Top PDF A CASE OF PRIMARY UTERINE LYMPHOMA

A CASE OF PRIMARY UTERINE LYMPHOMA

A CASE OF PRIMARY UTERINE LYMPHOMA

ABSTRACT: A post menopausal lady presented with lump lower abdomen and bleeding per vaginum. USG revealed diffuse enlargement of the uterus. On hysterectomy, a grossly enlarged uterus with cystic left ovary were found. Hysterectomy was done and uterus with bilateral adnexa submitted for histopathological examination. Microscopic examination of the body of uterus revealed sheets of small lymphoid cells were found to replace the endo- and myo-metrium. These cells have small nuclei with clumped chromatin, and no prominence of nucleoli. They are not forming lymphoid follicles or germinal centers. Similar lymphoid cells were also found in the left ovary admixed with ovarian stroma. On IHC these cells were found to be CD
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Radiol Bras  vol.45 número3

Radiol Bras vol.45 número3

The objective of this paper was to present a case of lymphoma of uterine cer- vix, with emphasis on imaging findings which led to suspicion of the diagnosis, as well as the characteristics that differentiate this disease from epidermoid carcinoma of uterine cervix, that is the main differential diagnosis.

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A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma

A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma

Treatment of primary CNS lymphoma, as with other brain neoplasms, involves surgery, radiotherapy (RT), and chemotherapy (CT), with the latter two being the modalities of choice. The role of surgery is mainly diagnostic. How- ever, some recent studies have reported a better prognosis in radical surgical removal of single lesions in non-eloquent brain areas. The role of RT has lost importance in recent years. Holocranial RT achieves high response rates but the duration of the effect is short and neurotoxicity is high. CT is the first therapeutic choice for newly diagnosed primary lymphomas of the CNS. It allows for high response rates and long periods without symptoms. The most commonly used drug is high-dose methotrexate alone or in combina- tion with high-dose of cytarabine, procarbazine, vincristine and rituximab. A 2009 study reported a better response with methotrexate + cytarabine compared with methotrexate monotherapy. 2
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Radiol Bras  vol.45 número6

Radiol Bras vol.45 número6

In the literature, there is no evidence of relationship between primary bone lymphoma and osteochondroma or of coexistence of both of them in a single bone. The present report describes an uncommon case of primary bone lymphoma occurring simultaneously with osteochondroma in the proximal third of the tibia. In the present case, magnetic resonance imaging signs simulated the presence of sarcomatous degeneration.

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Arq. NeuroPsiquiatr.  vol.64 número2B

Arq. NeuroPsiquiatr. vol.64 número2B

ABSTRACT - The purpose of this study is to re p o rt a rare case of primary meningeal high grade Burkitt- type lymphoma presenting as the first clinical manifestation of acquired immunodeficiency syndrome. A 3 8 - y e a r-old Caucasian man, with a negative past medical history, sought treatment after experiencing glob- al headache for five days. CT-Scan revealed a right fro n t - t e m p o ro-parietal hyperdense subdural expansive mass. A craniotomy was performed and a hard white subdural was microsurgically dissected. Some hours after the surg e ry, the patient developed hemispheric cerebral edema and intracranial hypertension syn- d rome. Decompressive craniotomy was perf o rmed and the patient had an excellent re c o v e ry. Scre e n i n g blood tests diagnosed human immunodeficiency virus infection. Further investigation ruled out systemic diseases. Eleven days after the initial surgery, the patient developed an acute respiratory failure and sep- sis, dieing on that day. Pathological studies diagnosed Burkitt-type lymphoma.
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Fatal outcome in bronchus-associated lymphoid tissue lymphoma

Fatal outcome in bronchus-associated lymphoid tissue lymphoma

Primary pulmonary lymphoma is rare. The most common histological type is the bronchus-associated lymphoid tissue lymphoma. This type of lymphoma has an indolent course and excellent response to therapy. One-third of all cases are diagnosed incidentally. However, due to the rarity of this disease, little is known about its natural history in terms of dissemination and evolution. Herein, we report the unusual case of a 61-year-old man who refused treatment after being diagnosed with bronchus-associated lymphoid tissue lymphoma and died 2 years later from massive lung infiltration without dissemination to other organs.
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Rev. Hosp. Clin.  vol.57 número5

Rev. Hosp. Clin. vol.57 número5

Primary lymphoma of the liver is an extremely rare entity. A case of anaplastic large B-cell (both CD-20 and lambda positive) non-Hodgkin’s lymphoma that was confined to the liver in a 33-year-old man is reported. The patient was treated with an extended right hepatectomy and combination chemotherapy: cyclophosphamide, adriamycin, vincristine, and prednisone.

