[PDF] Top 20 Assessing the impact of alternative splicing in thyroid cancer
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Assessing the impact of alternative splicing in thyroid cancer
... to the complexity of configuring an iRAP experiment, a user friendly web interface was designed to allow the creation of said experiments and the retrieval of ...results. ... See full document
77
Analysis of the contribution of alternative splicing to glioma subtype definition
... is the most aggressive glioma type known, characterized by a high capacity to invade the surrounding tissue, high proliferation rates, abundant vascularization and a large amount of necrotic ...by ... See full document
114
Thyroid cancer burden and economic impact on the Brazilian public health system
... overuse of resources, health systems in different countries are reconsidering the usefulness of neck ultrasound to screen for thyroid cancer in asymptomatic ... See full document
8
Impact of historic histopathologic sample review on the risk of recurrence in patients with differentiated thyroid cancer
... limitation of this study is the low number of patients in each RR group, which could have limited the statistical ...SIR in the low risk groups and 6.3 and 20% SIR ... See full document
7
A statistical method for the detection of alternative splicing using RNA-seq.
... shown in Figure S2 and Table S1, non-specific mapping to exon junctions is a big problem for ...RNA-seq. In mouse dataset, 4,102,511 reads were mapped to ESJ, while 929,756 reads were mapped to negative ... See full document
8
An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype.
... collection. The specimens were sectioned as usual at ...visualize the lesion of ...smears in Figure 5 and Figure S5. A small number of other cell types may also be present, most ... See full document
21
Epigenetics and alternative splicing
... regulators of mRNA ...one of potentially many isoforms. Alternative splicing and editing contribute to the increasing gene isoform diversity (Geisler & Coller ...influence ... See full document
78
Small molecule amiloride modulates oncogenic RNA alternative splicing to devitalize human cancer cells.
... [38]. The extensive serine phosphorylation of the RS domain is also important for regulating the activities and localization of SR proteins ...involved in the ... See full document
13
Impact of Telegenetics and Alternative Models of Care on Hereditary Cancer Genetic Counseling in British Columbia
... completed in 2005 involved patients in six BC com- munities in the North and Interior ...total of 67 patients were invited to partici- pate in the study and 43 ... See full document
21
Anaplastic thyroid cancer
... presented in Table 1. Of the 33 ...(R0) in 4 (12.5%), microscopic (R1) in 12 ...(R2) in 10 (31.3%). Surgical margins did not have impact on survival: estimated median ... See full document
13
A new twist to ibuprofen: alternative action in alternative splicing
... cancers in the gastrointestinal tract, our understanding of the molecular mechanisms underlying the antineoplastic activity of ibuprofen is still ...to the COX- ... See full document
8
A Computational Platform for Assessing the Impact of Alternative Splicing in Cancer
... obtain the whole human genome, one first splits it into pieces which are then sequenced and reassembled in the original order to get to the original ...because of incorrect reads from ... See full document
82
Bioinformatics application for analysis and visualisation of alternative splicing in cancer
... de splicing alternativo a partir de grandes con- juntos de dados transcript´omicos provenientes do projecto The Cancer Genome Atlas ...de splicing alternativo ...de splicing alternativo ... See full document
105
The impact of thyroid cancer and post-surgical radioactive iodine treatment on the lives of thyroid cancer survivors: a qualitative study.
... improvement in knowledge translation about adjuvant radioactive iodine to individuals being offered this ...treatment. In terms of future research and care directions, the desire for more ... See full document
8
Regulation of the alternative splicing of RAC1b in tumour cells
... member of a subfamily of ubiquitously expressed hnRNPs and contains four RNA recognition motif (RRM) domains that bind to the polypyrimidine track of mRNAs introns (Oberstrass ...between ... See full document
64
Assessing the impact of alternative splicing in cancer
... use the specific domain problem of assessing the impact of alternative splicing in cancer as a use and test case by automating the full process ... See full document
68
Anaplastic thyroid cancer
... effect in disease re- occurrence, with half of the patients relapsing when treated with radiotherapy alone (Small- ridge and Copland, ...to the recur- rence rate, cytotoxic agents such as ... See full document
13
Width of gene expression profile drives alternative splicing.
... involved in more cellular functions and expressed in more tissues than MS genes (Figure 2), which could result from the fact that alternative splicing variants of widely ... See full document
13
Alternative promoters influence alternative splicing at the genomic level.
... exon. The number of APs is independent of the number of transcripts per exon for human genes (A) and mouse genes (B), ...respectively. The number of transcripts covering a ... See full document
8
Assessing the impact of a missed mass drug administration in Haiti.
... rounds of MDA (2000–2005), antigen prevalence had decreased signifi- cantly, from nearly 50% to ...reduction in microfilare- mia from 15% to ,1% ...rounds of MDA, it was evident that additional ... See full document
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