[PDF] Top 20 Gene-network analysis identifies susceptibility genes related to glycobiology in autism.

... Expression analysis during mouse brain development of glycobiology-related genes overrepresented in autism- associated ...expression in the interior of the medial ... See full document

... Duroc to Pietrain allele of origin) for significant eQTL were input into the Ingenuity Pathways Analysis software (Ingenuity Systems, Red- wood City, CA, USA) for further data mining of pathways subject ... See full document

... led to the development of two primary strategies for applying gene network-based analysis to genome- wide SNP ...associated genes or chromosomal regions, and any other ... See full document

... levels in Bassoon mutant mice and reduces epileptic seizures ...interconnection in epilepsy, corroborated in this ...arborization in CA1 pyramidal neurons and is a LG1L receptor ...expressed ... See full document

... ranked gene identified within shared dysregulated pathways can be used as diagnostic marker for ...integrated network approaches will provide a better understanding of the underlying disease mechanism and ... See full document

... There is growing evidence that genetic and chromo- somal factors are important in the genesis of autism spec- trum disorders. The most commonly reported cytogenet- ic abnormalities are deletions involving ... See full document

... able to induce LIG4 after IR but later than in WT. In addition, LIG4, KU70, KU80, and RAD50, are constitutively higher in atm ...likely in favor of Ku-dependent NHEJ before IR in ... See full document

... genetic susceptibility to obesity is well ...linked to a molecular ...SNPs in cellular phospholipid metabolism loci were reported by that ...utilized in genome-wide statistical ... See full document

... Wisconsin in the Biochemistry Department in accordance with NIH guidelines and the University of Wisconsin Research Animals Resource ...bred to obtain F1 ob/ob mice ...[53–54]. To restore ... See full document

... employed in sample selection. In the first stage, the three agricultural zones in the state were purposively ...Ohafia. In the second stage three local governments actively involved in ... See full document

... acids in cell membranes can affect cold adaptation in Drosophila [45], polyunsaturated fatty acids can also activate the Drosophila light- sensitive channels ...DGE analysis, we obtained 1,566 ... See full document

... the genes, the terms are defined a priori and constructed independently from the experimental ...annotating genes and transcripts, as well as for finding over- represented functional groups of genes ... See full document

... (CENTRAL) to identify available articles published up to August 2012 in which IL-10 polymorphisms were studied in asthma patients and ...and in combination with ‘polymorphism’ or ... See full document

... and in parallel in different domesticated cotton ...and in a second domesticated allopolyploid cotton, G. barbadense [59]. In addition, Hu et ...showed, in a recent, high- throughput ... See full document

... b-cells in the pancreatic ...appear to modulate individual disease susceptibility in patients and in animal models ...antigen-4 gene (CTLA4) and the gene encoding CD28 ... See full document

... Alterations in the overall variance in gene expression in peripheral blood lymphocytes are also of ...with autism have immunological abnormalities and it has been previously reported ... See full document

... processes in marine ectotherms ...(up to 10 ,20uC within a few hours) and seasonal changes (from 0 to 35 ,40uC) ...responses to thermal stress ...resistant to subsequent thermal stress ... See full document

... ferences in correlation. Increasing as the number of genes on each microarray chip did not affect sensitivity or specificity (Additional file 1, Figure S6), supporting our decision to use simulations ... See full document

... converted to cDNA, labeled and hybridized to a Toray microarray for genome-wide transcript ...able to activate the RNA-induced silencing complex ...more gene expression changes than knockdown ... See full document

... used to obtain three different biological replicates of DNA samples from each of the two treatment ...subjected to a series of three 20 pulse sonications at 20% ...resuspended in 350 ul TE and ... See full document