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Arq. NeuroPsiquiatr.  vol.69 número3

Arq. NeuroPsiquiatr. vol.69 número3

In a case of pineal gland lymphoma reported in the literature, the lesion appeared to be similar to primary tumors of pineal origin (pineocytoma and pineoblas- toma), or even to germinoma (which may also show an intermediate signal on T1 and hypointense signal on T2, due to a high nucleus/cytoplasm ratio) 1 . However, ger-

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PRIMARY EFFUSION LYMPHOMA OF PLASMABLASTIC TYPE: A RARE PRESENTATION IN AN  IMMUNOCOMPETENT MALE ADULT

PRIMARY EFFUSION LYMPHOMA OF PLASMABLASTIC TYPE: A RARE PRESENTATION IN AN IMMUNOCOMPETENT MALE ADULT

Concomitance of chronic diseases is another potential risk factor. A diagnosis of pleural PEL is initially based on excluding the possibility of other lymphoproliferative diseases that affect the pleural cavity and result in pleural effusion. In order to eliminate the possibility of secondary involvement of the pleural cavity caused by lymphoma, it is recommended that computed tomography scans of the neck, chest and abdomen be performed in order to locate enlarged lymph nodes or organomegalies, and that a blood count and fine-needle aspiration bone marrow biopsy be performed to investigate medullary infiltration. In this case, after these complementary tests, no enlarged lymph nodes, organomegalies or extranodal masses were found, nor was there any involvement of bone marrow or peripheral blood.
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Linfoma não Hodgkin primário da coluna vertebral.

Linfoma não Hodgkin primário da coluna vertebral.

Primary bone lymphoma (PBL) is an extremely rare condition, commonly confused with other primary bone injuries. It accounts for approximately 3-5% of all malignant bone tumors and 4-7% of all extranodal non-Hodgkin's lymphomas. It is characterized by the involvement of one or multiple bone locations, with or without the involvement of regional lymph nodes and viscera. Histo- pathologically, diffuse large-B-cell lymphomas account for the majority of cases of PBL. Long bones are usually involved, with the femur being the most commonly affected site. Pelvic bones and the vertebral column can also be involved. We report on a rare case of PLB of the vertebra in a 41-year-old woman. Immuno- histochemistry examinations revealed CD20 and CD45 positive cells. She was diagnosed with primary diffuse large B-cell lymphoma presenting as a vertebral column tumor. The histopathologic analysis of the bone marrow did not show lymphoproliferative disorders. The patient was treated with a CHOP plus etoposide regimen. Systemic chemotherapy was followed by radiotherapy (total dose = 3600 cGy) in the thoracolumbar region. There was no evidence of recurrence in the 20-month follow up. Rev. Bras. Hematol. Hemoter.
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A Case of Conjunctival Melanoma Presenting  with Breast Metastasis

A Case of Conjunctival Melanoma Presenting with Breast Metastasis

Most breast masses arise from the breast. Metastasis to the breast is fairly un- common, but can occur in breast skin and parenchyma. In particular, leukemia and lung cancers, and MM may metastasize to the breast. Breast metastasis might be the first symptom or may occur during the course of other malignancies. Our case presented with a fixed mass in the upper-medial quadrant of her left breast dur- ing regular follow-up visits. The mean time to breast metastasis in patients with MM is 62 months (13-178). In our case this time was 48 months. In a case series with 7 patients hematological malignancies (Hodgkin lymphoma, non-Hodgkin lymphoma, and leukemia) were the leading cause of breast metastasis, whereas in only 1 case the cause was MM. In another case series of 15 MM patients with metastasis to the breast, the primary tumor was frequently localized to the up- per extremities and trunk. In a report of 250 conjunctival MM cases the mortality rate was significantly higher in patients with tumors >4 mm in vertical thickness. In another 45-case MM series tumors with a diameter >10 mm were associated with higher mortality rates. In our case the thickness of the tumor was 5 mm. In conclusion, histopathological evaluation should be mandatory in patients with known primary malignancies in order to differentiate new primary tumors, metas- tases, and benign tumors.
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Non-Hodgkin lymphoma of the bladder

