[PDF] Top 20 Homeostasis of the T cell memory compartment
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Homeostasis of the T cell memory compartment
... In the adult mouse, the number of peripheral T cells is maintained within narrow ranges and is largely independent of the numbers of precursor and thymus cells ...study ... See full document
143
homeostasis of the IL-2-producing CD4 T cells and theirrole in the control of T regulatory cells function and number.
... refill the empty space in an attempt to reestablish the normal peripheral ...phenomenon of T cell proliferation in a lymphopenic environment without intentional immunization is known as ... See full document
174
Altered T cell memory and effector cell development in chronic lymphatic filarial infection that is independent of persistent parasite antigen.
... Finally, the altered cellular phenotypes seen in adult patients with long-term filarial infection, either past or present, was not seen in young filarial-infected children, despite their lack of T ... See full document
12
Regulatory T-cell development in the human thymus
... <1% of the patients, but in the majority of them the prevailing thymic hypo- plasia is associated with mild to moderate T-cell lymphopenia, and increased incidence ... See full document
7
A novel regulatory T cell population in the gut.
... individual T cell expresses just one of myriad different versions of the TCR, each of which responds to a particular ...allows the recognition of a large repertoire ... See full document
2
Human Infant Memory B Cell and CD4+ T Cell Responses to HibMenCY-TT Glyco-Conjugate Vaccine.
... Carrier-specific T cell and polysaccharide-specific B cell memory responses are not well characterised in infants following glyco-conjugate ...if the number of Meningococcal ... See full document
18
Decreased memory B cells and increased CD8 memory T cells in blood of breastfed children: the generation R study.
... CD8 T cells, the central memory subset was most significantly increased in breastfed ...be the result of stimulation of mature T ...binding of the bacterial ... See full document
16
Activated iNKT cells promote memory CD8+ T cell differentiation during viral infection.
... from the interface of the gradient, and washed once in 1% ...nylon cell strainer (Falcon, Franklin lakes, ...and cell suspensions were layered on a two-step discontinuous Percoll ... See full document
6
Human herpesvirus-8 infection leads to expansion of the preimmune/natural effector B cell compartment.
... explain the effects of HHV-8 on B ...perturb the homeostasis of B lymphocytes through anti-apoptotic viral proteins, cytokines or other soluble mediators able to affect the ... See full document
10
CD8 T cell memory to a viral pathogen requires trans cosignaling between HVEM and BTLA.
... trans-activation of HVEM by all its Ig- related ligands [43]. Naı¨ve T cells coexpress HVEM and BTLA on the cell surface at approximately 1:1 ratio, with only the ecto domain of ... See full document
14
T. gondii the ER is distributed throughout the cell
... to the extreme apical pole of the parasite ...portion the matrix of the organelle shows a spongeous appear- ance while the neck region is uniformly electron dense making ... See full document
21
Telomere biology of cutaneous T-Cell lymphomas
... cocktail of restriction enzymes, resulting in short genomic fragments and longer uncut ...probe. The average telomere length is determined by quantification of the intensity of labeled ... See full document
146
Altered Memory Circulating T Follicular Helper-B Cell Interaction in Early Acute HIV Infection.
... initiation of ART for maintaining low viremia and preserving immunity is a key objective of the RV254 ...one of the characteristic effects of increased viremia on the B ... See full document
17
The PICALM protein plays a key role in iron homeostasis and cell proliferation.
... portion of exon 13 [DPFSATV] was subcloned into the GFPN1 vector (Stratagene, La Jolla, CA, USA), downstream of the GFP ...into the bicistronic MSCV-IRES-eGFP (MIE) retroviral vector ... See full document
14
Naive and stem cell memory T cell subset recovery reveals opposing reconstitution patterns in CD4 and CD8 T cells in chronic graft vs. Host disease
... Despite the recent advances with patient-tailored therapies, allogeneic hematopoietic stem cell transplantation (allo-HSCT) has been increasingly used in the USA and in Europe for the ... See full document
15
Characterization of CD8+ T-CELL populations of the human peripheral blood
... + T-cell compartment encloses several subpopulations with multiple functionalities, including naïve, effector and memory ...subsets. The prevailing data describing these subsets in ... See full document
210
T cell Maturation and Regulatory T Cell Differentiation: From the Thymus to the Periphery
... regulatory T cells (Treg) are in control of pathological immune self reactivity and limit the immune response during infection ...in the thymus from developing thymocytes (nTreg) or in ... See full document
226
Obesity impairs γδ T cell homeostasis and antiviral function in humans.
... Vγ9Vδ2 T cell numbers, reduced IL-2Ra (CD25) expression, sensi- tivity to apoptosis, and accelerated terminal differentiation suggest that γδ T cells are lacking signals required for homeostatic ... See full document
16
CD4+ T cell homeostasis : the thymus, the cells and the environment
... that the size of the total peripheral T cell pool is regulated largely independently of thymus ...At the periphery, several compensatory mechanisms operate to bypass ... See full document
172
The role of IL-7 in the homeostasis of human naive and memory CD4+T cell subsets
... is the phosphoinositide 3-kinase (PI3K) signalling pathway which plays a key role in regulating cell survival, growth, metabolism and proliferation 89 .... The major substrate of PI3K is Akt, ... See full document
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