[PDF] Top 20 Immunoglobulin, somatic hypermutation and the survival of B cells
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Immunoglobulin, somatic hypermutation and the survival of B cells
... memory B cells, long-lived plasma cells constitute the survivors of primary ...Plasma cells are terminally differentiated B cells that lost Ig surface expression ... See full document
150
B cells at the crossroad of immune responses : insights from primary B-cell immunodeficiencies
... T1 and T2 transitional ...to the expression of phenotypic markers, such as CD21 and IgD, with T1 cells being IgM bright CD21 - IgD - and T2 cells defined IgM bright CD21 ... See full document
216
AF10 plays a key role in the survival of uncommitted hematopoietic cells.
... analyses of MLL- and CALM-AF10 rearrangements show differences in the location of AF10 breakpoints, but the OM-LZ domain is present in both fusion proteins (Figure S1) ...that ... See full document
8
The effect of the dibenzylbutyrolactolic lignan (-)-cubebin on doxorubicin mutagenicity and recombinogenicity in wing somatic cells of Drosophila melanogaster
... Brazil) and 5 ml of a solution containing ( )-cubebin alone (at a final concentration of ...Tween-80 and 3% ethanol in distilled water) and positive (DXR ...experiments. The ... See full document
7
Clastogenic activity of 2-chlorodeoxyadenosine in mammalian somatic cells
... in the treatment of lymphoproliferative disorders (Pott-Hoeck and Hiddemann, ...drug of choice in the treatment of hairy cell leu- kemia, but it is also highly efficient in other ... See full document
6
Biochemical and functional analysis of the T cell growth and survival bioactivities of human red blood cells.
... nucleated cells release membrane-derived vesicles (also called exosomes) resulting from the fusion of multivesicular endosomes with the plasma ...in the modulation of the ... See full document
119
Interferon-γ inhibits group B Streptococcus survival within human endothelial cells
... inside the phagocytic vacuoles. The reaction product, which suggests enzyme activity, was observed at higher levels in the HUVECs treated with IFN-γ than in the control cells ...Through ... See full document
4
Survival of Staphylococcus epidermidis biofilm-released cells in human blood and plasma
... SdrG and Aap bind to the cell surface through sortase-catalysed covalent interactions and contain a LPXTG motif linked to the ...peptidoglycan. The SdrG belongs to the Sdr ... See full document
66
The role of B cells in the early phase of rheumatoid arthritis
... cohort of RA patients with established disease and under B cell depletion therapy with RTX was also ...Considering the important role that BAFF has in B cell maturation and ... See full document
7
Collagen Promotes Higher Adhesion, Survival and Proliferation of Mesenchymal Stem Cells.
... counting of MSC grown on different matrices. (B) Cell proliferation on different matrices were analysed by MTT ...in cells grown on COL compared to CON, FBN and PLL ...FBN and PLL ... See full document
15
Estrogens regulate the survival and death communication between Sertoli and germ cells: a clue for male infertility?
... In the last decades estrogens have been regarded as “male hormones” playing an important role controlling male reproductive ...However, the effect of estrogens regulating testicular function ... See full document
61
CD137 is induced by the CD40 signal on chronic lymphocytic leukemia B cells and transduces the survival signal via NF-κB activation.
... on B cells derived from patients with various B-cell ...HeLa cells or cells expressing CD154 for 24 h, as indicated, and subjected to flow cytometric analysis for expression ... See full document
8
Extracellular Vesicles from Vascular Endothelial Cells Promote Survival, Proliferation and Motility of Oligodendrocyte Precursor Cells.
... OPC survival, proliferation and ...media of various types of endothelial cells (ECs) or Rat-1 fibroblastic cells, suspended in fresh serum-free medium and added to OPC ... See full document
14
Melanophore migration and survival during zebrafish adult pigment stripe development require the immunoglobulin superfamily adhesion molecule Igsf11.
... [59] and such interactions could occur in vivo during adult pigment pattern ...transplantation and genetic rescue experiments, and that igsf11 transcripts and protein are not detected in ... See full document
14
Variable contexts and levels of hypermutation in HIV-1 proviral genomes recovered from primary peripheral blood mononuclear cells
... mechanism of evasion (Braaten and Luban, 2001; Connor et al., 1997). One of these mechanisms of host restriction to HIV infection is mediated by the members of the ... See full document
11
The ultrastructure of the kinetochore and kinetochore fiber in Drosophila somatic cells
... Characterization of the structural domains of the Drosophila kinetochore at the light microscope ...S2 cells stably expressing CID-GFP (green) were immunostained for ... See full document
32
miR290-5p/292-5p activate the immunoglobulin kappa locus in B cell development.
... that the addition of STI571 to AMuLV-transformed pro-B cells induces expression of genes characteristic of the pre-B cell stage in development ...at the ... See full document
10
Protein phosphatase magnesium dependent 1A (PPM1A) plays a role in the differentiation and survival processes of nerve cells.
... PC6-3 cells differentiate into neuronal like ...process the cells proliferate rapidly for approximately 3 days, and then, concomitantly with the appearance of neuronal-like ... See full document
11
A role for PCNA ubiquitination in immunoglobulin hypermutation.
... for the Ig hypermutation pathway. Because of its high ratio of targeted DNA integration [16], the chicken DT40 cell line has become a popular genetic system to study DNA repair [17] ... See full document
10
Dorsomorphin promotes survival and germline competence of zebrafish spermatogonial stem cells in culture.
... eliminate the somatic cells and select for the piwil1:neo expressing ...Addition of dorsomorphin, a Bmp type I receptor inhibitor, prolonged spermatogonial stem cell (SSC) ... See full document
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