Non-Hodgkin lymphoma of the bladder

Patients with bladder lymphomas can be divided into 3 groups, according to their clinical presentation: 1) primary cases in bladder, 2) cases occurring in bladder as a manifestation of systemic disease, and 3) secondary cases, with clinical history of malignant lymphoma recurring in bladder. In the latter case, the main sites of primary involvement are peripheral lymph nodes, bone marrow and spleen (2). The authors report the case of a 41-year old patient with secondary lymphoma of the bladder occurring 2 years after treatment for “non-Hodgkin” lymphoma, diagnosed by biopsy of cervical lymph node.
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PRIMARY CUTANEOUS FOLLICLE CENTER LYMPHOMA – A DIAGNOSIS TO CONSIDER

PRIMARY CUTANEOUS FOLLICLE CENTER LYMPHOMA – A DIAGNOSIS TO CONSIDER

ABSTRACT – Introduction: Follicular lymphoma is the most common B-cell lymphoma to occur as a primary tumor of skin. Case report: The case of a 69-year-old caucasian female patient, with a 1 year history of a painless nodule, lo- calized in the frontal region, which had been observed several times on urgency room. On examination, we observed a nontender nodule, 3x2 cm, localized in the frontal region with small papules at the periphery. Histopathologic exami- nation of a biopsy from the nodule was suggestive of follicular lymphoma. Immunophenotyping: CD20+, CD3-, CD5-, CD10+, Bcl2+ in rare cells. The patient was observed by Hematology/ Oncology and the staging was negative and a course of palliative chemotherapy with R-CHOP, followed by radiotherapy was given. During a follow-up of 6 months there wasn´t any evidence of recurrences. Conclusion: This case report intends emphasize the relevance of educate the doctors for the diagnosis of this disease.
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PDF EN Jornal Brasileiro de Pneumologia 4 21 english

PDF EN Jornal Brasileiro de Pneumologia 4 21 english

Primary pulmonary lymphoma is rare. The most common histological type is the bronchus-associated lymphoid tissue lymphoma. This type of lymphoma has an indolent course and excellent response to therapy. One-third of all cases are diagnosed incidentally. However, due to the rarity of this disease, little is known about its natural history in terms of dissemination and evolution. Herein, we report the unusual case of a 61-year-old man who refused treatment after being diagnosed with bronchus-associated lymphoid tissue lymphoma and died 2 years later from massive lung infiltration without dissemination to other organs.
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PRIMARY CUTANEOUS LARGE B CELL LYMPHOMA OF THIGH: A CASE REPORT

PRIMARY CUTANEOUS LARGE B CELL LYMPHOMA OF THIGH: A CASE REPORT

Epidermis showed ulceration with absence of epidermotropism. Dermis showed dense lymphocytic infiltration. Lymphoid cells consists of small round cells separated by thick collagen bundles with few large cells. The cells showed uniform round vesicular nucleus with scanty cytoplasm. Occasional mitosis was noted. Eosinophils and neutrophils were also seen.(Fig. 3)

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Successful Treatment of Disseminated Fusariosis with the Combination of Voriconazole and Liposomal Amphotericin B

Successful Treatment of Disseminated Fusariosis with the Combination of Voriconazole and Liposomal Amphotericin B

5. Chu L, Mao W, Curran Vikramsingh K, Liu X, Qiu HM, Zheng JH, Wang Y, Yu GP, Xu Q. Primary malignant lymphoma of the glans penis: a rare case report and review of the literature. Asian J Androl 2013;15:571-572. 6. Karki K, Mohsin R, Mubarak M, Hashmi A. Primary Non-Hodgkin’s

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Primary esophageal lymphoma.

