[PDF] Top 20 EZH2 depletion blocks the proliferation of colon cancer cells.
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EZH2 depletion blocks the proliferation of colon cancer cells.
... transcription of 1 m g RNA was perfor- med by using the oligo-dT primer and ProtoScript M-MuLV Taq RT-PCR Kit (New England Biolabs, Frankfurt, Germany) according to the manufacturer’s ...using ... See full document
14
Hydrogen sulfide lowers proliferation and induces protective autophagy in colon epithelial cells.
... subject of intense investigation because of its role in various pathological states including ...time of stress and nutrient deprivation [7,10]. In colon cancer, extensive ... See full document
9
CoCl2, a mimic of hypoxia, induces formation of polyploid giant cells with stem characteristics in colon cancer.
... one of the most important pathological features of the solid tumors, because it is the result of an imbalance between proliferation of tumor cells and ... See full document
10
Curcumin induces human HT-29 colon adenocarcinoma cell apoptosis by activating p53 and regulating apoptosis-related protein expression
... growth of many human cancer cell lines in vitro (9). A number of mechanisms of cell proliferation inhibition and apoptosis induc- tion by curcumin have been ...demonstrated. The ... See full document
8
The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth.
... showed the typical signs of tumor morbidity at 16 weeks of age, as evidenced by overt anemia and cachexia, whereas APC min/+ mice overexpressing SIRT1 (SIRT1 DSTOP ) displayed no overt signs ... See full document
9
Keratin23 (KRT23) knockdown decreases proliferation and affects the DNA damage response of colon cancer cells.
... and Proliferation (1,8E-07, n = 47), Cellular Movement (3,2E-07, n = 25) and Cell Death (2E-05, n = ...was the only gene strongly affected in both ...decreased the expression of key ...for ... See full document
13
MicroRNAs Induce Epigenetic Reprogramming and Suppress Malignant Phenotypes of Human Colon Cancer Cells.
... DLD-1 colon cancer ...with the idea that miR-302 induces global DNA demethylation, on the DNA sequence level on each chromosome, compared to the mock experiment (Fig ...on the ... See full document
23
ISSN 0100-879X BIOMEDICAL SCIENCES AND CLINICAL INVESTIGATION
... on proliferation of neural stem cells in ...stem cells cultured in SFM containing EGF and bFGF divided asymmetrically to reproduce themselves and produced EGF-responsive progenitor stem ... See full document
9
Efeitos da polpa do fruto de annona crassiflora mart., nos parâmetros bioquímicos e na carcinogênese de colon de ratos
... effects of an ethanolic extract of marolo leaves on bone marrow ...in the same mouse bone marrow micronucleus ...anticarcinogenicity, the present work was performed to investigate, in vivo, ... See full document
7
Ursolic acid simultaneously targets multiple signaling pathways to suppress proliferation and induce apoptosis in colon cancer cells.
... binding of transactivators [20,21]. P300 is expressed in abundance in cancer cells and p300 overexpression augments COX-2 transcriptional activation ...bridge the promoter-bound ... See full document
13
Prostate Cancer: A State of The Heart
... speciically the patient underwent PLND and 14 nodes were removed, 3 of which were ...point the patient also sufered a myocardial infarction and was treated with a percutaneous coronary intervention ... See full document
6
A mathematical model of bimodal epigenetic control of miR-193a in ovarian cancer stem cells.
... lung cancer [18, 19]. Importantly, miR-193a targets the stem cell marker, c-KIT, for repression in AML [18, ...target of miR- 193a is E2F6 [21]. Up-regulation of E2F6 has been observed in ... See full document
17
Natural products as new antimitotic compounds for anticancer drug development
... After the first tubulin-binding agents showed antitumor effects, many other tubulin-targeting antimitotic drugs were developed, along with related inhibitors directed at other targets such as kinases and mitotic ... See full document
11
Mangiferina: em sistemas pectinaquitosana, metabolismo intestinal in vitro e atividade anticancer
... presence of polysaccharides used in the formulations was identified by FTIR as well as the bioactive mangiferin showing characteristics absorbance ...for the different particles obtained ... See full document
242
Potent anti-cancer effect of 3'-hydroxypterostilbene in human colon xenograft tumors.
... growth of cancerous cells throughout the body called ...[1]. The relationship between apoptosis and autophagy is complex and varies between cell types and different ...promoters of ... See full document
8
Utilizing ras signaling pathway to direct selective replication of herpes simplex virus-1.
... stability of cyclin ...drive the formation of active cyclin-D1–CDK4 (cyclin-dependent kinase-4) and cyclin-D1–CDK6 complexes, which promote cell-cycle progression by phosphorylating retinoblastoma ... See full document
9
Circular RNA hsa_circ_0000523 regulates the proliferation and apoptosis of colorectal cancer cells as miRNA sponge
... Among the novel class of endogenous long non-coding RNAs, circular RNA (circRNA) is known as a key regulator in the development and progression of different ...in the tumorigenesis ... See full document
10
The Impact of the Expansion of the Bolsa Familia Program on the Time Allocation of Youths And Their Parents Lia Chitolina Miguel Nathan Foguel Naercio Menezes-Filho
... household, the program caused an increase of more than 11 percentage points in the probability of attending ...in the estimated impact is the fact that his/her family is only ... See full document
39
MiR-493 suppresses the proliferation and invasion of gastric cancer cells by targeting RhoC
... handful of studies have identified specific miRNAs involved in human tumorigenesis and tumor progression , , ...towards the identification of relevant miRNAs but also to identify the specific ... See full document
7
Efficacy of the dietary histone deacetylase inhibitor butyrate alone or in combination with vitamin A against proliferation of MCF-7 human breast cancer cells
... for the control of cancer. In the present study, we investigated the effects of treatment with butyrate, a dietary HDACi, combined with vitamin A on MCF-7 human breast ... See full document
11
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