mitochondrial dysfunction
Mitochondrial Dysfunction in Duchenne Muscular Dystrophy
... between mitochondrial dysfunction and DMD where increased intra- cellular and inter-mitochondrial calcium has been shown to cause mitochondrial swelling, loss of mitochondrial membrane ...
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Differential regional and subtype-specific vulnerability of enteric neurons to mitochondrial dysfunction.
... Mitochondrial dysfunction is a central mediator of disease progression in diverse neurodegenerative diseases that often present with prominent gastrointestinal ...Gastrointestinal dysfunction in ...
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Mitochondrial Dysfunction and Insulin Resistance: The Contribution of Dioxin-Like Substances
... the mitochondrial genome, at least in ...that mitochondrial dysfunction does not cause the metabolic syndrome in ...with mitochondrial DNA mutations manifest ...as mitochondrial ...
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A Regulated Response to Mitochondrial Dysfunction Modulates Longevity and Rates of Living
... and mitochondrial dysfunction can cause disease and accelerate ...Paradoxically, mitochondrial dysfunction can also increase ...lack mitochondrial DNA and do not carry out respiration, ...
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A novel proteasome inhibitor acting in mitochondrial dysfunction, ER stress and ROS production
... in mitochondrial dysfunction and damage, as well as ROS production [13, ...outer mitochondrial membrane, the nuclear envelope and the endoplasmic reticulum (ER) of ...the mitochondrial mem- ...
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Mitochondrial Dysfunction Plus High-Sugar Diet Provokes a Metabolic Crisis That Inhibits Growth.
... of mitochondrial dysfunction in relation to diet is therefore largely ...of mitochondrial protein synthesis impairs ...of mitochondrial and cytosolic translational ...
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Linking Glycation and Glycosylation With Inflammation and Mitochondrial Dysfunction in Parkinson’s Disease
... mitochondria dysfunction plays a central role in the neurodegenerative process in ...glycosylated mitochondrial proteins (Levrat et ...that mitochondrial glycome may dictate mitochondrial ...
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Mitochondrial dysfunction and apoptosis in cumulus cells of type I diabetic mice.
... that mitochondrial dysfunction and the resultant apoptosis in cumulus cells may compromise the competence of oocyte in diabetic mice through the following possible ...and mitochondrial ...
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Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence.
... of mitochondrial function revealed significant mitochondrial dysfunction in senescent fibroblast cultures as well as a global change in gene expression pattern indicative of enhanced retrograde signal- ...
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Soluble products of Escherichia coli induce mitochondrial dysfunction-related sperm membrane lipid peroxidation which is prevented by lactobacilli.
... coli-induced mitochondrial dysfunction, their protective effect against membrane lipid peroxidation could reflect the intervention of anti-oxidant factors at the membrane ...
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Mitochondrial dysfunction increases oxidative stress and decreases chronological life span in fission yeast.
... that mitochondrial dysfunction could trigger ROS formation at other cellular ...other mitochondrial mutants (Figure 2A), which could be explained if ubiquinone deficiency both enhances ROS production ...
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Mitochondrial dysfunction is involved in the toxic activity of boric acid against Saprolegnia.
... detected. Mitochondrial degeneration was the most obvious sign observed following 4 h treatment in about 20% of randomly selected ...division, mitochondrial activity and function using confocal laser ...
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Investigation of mitochondrial dysfunction by sequential microplate-based respiration measurements from intact and permeabilized neurons.
... implicates mitochondrial dysfunction and associated oxidative stress in aging and neurodegenerative diseases such as Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, amyotrophic lateral ...
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Lithocholic acid induces endoplasmic reticulum stress, autophagy and mitochondrial dysfunction in human prostate cancer cells
... induces mitochondrial dysfunction in PC-3 and DU-145 cells We have shown that LCA impairs mitochondrial function by increasing mitochondrial outer-membrane permeability ...impairs ...
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Liver mitochondrial dysfunction and oxidative stress in the pathogenesis of experimental nonalcoholic fatty liver disease
... Therefore, mitochondrial dysfunction may play a central role in the accumulation of fat in the liver (“first hit”) and the exces- sive production of ROS by mitochondria may result in lipid peroxidation ...
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The morphological changes of cardiomyocytes and mitochondrial dysfunction in spontaneous hypertensive rats with experimental diabetes mellitus
... and mitochondrial dysfunction in spontaneous hypertensive rats with experi- mental diabetes ...The mitochondrial state was assessed by investigation of the permeability of the giant ...
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Benzaldehyde thiosemicarbazone derived from limonene complexed with copper induced mitochondrial dysfunction in Leishmania amazonensis.
... The TEM ultrastructural analysis demonstrated that BenzCo induced alterations in the mitochondria of treated promastigotes, and we decided to evaluate the mitochondrial membrane potential by flow cytometry using ...
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Acetyl-L-Carnitine Neuroprotection in Mitochondrial Dysfunction
... Fariello et al. found that ALC administration to mice for 5 consecutive days raised nigral GABA, but striatal levels of dopamine and metabolites were not significantly affected. The authors suggested that ALC would be ...
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New signalling pathways in reproductive tissues associated with mitochondrial dysfunction induced by metabolic diseases
... erectile dysfunction and ejaculation difficulties (Al-Roujeaie et ...reproductive dysfunction that resulted from a decrease in the reproductive organ weights and in sperm counts (Scarano et ...
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Maternal obesity during gestation impairs fatty acid oxidation and mitochondrial SIRT3 expression in rat offspring at weaning.
... obesity, mitochondrial changes may be an important conduit on how maternal obesity mediates program- ming of offspring ...metabolism. Mitochondrial dysfunction is highly associated with reduced FAO ...
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