Primary esophageal lymphoma.

We describe the case of a 54 year old woman seen with an esophageal mass diagnosed as a primary esophageal lymphoma. The main symptom was dysphagia of seven months duration. The treatment consisted in resection of the tumor, and reconstruction of the defect with a reversed pleural flap, followed by a chemotherapy regimen that consisted of five drugs, cyclophosphamid, prednisone, doxorubicin, rituximab and vincristine (R-CHOP). The patient developed an esophageal pleural fistula treated with pleural drainage and irrigation that closed in 45 days. Two and one half years later she is doing well and disease free.
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Modeling and Analysis of Queuing Systems in Banks A case study of Ghana Commercial Bank Ltd. Kumasi Main Branch

Modeling and Analysis of Queuing Systems in Banks A case study of Ghana Commercial Bank Ltd. Kumasi Main Branch

Data for this study was collected from the banking hall of Ghana Commercial Bank (GCB) Ltd. Kumasi Main Branch. The methods used during the data collection were direct observation and personal interview and questionnaire administering. The data gathered were the daily record of queuing system over a month. The variables measured included arrival and service rate per hour. They were analyzed for simultaneous efficiency in customer satisfaction and economic cost minimization through the use of a multi-channel single-line queuing model, which were compared for a number of queue performances such as; the average number of customers in the queue and in the system, average time each customer spends in the queue and in the system and the probability of the system being idle. The following assumptions were made for modeling the queuing system at Ghana Commercial Bank (GCB) Ltd. Kumasi Main Branch.
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Nonepitheliotropic lymphoma in a dog: case report

Nonepitheliotropic lymphoma in a dog: case report

Cutaneous lymphoma is an uncommon neoplasm in dogs and Boxer, Shih Tzu, Cocker Spaniel, Basset Hound and Golden Retriever are predisposed breeds. This report describes the case of a 5-year-old mixed-breed female dog presenting ulcerated and fast-growing skin nodules. Initial cytology revealed a poorly differentiated round cell neoplasm. Excision of nodules was performed due to the emergence of new lesions. Histopathological examination was suggestive of histiocytoma. The lesions recurred after one year, and a surgical excision of nodules was performed. An immunohistochemical examination was carried out to refine the diagnosis, revealing positivity for CD3 markers in neoplastic cells and for HLA-DR in neoplastic lymphoid and reactive histiocytic cells; these findings, coupled with the morphological findings, were compatible with nonepitheliotropic cutaneous T-cell lymphoma. Its etiology has not yet been fully elucidated; however, recurrent skin inflammation may be a predisposing factor, which leads to chronic lymphocytic proliferation. Cutaneous lymphoma (CL) causes nonspecific lesions and its classification as epitheliotropic and nonepitheliotropic (NEL) throughout cutaneous signs is difficult, with NEL being the least described form. Animals affected by this form of lymphoma have lymphadenomegaly, firm and multiple nodules that can extend from the dermis to the subcutaneous layer, alopecic and/or ulcerated, often in chest, head and extremities, with rapid progression, which was compatible with the present case. Definitive diagnosis of CL is obtained through histopathology and immunohistochemistry. The aim is to report a case of nonepitheliotropic cutaneous lymphoma in a dog, with emphasis on its clinical, histopathological, and immunohistochemical aspects.
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Tumores hepáticos incomuns: ensaio iconográfico – Parte 2

Tumores hepáticos incomuns: ensaio iconográfico – Parte 2

CT usually demonstrates a hypodense mass with periph- eral, heterogeneous enhancement, with a poorly vascularized central area. Compressive effects of the mass may occur, de- termining dilatation of the biliary tract and portal hyperten- sion (Figure 3). MRI is one of the best methods capable of better characterizing an inflammatory tumor. A focal, mass- type lesion is the most common appearance and presents with low signal intensity on T1-weighted images and slightly in- creased signal on T2-weighted images, sometimes with in- termingled foci of marked hypersignal. After paramagnetic contrast media injection, intense and heterogeneous enhance- ment is observed, particularly in the periphery of the lesion (8) .
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