Microglia cells
Control of microglia morphodynamics by the small RhoGTPase RhoA
... human microglia cell line ...primary microglia cells present several advantages that ultimately led to our ...primary microglia (by processes of gene knockout, using CRISPR-Cas9, for example) ...
51
Targeting microglia necroptosis to arrest neuroinflammation
... host cells, and aid in returning the damaged area to its normal ...called microglia cells in the CNS, in addition to an increased expression of acute phase proteins and proinflammatory cytokines ...
117
Histamine modulates nitric oxide release by microglia and dopaminergic neuronal survival
... infection, microglia cells, the immune resident cells in the brain, became activated and release a cocktail of inflammatory molecules, migrate to the injury site and became ...by microglia ...
55
The role of microglia in methamphetamine exposure
... and microglia activation (Ridet, Privat et ...activated microglia (Suzumura, Sawada et ...microglial cells exposed to ...that microglia cells do not acquire an anti-inflammatory ...
72
Microglia Susceptibility to Free Bilirubin Is Age-Dependent
... glial cells. We demonstrated that UCB damages neurons and glial cells by compromising oligodendrocyte maturation and myelination, and by activating astrocytes and ...whether microglia susceptibility ...
16
Anti-inflammatory effects of vinpocetine in LPS-stimulated microglia via activation of AMPK
... Microglia cells contribute to CNS development and help to maintain tissue homeostasis by supporting neuronal survival, cell death and ...of microglia leads to neuronal death, brain injury, and the ...
10
VEGF receptor blockade markedly reduces retinal microglia/macrophage infiltration into laser-induced CNV.
... accumulated cells are other types of ...Iba1(+) cells were generally negative or very weak for VEGFR1 or ...CD45(+) cells were always positive for VEGFR1 or ...of cells, which may rely on some ...
15
The role of the surface on microglia function: Implications for central nervous system tissue engineering
... of microglia cells when seeded on different P(TMC-CL) surfaces was analysed after immunolabelling of ...films, microglia present a round shape and long protrusions (figure ...Conversely, ...
20
The spider effect: morphological and orienting classification of microglia in response to stimuli in vivo.
... microglial cells move from their resting location in the vicinity of the site of injury to the cutting edge of the injury in their activated stage and then back to the original location in their then again resting ...
12
Neuronal synapse formation induced by microglia and interleukin 10.
... containing cells were transferred to new conical ...containing cells was centrifuged at 1400 rpm 5 min and the resulted pellet was added with the glial media (DMEM media with 10% FBS, 1 mM L-glutamine, 1 mM ...
13
Relação entre o padrão de citocinas secretadas por células de microglia ativadas...
... INTRODUCTION: Microglia cells has gained great attention recently because its activation by inflammatory cytokines can promote infiltration and destruction of Central Nervous System (CNS) during some ...
90
Somatostatin modulates insulin-degrading-enzyme metabolism: implications for the regulation of microglia activity in AD.
... by microglia involved in Ab degradation, even though the molecular basis of IDE regulation are poorly known ...[5]. Microglia seems to cover a two-fold role in AD ...early microglia activation exerts ...
8
Efeito in vitro da infecção por taquizoítos de n. caninum sobre microglia de córtex cerebral de ratos neonatos
... de microglia de ratos, após estímulo com LPS e IFN-γ sofreram morte celular via apoptose através da liberação de ...com microglia de murinos e mesma fonte de estímulo (LPS e IFN-γ), demonstraram que a ...
62
Microglia Activate Migration of Glioma Cells through a Pyk2 Intracellular Pathway.
... glioma cells. Microglia infiltrate most glioma tumors and, therefore, make up an important component of the glioma ...that microglia can promote glioma migration through a mechanism independent of ...
18
ALS pathogenesis: role of motor neuron-derived exosomes in microglia activation and dysfunction
... of microglia phagocytic ability, acute release of NO, MMP-2 and MMP-9, and interleukin (IL)-1β and tumor necrosis factor (TNF)-α expression, together with lasting NF-κB activation and delayed increase of ...
112
Exploring deregulated signals involved in Motor neuron-Microglia cross-talk in ALS
... microglial cells that is decreased and not the number of mMNs, we may assume that microglial phagocytic activity is compromised in our model of mixed cultures with ...impairing microglia phagocytic ability ...
88
Interleukin-6 expression by hypothalamic microglia in multiple inflammatory contexts: a systematic review
... distant cells that express gp130 but not surface-bound IL-6R [20, ...glial cells [24]. Microglial cells are the resident macrophages of the central nervous system (CNS) and are widely distributed ...
13
Estudo da expressão de PPARs em células de microglia (BV-2) infectadas pelas linhagens asiática e africana do vírus Zika
... O diferencial aumento da expressão do receptor nucelar PPARγ em células BV2 induzido pela infecção com os isolados PE243 e MR766 do ZIKV, pode ter um papel relevante na [r] ...
99
Efeitos dos glicocorticoides nas interações celulares de astrócitos, microglia e neurônios durante inflamação induzida por LPS em modelo in vitro.
... astrócitos, microglia e neurônios na presença de um estímulo inflamatório agudo, o LPS, em modelos in vitro de culturas primárias derivadas do córtex cerebral de ratos ...A microglia participa da resposta ...
31
Reprogramming primordial germ cells into pluripotent stem cells.
... In our previous study we found that the presence of FGF-2 is critical during the first day but it is dispensable thereafter, when presumably the PGCs begin to switch from their in vivo develop- mental programme towards ...
8