[PDF] Top 20 THE ROLE OF ANTIGEN PRESENTING CELLS IN IMMUNE REGULATION MEDIATED BY REGULATORY T CELLS
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THE ROLE OF ANTIGEN PRESENTING CELLS IN IMMUNE REGULATION MEDIATED BY REGULATORY T CELLS
... anaesthetized by an initial intraperitoneal injection of 50 mg/kg ketamine, 10 mg/kg xylazine, and 4 mg/kg acepromazine, and the PLN was prepared microsurgically for intravital microscopy as ... See full document
138
Alterations in regulatory T cells induced by specific oligosaccharides improve vaccine responsiveness in mice.
... effector T cells for 96 ...both the spleen as well as the MLN suppressed the CD3 induced T cell proliferation, in none of the ratios tested a difference ... See full document
9
Effect of immunoglobin-like transcript 7 cross-linking on plasmacytoid dendritic cells differentiation into antigen-presenting cells.
... dendritic cells (pDC) are immature lymphoid-derived DC which have the ability to capture and process ...Upon antigen capture, pDC migrate to the lymph nodes and mature into professional ... See full document
9
The origin of tumour-infiltrating regulatory T cells
... anti-cytotoxic T- lymphocyte-associated protein 4 (CTLA-4) [20]. Despite the initial favourable results in the clinics for inhibitors of these molecules, they have only been approved ... See full document
82
Cathepsin B in antigen-presenting cells controls mediators of the Th1 immune response during Leishmania major infection.
... Upon in vitro infection with Leishmania promastigotes, BMDC present poor cytokine expression ...levels of IL-12 (both p70 and p40 forms) than WT and Ctsl 2/2 BMDC in response to ...differences ... See full document
15
LPS nephropathy in mice is ameliorated by IL-2 independently of regulatory T cells activity.
... protective role of Tregs in experimental nephropathy induced by LPS that is a model of transient proteinuria associated with foot process effacement, resembling human minimal change ... See full document
9
SA-4-1BBL costimulation inhibits conversion of conventional CD4+ T cells into CD4+ FoxP3+ T regulatory cells by production of IFN-γ.
... Treg cells play a critical role in peripheral tolerance to ...alterations in their function or numbers are associated in immune abnormalities ranging from autoimmunity to ... See full document
8
Immune reconstitution inflammatory syndrome and the influence of T regulatory cells: a cohort study in The Gambia.
... responses of a variety of immune cell types [18–19] in response to microbial and self-antigens ...analyzing the role of Tregs in IRIS conducted using a cross- ... See full document
8
Continuous activation of the CD122/STAT-5 signaling pathway during selection of antigen-specific regulatory T cells in the murine thymus.
... observed in mice doubly-deficient for IL-2 and IL-15 (a cytokine that share CD122 and CD132 with IL-2) [20], suggesting that foxp3 expression in the thymus of IL-2-KO animals observed ... See full document
8
The effect of CpG-ODN on antigen presenting cells of the foal
... for the recognition of highly conserved structural motifs (pathogen-associ- ated molecular patterns or PAMPS) only expressed by microbial ...pathogens. The combination of different TLRs ... See full document
17
Cord blood derived CD4+ CD25(high) T cells become functional regulatory T cells upon antigen encounter.
... suppressive regulatory functions upon re-exposure result- ing in tolerance to environmental ...is in line with shift in the paradigm from allergen avoidance direction exposure in ... See full document
8
Regulation of Exacerbated Immune Responses in Human Peripheral Blood Cells by Hydrolysed Egg White Proteins.
... Despite the apparent opposite effects of Th2 and Th1 immunity, there are examples of antioxidant and anti-inflammatory compounds that decrease the effects mediated by IFN-γ and ... See full document
15
The repertoire and specificity of follicular regulatory T cells
... antibodies immune action is in their secreted form, they can also be produced as a membrane-bound receptor – the ...constituted by two heavy chains (H-chains) and two light chains (L-chains) ... See full document
196
homeostasis of the IL-2-producing CD4 T cells and theirrole in the control of T regulatory cells function and number.
... + T cells typically make up about 5-10% of the peripheral CD4 + T cell pool in humans and mice and are characterised by expression of Foxp3 ...These cells ... See full document
174
Elucidating the role of macrophages and CD4+CD25+ regulatory T cells on colorectal cancer cell invasion
... infiltration of Tregs into tumours has been reported to be associated with an unfavourable outcome in several human cancers, such as ovarian 119 , breast, gastrointestinal, lung, liver, pancreatic cancer ... See full document
79
To investigate the necessity of STRA6 upregulation in T cells during T cell immune responses.
... required in immune responses [13–18,36]. It is reported that in hepatocytes, holo-RBP triggers STRA6, leading to the activation of JAK2/STAT5 signaling pathway, which is also essential ... See full document
13
Prolonged acceptance of skin grafts induced by B cells places regulatory T cells on the histopathology scene
... study the immune response of an nB cell-treated animal, 1 week after nB cell injection the animals were immunized in the footpad and 1 week later draining lymph nodes (DLN) were ... See full document
7
Regulatory T cells in elderly patients with asthma
... to the acquisition of suppressive ability [34,35]. The group of elderly asthmatic patients studied had increased values of CD3CD4CD25 high CD127 and CD3CD4CD25 high CD127 high ... See full document
8
The role of regulatory T cells in the control of B cell mediated immune responses
... is the critical cytokine promoting Foxp3 upregulation in iNKT cells, as described for CD4 + T cell conversion into Foxp3 + Treg cells ...advantage of the TGF-b–rich ... See full document
150
T follicular regulatory cells in human adaptive immunity and autoimmunity
... governed by intraclonal competition for an antigen-specific niche, suggesting that antigens themselves are likely to be rare and tissue specific 172,177 ...drives the thymic selection of Treg ... See full document
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