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Solid tumors

PD-L1 and Survival in Solid Tumors: A Meta-Analysis.

PD-L1 and Survival in Solid Tumors: A Meta-Analysis.

... different solid tumors is still ...inside tumors are more sensitive to anti-PD-1 therapy ...with tumors expressing high levels of PD-L1, especially when PD-L1 expressed on tumor-infiltrating ...

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Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.

Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.

... Unfavorable ratios between the number and activation status of effector and suppressor immune cells infiltrating the tumor contribute to resistance of solid tumors to T-cell based therapies. Here, we ...

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Activation of the PI3K/mTOR/AKT pathway and survival in solid tumors: systematic review and meta-analysis.

Activation of the PI3K/mTOR/AKT pathway and survival in solid tumors: systematic review and meta-analysis.

... Among solid tumors where targeted therapy has been developed against a known oncogene, presence of the oncogene has generally been associated with worse ...

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Fibroblast activation protein overexpression and clinical implications in solid tumors: a meta-analysis.

Fibroblast activation protein overexpression and clinical implications in solid tumors: a meta-analysis.

... In recent years, the close correlation between cancer and its microenvironment regarding tumor growth, invasion and metastasis has become increasingly apparent [1–3]. Strong experi- mental evidence has shown that stromal ...

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Prevalence of Café-au-Lait Spots in children with solid tumors

Prevalence of Café-au-Lait Spots in children with solid tumors

... Our study identified 28 children with multiple CALMs, 25 of which were associated with other congenital anomalies. The frequency of solitary CALMs was similar in the study groups 1 and 2 (children with solid ...

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Biomarkers as predictors of mortality in critically ill patients with solid tumors

Biomarkers as predictors of mortality in critically ill patients with solid tumors

... Biochemical markers produced by the affected organ or body in response to disease have gained high clinical value due to assess disease development and being excellent predictors of morbidity and mortality. The aim of ...

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Autologous stem cell transplantation for the treatment of pediatric solid tumors in Brazil

Autologous stem cell transplantation for the treatment of pediatric solid tumors in Brazil

... treating such patients. Sixty-three autologous HSCT were per- formed from August, 1994 to September, 2003; 80% of them were after 1999. Thirty-four patients were male (54%). The median age was 7 years (1 to 23). The ...

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Innovative delivery of siRNA to solid tumors by super carbonate apatite.

Innovative delivery of siRNA to solid tumors by super carbonate apatite.

... To further verify the in vivo efficacy of sCA, we conducted additional functional assays in the pre-established HT29 colon cancer model. Multiphoton microscopy revealed that the sCA- siRNA, but not the naked-siRNA ...

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Intensive chemotherapy as salvage treatment for solid tumors: focus on germ cell cancer

Intensive chemotherapy as salvage treatment for solid tumors: focus on germ cell cancer

... A particularity of GCTs is that the majority of patients can expect to be cured, even in the presence of metastatic disease (9). As most GCTs can be cured by chemotherapy, and in some cases by surgery alone, lessons ...

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The Prognostic Value of Decreased LKB1 in Solid Tumors: A Meta-Analysis.

The Prognostic Value of Decreased LKB1 in Solid Tumors: A Meta-Analysis.

... The current analyses have several important implications. First, decreased LKB1 may be a universal poor prognostic marker in solid tumors. In this meta-analysis, we included seven dif- ferent cancer types, ...

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The Human Bocavirus Is Associated with Some Lung and Colorectal Cancers and Persists in Solid Tumors.

The Human Bocavirus Is Associated with Some Lung and Colorectal Cancers and Persists in Solid Tumors.

... Figure 1. Sequence alignments of HBoV-specific PCR products from tumor tissue samples from lung and colorectal tumors. As reference sequences, the following GenBank accession number were used: ...

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Impact of metabolic resources and infiltrating immune cells on protective responses against solid tumors

Impact of metabolic resources and infiltrating immune cells on protective responses against solid tumors

... of tumors was detectable, these animals were sacrificed, and mammary tumors were carefully excised and ...the tumors were analyzed by flow ...

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A polymer-based magnetic resonance tracer for visualization of solid tumors by 13C spectroscopic imaging.

A polymer-based magnetic resonance tracer for visualization of solid tumors by 13C spectroscopic imaging.

... C-enriched polymer to overcome the low sensitivity of the 13 C nucleus rather than the hyperpolarization phenomenon. It is well recognized that macromolecules selectively extravasate into tumors because of the ...

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Sao Paulo Med. J.  vol.127 número1

Sao Paulo Med. J. vol.127 número1

... Since BMs induce higher rates of bone resorption, in addition to increased bone formation, evaluation of bone resorption markers in pa- tients with solid tumors who are prone to develop BMs is of interest. ...

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High prevalence of malnutrition among patients with solid non-hematological tumors as found by using skinfold and circumference measurements

High prevalence of malnutrition among patients with solid non-hematological tumors as found by using skinfold and circumference measurements

... with solid tumors presented greater deficits than did those with hematological malignancy diseases, but statistical differences were observed only for z-score, TSFT and AMC, with a low degree of association ...

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Tratamento da mucosite em pacientes submetidos a transplante de medula óssea: uma revisão sistemática

Tratamento da mucosite em pacientes submetidos a transplante de medula óssea: uma revisão sistemática

... with solid tumors undergoing high- dose chemotherapy with autologous peripheral blood stem cell transplantation rescue: a double blind, randomized, placebo-controlled ...

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Int. braz j urol.  vol.42 número3

Int. braz j urol. vol.42 número3

... an important subgroup due to their risk of malig- nancy, which ranges from 16–100% and 90–100%, respectively (16). The current standard of care for both Bosniak III and IV lesions is surgical treat- ment. Because of ...

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The neuropeptide alpha-melanocyte-stimulating hormone is critically involved in the development of cytotoxic CD8+ T cells in mice and humans.

The neuropeptide alpha-melanocyte-stimulating hormone is critically involved in the development of cytotoxic CD8+ T cells in mice and humans.

... observe solid tumors in wt mice after injection of these cell numbers (Figure 4C) indicating that a-MSH/MC-1R signaling plays an important role for anti-tumoral immune responses in vivo by ...

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A TNM Staging System for Nasal NK/T-Cell Lymphoma.

A TNM Staging System for Nasal NK/T-Cell Lymphoma.

... months, with 1- and 3-year OS rates of 15% and 4%, respectively. The survival time of the unique long-term survivor lasted for 36.9 months by the time of the last follow-up, while this patient had two lesions in the ...

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