Promyelocytic Leukemia
Arterial thrombosis in acute promyelocytic leukemia.
... promyeloclocytic leukemia can present coagulopathies which are frequently very serious due to hemorrhagic ...acute promyelocytic leukemia with transposition (15;17) Treatment with ATRA and Idarubicin ...
2
Addition of Arsenic Trioxide into Induction Regimens Could Not Accelerate Recovery of Abnormality of Coagulation and Fibrinolysis in Patients with Acute Promyelocytic Leukemia.
... myeloid leukemia, patients with acute promyelocytic leukemia had lower platelet counts and fibrinogen levels, significantly prolonged prothrombin time and elevated D-dimers ...Acute ...
11
Acute promyelocytic leukemia: the study of t(15;17) translocation by fluorescent in situ hybridization, reverse transcriptase-polymerase chain reaction and cytogenetic techniques
... Acute promyelocytic leukemia (AML M3) is characterized by the t(15;17)(q22;q11- 21) translocation described by Rowley et ...the promyelocytic stage of myeloid maturation ...
9
All-Trans Retinoic Acid plus Arsenic Trioxide versus All-Trans Retinoic Acid plus Chemotherapy for Newly Diagnosed Acute Promyelocytic Leukemia: A Meta-Analysis.
... 20. Shen ZX, Shi ZZ, Fang J, Gu BW, Li JM, Zhu YM, et al. All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia. Proceedings ...
10
Clinical features and outcomes of 134 Brazilians with acute promyelocytic leukemia who received ATRA and anthracyclines
... 10. Ruiz-Arguelles GJ, Garces-Eisele J, Reyes-Nunez V, Gomez-Rangel JD, Ruiz-Delgado GJ. More on geographic hematology: the breakpoint cluster regions of the PML/RARα fusion gene in Mexican Mestizo patients with ...
2
Effect of all-trans retinoic acid on newly diagnosed acute promyelocytic leukemia patients: results of a Brazilian center
... acute promyelocytic leukemia: a pilot study on 26 ...acute promyelocytic leu- kemia: Impact of leukocytosis, low -dose chemotherapy, PM N/RAR-α isoform, and CD13 expression in patients treated w ith ...
8
Recent advances in the diagnosis and management of childhood acute promyelocytic leukemia
... acute promyelocytic leukemia (APL) has markedly ...the promyelocytic leu- kemia/retinoic acid receptor-alpha (PML/RARα) isoforms bcr 2 and bcr 3 is higher in children than in ...
11
Cellular promyelocytic leukemia protein is an important dengue virus restriction factor.
... The intrinsic antiviral resistance response, unlike cytokine-mediated response, involves the ac- tions of pre-existing cellular proteins to repress viral replication [1, 2]. This group of proteins with potent antiviral ...
17
Guidelines on the diagnosis and treatment for acute promyelocytic leukemia: Associacao Brasileira de Hematologia, Hemoterapia e Terapia Celular Guidelines Project: Associacao Medica Brasileira - 2013
... Mortality rate of 16.34% was observed during the induction treatment with deaths due to infection, pulmonary or cerebral hemorrhage and Differentiation syndrome; 3.8% of the deaths during consolidation treatment were by ...
22
Rev. Bras. Hematol. Hemoter. vol.38 número4
... Acute promyelocytic leukemia has good prognosis in view of the high complete remission and survival rates achieved with therapies containing all-trans retinoic acid or arsenic tri- ...Acute ...
6
Possible benefit of consolidation therapy with high-dose cytarabine on overall survival of adults with non-promyelocytic acute myeloid leukemia
... non- promyelocytic leukemia who were treated in a single center to identify variables that could have affected the outcomes, including the role of three distinct doses of cytarabine administered in the ...
8
J. Bras. Patol. Med. Lab. vol.44 número1
... Hybrid gene PML-RARα is the molecular target found in most cases of acute promyelocytic leukemia (APL) and has been used for diagnosis and minimal residual disease studies. The standard molecular technique ...
4
J. Braz. Chem. Soc. vol.26 número4
... acute promyelocytic leukemia cells (NB4), human lung adenocarcinoma (A549), human neuroblastoma (SHSY5Y), human prostate (PC3), and human breast adenocarcinoma (MCF7) tumor cell lines were purchased from ...
5
Rev. Bras. Hematol. Hemoter. vol.26 número3
... that leukemia cells have to bind to FN and/or Coll IV associated or not with ...acute promyelocytic leukemia cells (HL-60), histiocytic lymphoma derived cells (U937), chronic myelocytic ...
6
Do paradigma molecular ao impacto no prognóstico: uma visão da leucemia promielocítica aguda.
... Acute promyelocytic leukemia (APL) is a model of clinical applicability of the knowledge of molecular ...myeloid leukemia due to a higher incidence in young adults and in countries of “Latin” ...
8
Rev. Bras. Hematol. Hemoter. vol.33 número6
... acute promyelocytic leukemia with all-trans retinoic acid and anthracycline monochemotherapy: long-term outcome of the LPA 99 multicenter study by the PETHEMA ...
3
Rev. Bras. Hematol. Hemoter. vol.39 número1
... acute promyelocytic leukemia treated according to the International Consortium on Acute Promyelo- cytic Leukemia 2006 protocol were ...the promyelocytic leukemia-retinoic acid ...
6
J. Braz. Chem. Soc. vol.27 número12
... In this study, we have isolated epimeric mixtures of the new (25R,S)-5α-spirostan-2α,3β-diol 3-O-β-D- glucopyranosyl-(1→4)-β-D-galactopyranosyl-(1→4)- β-D-galactopyranoside (1/2), (25R,S)-5α-spirostan- 2α,3β-diol ...
11
Yuni Wu, Youhua Xu, Yali Shen, Cuicui Wang, Gaili Guo and Tiantian Hu
... have been used in traditional Chinese medicine for the treatment of cancer. TMP has been synthesized and widely used in oriental medicine to effectively treat several cardio- vascular complications. Several studies have ...
11
J. Braz. Chem. Soc. vol.26 número6
... Tumor cell lines colorectal adenocarcinoma (HCT-116), ovarian carcinoma (OVCAR-8), human promyelocytic leukemia (HL-60) and glioma (SF-295), provided by the National Cancer Institute (Bethesda, MD, USA), ...
8