identified ...

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Comparison of LAMP and PCR for molecular mass screening of sand flies for Leishmania martiniquensis infection

Comparison of LAMP and PCR for molecular mass screening of sand flies for Leishmania martiniquensis infection

... The PCR-mkDNA using primers L.MC-1S/ L.MC-1R can detect at least one L. (L.) major existed in a sand fly sample (Kato et al. 2007). Along the similar line, this as- say also showed the highest analytical sensitivity to ...

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Edina Rodrigues Pires, Teofânia HDA Vidigal, Horácio MS Teles, Andrew JG Simpson, Omar S Carvalho

Edina Rodrigues Pires, Teofânia HDA Vidigal, Horácio MS Teles, Andrew JG Simpson, Omar S Carvalho

... Although Biomphalaria occidentalis and B. tenagophila are indistinguishable on the basis of shell morphology and the majority of their genital organs, only the latter is susceptible to infection with Schistosoma mansoni. ...

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PCR AMPLIFICATION AND SEQUENCING

PCR AMPLIFICATION AND SEQUENCING

... Taxonomic identification of the species involved in the processes of cadaveric decomposition is a fundamental procedure in forensic entomological analysis. Among the species involved in the processes of decay, those of ...

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