tight junction
Expression of Tight Junction Proteins and Cadherin 17 in the Small Intestine of Young Goats Offered a Reduced N and/or Ca Diet.
... of tight junction (TJ) and adherens junction (AJ) proteins in intestinal epithelia were examined on mRNA level by qPCR and on protein level by western blot ...
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The PIKfyve inhibitor YM201636 blocks the continuous recycling of the tight junction proteins claudin-1 and claudin-2 in MDCK cells.
... even after 2 hr of incubation. A similar result was also seen after inhibition of ESCRT function [10]. These results emphasise the different trafficking itineraries that junctional proteins may undertake in epithelial ...
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Genetic analysis of genes related to tight junction function in the Korean population with non-syndromic hearing loss.
... Tight junctions (TJs) are essential components of eukaryotic cells, and serve as paracellular barriers and zippers between adjacent tissues. TJs are critical for normal functioning of the organ of Corti, a part of ...
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Expressions of tight junction proteins Occludin and Claudin-1 are under the circadian control in the mouse large intestine: implications in intestinal permeability and susceptibility to colitis.
... circadian clock regulated intestinal permeability although the precise mechanisms remain largely unknown [10]. The current study demonstrated that the expressions of TJ proteins Occludin[r] ...
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Hypoxia-induced hyperpermeability of rat glomerular endothelial cells involves HIF-2 a mediated changes in the expression of occludin and ZO-1
... of tight junction proteins and permeability alterations in rat glomerular endothelial cells (rGENCs) under hypoxia ...and tight junction proteins (occludin and ZO-1) in rGENCs were examined ...
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Escherichia coli STb enterotoxin dislodges claudin-1 from epithelial tight junctions.
... Mechanisms underlying the perturbation of the epithelial barrier are numerous. Some compounds directly interact with single TJ proteins [51], whereas others disturb barrier function by a general modification of TJ ...
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TGFβs modulate permeability of the blood-epididymis barrier in an in vitro model.
... the tight junction proteins claudin- 1 and occludin after TGFb treatment from different sides In order to test if the distinct side-specific TGFb effects on TER correspond to tight junction ...
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Bioinspired polyethersulfone-based hollow fiber membranes as the scaffolds in renal assist device for protein-bound toxins removal from blood
... expressed tight junctions which indicates functional ...microscope, tight junction formation pattern only in some regions repeats chicken wire-like structures indicating the formation of the contacts ...
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Tick-borne encephalitis virus replication, intracellular trafficking, and pathogenicity in human intestinal Caco-2 cell monolayers.
... We found that TBEV infected and replicated efficiently in human intestinal epithelial cells. The Caco-2 cell model, if grown for 3 weeks, is a suitable infection model for the small intestine, because it develops small ...
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Exogenous HIV-1 Nef upsets the IFN-γ-induced impairment of human intestinal epithelial integrity.
... Methodology/Principal Findings: We used unstimulated or IFN-c-stimulated Caco-2 cells, as a model for homeostatic and inflamed gastrointestinal tracts, respectively. We investigated the effect of exogenous recombinant ...
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Tumor necrosis factor alpha increases epithelial barrier permeability by disrupting tight junctions in Caco-2 cells
... The objectives of this study were to determine the effect of tumor necrosis factor alpha (TNF-α) on intestinal epithelial cell permeability and the expression of tight junction proteins. Caco-2 cells were ...
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Cerebrovascular and Blood-Brain Barrier Impairments in Machado-Joseph Disease
... Figure 3.5 – Expression levels of tight junction (TJ)-associated proteins in the cerebellum of MJD mice differ from wild-type controls. A) Schematic representation of TJ stru[r] ...
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Pulmonary permeability assessed by fluorescent-labeled dextran instilled intranasally into mice with LPS-induced acute lung injury.
... Tight and adherens junctions are intercellular junctions that are crucial for epithelial adhesion and barrier functions in a wide variety of tissues and organs [15,16]. A vital consequence of ALI is the disruption ...
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The role of adhesion molecules as biomarkers for the aggressive prostate cancer phenotype.
... of tight junction (Occludin, ZO-1, Claudin 1, Claudin 7) and adherence junctions (a- catenin, b-catenin and E-cadherin) in prostate cancer cell lines from localised (CAHPV-10) and different metastatic sites ...
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Tight regulation of unstructured proteins: from transcript synthesis to protein degradation
... addition, tight regulation of signalling and regulatory IUPs could minimize the potentially harmful effects of ectopic interactions and may provide robustness to signalling processes by ensuring that such proteins ...
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Selective remodeling: refining neural connectivity at the neuromuscular junction.
... shows that, in response to changes in growth and/or activity, the addition of new synaptic connections with the muscle cell involves significant production of presynaptic debris and ghos[r] ...
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Estudo teórico das propriedades estruturais, eletrônicas e reatividade de clusters...
... A linha vermelha indica os resultados para as conőgurações de mais baixa energia (LOW) usando funções de base Tight Tier2 , a linha azul indica os resultados para as conőgurações de mais[r] ...
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Drosophila Cbp53E Regulates Axon Growth at the Neuromuscular Junction.
... The Drosophila larval neuromuscular junction is a well-characterized model of neuronal devel- opment [44]. Since Cbp53E is localized to at least one class of NMJs we wanted to determine whether loss of function of ...
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Análise da recuperação em reservatório de gás com baixa permeabilidade (TIGHT GAS) através do fraturamento hidráulico
... O mercado norte-americano vem sendo a região de maior avanço na exploração, desenvolvimento e produção de reservatórios não convencionais, tendo a nova produção reduzido muito o preço do gás americano. O shale gas (gás ...
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Simulation of Triple Junction Motion with Arbitrary Surface Tensions
... to model triple junctions. Here, ε > 0 is a small parameter and W is a well potential, a non-negative function which has three minima for the three-phase case. This so-called phase- field method represents the phase ...
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