HIF-1?.
Clonagem e expressão do fator 1 humano induzível por hipóxia (HIF-1) na levedura Saccharomyces cerevisiae
... do HIF na expressão gênica pode ser diferente de acordo com os tipos ...exemplo, HIF-1α e -2α são abundantemente expressos no rim, enquanto foi verificada uma alta expressão de HIF-3α em células ...
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Produção de VEGF e HIF-1? em pacientes com carcinoma de mama localmente avançado...
... do HIF-1 (Petit et ...de HIF-1 no câncer de mama humano estão relacionadas à carcinogênese mamária e modificações moleculares decorrentes deste ...de HIF-1 (Zhong et ...de ...
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Hypoxia inducible factor 1-alpha (HIF-1 alpha) is induced during reperfusion after renal ischemia and is critical for proximal tubule cell survival.
... biopsies, HIF-1 a was exclusively detected in proximal tubule cells which did not exhibit marked ischemic damage or show regeneration ...of HIF-1 a was observed in the biopsies which clearly ...
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Oxygen-independent stabilization of hypoxia inducible factor (HIF)-1 during RSV infection.
... of HIF-1a as transcriptional regulator of inflam- mation and ...example, HIF-1a is essential for myeloid cell-mediated inflammation, bactericidal capacity of phagocytes [17] and mice with conditional ...
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Estudo das expressões imunoistoquímicas dos marcadores HIF-1, VEGF e PDGF-C correlacionados...
... 1 INTRODUÇÃO.................................................................................. 1.1 Neoplasias do Sistema Nervoso Central........................................ 1.1.1 Incidência e fatores de risco ...
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Propranolol inhibits the proliferation, migration and tube formation of hemangioma cells through HIF-1 a dependent mechanisms
... increased HIF-1a levels were found in hemangioma tissues compared to normal vascular tissues, and its levels were decreased by propranolol ...of HIF-1a protein in a dose- and time-dependent ...
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Mechanism of hif-1 a mediated hypoxia-induced permeability changes in bladder endothelial cells
... transfected HIF-1a RNAi expression vector ...inhibit HIF-1a gene expression (Po0.05). HIF-1a and VEGF expression in the hypoxic group and siHIF-1a hypoxic group were significantly higher than normal ...
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Análise da marcação imunohistoquímica do fator induzido por hipóxia1α em carcinoma epidermóide oral e em lesões malignas
... of HIF-1 in oral squamous cell carcinoma and premalignant lesions presenting oral epithelial ...with HIF-1 antibody (Abcam mark, 1:200 dilution, 60 min pH6 citrate antigen retrieval ...
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NADPH oxidase 4 mediates insulin-stimulated HIF-1α and VEGF expression, and angiogenesis in vitro.
... Transient transfection and luciferase assay were performed as described previously [23]. A 2.65 kb human VEGF gene promoter in pGL2-basic luciferase reporter and a 46 bp human VEGF gene promoter containing the ...
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Braz. Dent. J. vol.27 número2
... tested HIF-1α activation of in periodontal ligament cells of Porphyromonas gingivalis, and observed a significant increase in HIF-1 α mRNA after 4 hours incubation under hypoxic conditions and a more ...
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The role of the HIF-1α transcription factor in increased cell division at physiological oxygen tensions.
... of HIF-1a at physiological oxygen tensions is likely to be very ...of HIF- 1a, the elevated cell growth rates usually observed at physiological oxygen tensions [3,4] were severely ...of HIF-1 ...
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Int. braz j urol. vol.43 número3
... The HIF heterodimer can translocate to the nucleus and transactivate the target genes, many of which pro- mote adaptation to acute or chronic hypoxia, in- cluding vascular endothelial growth factor (VEGF), which ...
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Nicotine promotes proliferation of human nasopharyngeal carcinoma cells by regulating α7AChR, ERK, HIF-1α and VEGF/PEDF signaling.
... (B), HIF-1a-specific siRNA (si-HIF-1, 100 nM) or non-specific siRNA control (si-NS, 100 nM) (D, E) for 4 hours followed by nicotine (10 mM) treatment for 24 ...of HIF-1a proteins in NPC cells ...
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Análise imuno-histoquímica das proteínas VEGF e HIF-1α na doença periodontal
... o HIF-1 α (Fator induzido por hipóxia -1 ...para HIF-1 α, nos espécimes de periodontite e gengivites crônicas, em relação aos sítios saudáveis, porém, sem diferenças estatísticas entre ...
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Rev. Bras. Reumatol. vol.57 número2
... do HIF-1␣ pode comec¸ar pela ligac¸ão de diferen- tes proteínas a seus receptores na membrana celular; essas proteínas podem ser enzimas, fatores de crescimento, inter- leucinas ou outros tipos de ...
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Differential HIF-1α and HIF-2α Expression in Mammary Epithelial Cells during Fat Pad Invasion, Lactation, and Involution.
... factors HIF-1 and HIF-2 has been associated with meta- static, poor prognosis, and high-grade breast ...oxygen-sensitive HIF-alpha subunits during mouse mammary gland development, lactation, ...
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PI3K and ERK-induced Rac1 activation mediates hypoxia-induced HIF-1α expression in MCF-7 breast cancer cells.
... increases HIF-1a transcriptional activity by increasing HIF-1/p300 complex formation ...activated HIF-1a mRNA transcription level under hypoxia in MCF-7 human breast cancer ...controlling ...
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Imunoexpressão do fator induzido por hipóxia em carcinoma basocelular
... Hipóxia, HIF-1. OBJETIVOS: Avaliar a expressão imuno-histoquímica do HIF-1α em CBC; correlacionar a imunoexpressão do HIF-1α com tecido normal, subtipos histológicos e parâmetros clínicos de ...
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Rev. Bras. Reumatol. vol.57 número2
... with HIF-1␣, but not have been evaluated in OA and that may be of clinical importance in this ...factor-inhibiting HIF-1␣ (FIH-1), which regulate cellular HIF- 1␣ ...
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