[PDF] Top 20 BRCA1: a novel prognostic factor in resected non-small-cell lung cancer.

... early-stage non-small-cell lung cancer (NSCLC) is considered a potentially curable disease following complete resection, patients have a wide spectrum of survival according to stage ... See full document

... increase in platelet count may promote tumor cells growth and ...growth factor (VEGF) and platelet- derived growth factor (PDGF), during blood ...role in regulating angio- genesis. The ... See full document

... needed. In addition, an important issue that needs to be taken into account is the type of adjuvant therapy that each patient received because chemother- apy and/or therapies that target the epidermal growth ... See full document

... difference in outcome among patients with the same clinical stage of the disease suggests that advanced NSCLC is a heterogeneous disease and the survival depend of some patients characteristics as anemia, platelet ... See full document

... Recently study revealed that CEA level change during EGFR-TKIs therapy can be used to a predictor of survival.[22] However, LMR change (MBR) during EGFR-TKIs was seldom men- tioned before. Our study revealed patients ... See full document

... increase in the incidence of lung cancer in women in re- cent years, it has brought broad concerns with its unique clinical and epidemiological characteristics and beter ...advanced ... See full document

... up-regulated in our study were MARS, MRPL3, PABPC1 and ...catalyst in the binding of methionine to its corresponding ...reported in human colon cancer ...shown in breast cancer ... See full document

... ushered in a new era with respect to the treatment of advanced non-small-cell lung ...growth factor receptor tyrosine kinase inhibitors (eg, gefitinib, erlotinib, and afatinib) ... See full document

... Lung cancer remains the most dominant cause of cancer-related death in spite of advances in treatment strategies ...seen in patients within the same ...more novel ... See full document

... as prognostic markers of 3-month survival after diagnosis of stage IV non-small cell lung cancer ...a cancer treatment center in southern Brazil between January of ... See full document

... was prognostic of inferior survival. In addition, our optimal cutpoint analysis suggests that there is a clear threshold ...5.1% in squamous cell ...reported in other manuscripts ... See full document

... useful in patients with an increased pre-treatment level ...reduction in serum concentration during a therapy but was not a sign for disease remission [31] and thymidine kinase was unable to discriminate ... See full document

... only in full ...included in the article directly or calculated from the survival ...inaccuracy in the extracted survival ...strategies in these studies have different impact on overall ... See full document

... cohort. The optimal cut-off points were found out from ROC curve which is now widely recog- nized as the best approach for measuring the quality of diagnostic system. To ensure the best accuracy and diagnostic effect, ... See full document

... growth factor receptor (EGFR), member of the human epidermal growth factor receptor (HER) family, plays a critical role in regulating multiple cellular processes including proliferation, ... See full document

... resection in patients with stage I ...prognoses. In addition, patients with both pre-operative hypoalbuminemia and post-operative hypoal- buminemia had worse ...independent prognostic factors for RFS ... See full document

... isoform in different type of cancer cells or tissues are variable, suggesting the contribution or biological importance of each TRPC isoform in different cancer type could be ...negative ... See full document

... implicated in relevant biological processes (according to gene ontology) in lung ...down-regulated in adenocarcinoma, are involved in several critical cell functions such as ... See full document

... Uma análise do estadiamento internacional para o câncer do pulmão, utilizado mundialmente nos últimos dez anos, mostrou problemas em duas áreas. O primeiro problema diz respeito ao mapa dos linfonodos mediastinais criado ... See full document

... oligoprogression), in which the central nervous system (CNS) or other extra-CNS sites may be the main locations of progression ...(64). In sites such as the brain and bone, local therapy options (surgical ... See full document