[PDF] Top 20 CHRNA5 polymorphism and susceptibility to lung cancer in a Chinese population
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CHRNA5 polymorphism and susceptibility to lung cancer in a Chinese population
... Polymorphisms in the nicotinic acetylcholine receptor subunit CHRNA5 gene have been associated with lung cancer positive susceptibility in European and American ... See full document
6
Genetic variants in MUC4 gene are associated with lung cancer risk in a Chinese population.
... kb in size and is located on chromosome 3 in region q29 ...[30]. To identify SNPs that were related to lung cancer, we first selected 296 of MUC4 SNPs with minor allele ... See full document
11
Identification of a comprehensive spectrum of genetic factors for hereditary breast cancer in a Chinese population by next-generation sequencing.
... mutations in our study. However, to date, three FA genes (FANCD1, FANCN, FANCJ) have been shown to be bona fide breast cancer susceptibility ...breast cancer risk has not ... See full document
20
Potentially functional polymorphism in IL-23 receptor and risk of acute myeloid leukemia in a Chinese population.
... lance and promote de novo carcinogenesis and tumor neovascular- ization ...[16–18]. In contrast, other groups have shown that IL-23 exerts antitumor activity through stimulation of T cells and ... See full document
5
The DNA repair gene APE1 T1349G polymorphism and risk of gastric cancer in a Chinese population.
... Intestinal and diffuse types have different epidemiology and ...gastric cancer is international variation and predominates in high-risk geographic areas, especially in Japan, ... See full document
5
TERT-CLPTM1L Rs401681 C>T polymorphism was associated with a decreased risk of esophageal cancer in a Chinese population.
... rs401681 polymorphism and cancer have been published, with inconsistent results ...2,396 lung cancer cases and 3,001 controls showed that the CLPTM1L T allele was associated with ... See full document
7
A functional polymorphism C-509T in TGFβ-1 promoter contributes to susceptibility and prognosis of lone atrial fibrillation in Chinese population.
... C-509T polymorphism and AF risk was estimated by computing odds ratios (ORs) and their 95% confidential intervals (CIs) from multivariate logistic ...difference in luciferase activity was also ... See full document
9
A TagSNP in SIRT1 gene confers susceptibility to myocardial infarction in a Chinese Han population.
... SNPs in SIRT1 gene have been widely studied in other traits (S1 Table), there is no published paper reporting the direct effects of these three tagSNPs on MI risk ...obesity in Belgian Caucasians ... See full document
12
A Non-Synonymous Single Nucleotide Polymorphism in the HJURP Gene Associated with Susceptibility to Hepatocellular Carcinoma among Chinese.
... htSNPs in the HJURP gene locus with the risk of occurrence of HBV-related HCC in two Chinese case-control ...NP_060880.3) in exon 8 of the HJURP gene was significantly associated with the ... See full document
15
N-acetyltransferase 2 polymorphisms and risk of esophageal cancer in a Chinese population.
... analyses in these studies. In the esophagus, the slow NAT2 acetylator genotype was more susceptible to esophageal cancer in Japan ...However, in another study in Taiwan, ... See full document
7
Genetic polymorphism of NOS3 with susceptibility to deep vein thrombosis after orthopedic surgery: a case-control study in Chinese Han population.
... region, and c.894G/T corresponds to glutamic acid and aspartic acid at position 298 of eNOS protein, ...compared to that with glutamic acid [16]. As a result, the T allele may result in ... See full document
5
Interactions between environmental factors and melatonin receptor type 1A polymorphism in relation to oral cancer susceptibility and clinicopathologic development.
... rs13140012, and rs6553010) alone did not contribute to oral-cancer ...chewing and cigarette smoking) and MTNR1A gene polymorphisms on the risk of oral cancer are well ...Similar ... See full document
13
Association between the c.910A.G genetic variant of the XRCC1 gene and susceptibility to esophageal cancer in the Chinese Han population
... ,q13.3, and has 17 exons. The XRCC1 protein plays a critical role in the repair of single- strand DNA breaks and in the DNA base excision repair pathway ...expression and function of ... See full document
5
Replication and fine mapping for association of the C2orf43, FOXP4, GPRC6A and RFX6 genes with prostate cancer in the Chinese population.
... close to two genes, GPRC6A and ...GPRC6A in normal conditions ...expressed in the Leydig cells of the testis, and mice deficient in Gprc6a show male feminization and a ... See full document
6
IL23R gene confers susceptibility to ankylosing spondylitis concomitant with uveitis in a Han Chinese population.
... factors and immune responses ...responses and the progression of ...IL8, and tumor necrosis factor-a and that it regulates the amplification and the stability of Th17 lymphocytes ... See full document
5
CYP1A1 Ile462Val polymorphism contributes to lung cancer susceptibility among lung squamous carcinoma and smokers: a meta-analysis.
... cases and controls, however only ten eligible publications provided non-smokers ...found to be associated with the CYP1A1 exon 7 gene polymor- phisms and lung cancer risk in ... See full document
11
Association between XPD (Lys751G1n) Polymorphism and Lung Cancer Risk: A Population-Based Study in Iran
... chance to treat lung cancer is so low because of the prognosis of the disease in late stages (me- ...this cancer and its related genotype states is of great importance for the ... See full document
6
Association between tumor necrosis factor alpha rs1800629 polymorphism and risk of osteoarthritis in a Chinese population
... rs1800629 polymorphism was associated with OA risk among Caucasian populations. To examine the role of this candidate gene in Asian populations, we conducted a hospital-based case-control study ... See full document
7
Interaction between GSTP1 Val allele and H. pylori infection, smoking and alcohol consumption and risk of gastric cancer among the Chinese population.
... those in western people, such as European–Americans (33%) and African–Americans (42%) ...that, in our study, genotype frequencies among the population fitted the Hardy–Weinberg law further ... See full document
7
Contributory role of five common polymorphisms of RAGE and APE1 genes in lung cancer among Han Chinese.
... RAGE and APE1 in lung carcinogenesis remains to be ...with lung cancer. In a previous study by Schenk et al [9], a promoter polymorphism (T-388A) in RAGE ... See full document
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