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The importance of apoptosis for immune regulation in Chagas disease

The importance of apoptosis for immune regulation in Chagas disease

... for the modulation of immune responses during ...infection, apoptosis can be induced through at least three distinct pathways: (i) ex- trinsic soluble or membrane attached ligands for death ... See full document

4

The Epidemiologic Importance of Triatoma brasiliensis as a Chagas Disease Vector in Brazil: a Revision of Domiciliary Captures during 1993-1999

The Epidemiologic Importance of Triatoma brasiliensis as a Chagas Disease Vector in Brazil: a Revision of Domiciliary Captures during 1993-1999

... concern the whole geographic range of this species, during the period of ...(MA) in the Northeast region (capital - ...north of Minas Gerais (MG) in the ... See full document

7

Cellular and genetic mechanisms involved in the generation of protective and pathogenic immune responses in human Chagas disease

Cellular and genetic mechanisms involved in the generation of protective and pathogenic immune responses in human Chagas disease

... expression of HLA-DR and lower expression of CD28, similar to what was described in indeterminate patients (Dutra et ...at the functional level distinguish these ac- tivated cell populations ... See full document

11

Different Infective Forms Trigger Distinct Immune Response in Experimental Chagas Disease

Different Infective Forms Trigger Distinct Immune Response in Experimental Chagas Disease

... infection in mice leads to strong activation of innate and adaptive immune response and ...example of a systemic infectious process. Based on this, in the present study we have ... See full document

10

Dendritic cells : a double-edged sword in immune responses during chagas disease

Dendritic cells : a double-edged sword in immune responses during chagas disease

... at the infection site (Haniffa et ...adaptive immune responses by capturing, processing and expressing antigens in the cell surface membrane (Planelles et ...range of innate receptors ... See full document

12

A Role for Extracellular Amastigotes in the Immunopathology of Chagas Disease

A Role for Extracellular Amastigotes in the Immunopathology of Chagas Disease

... role of abortive cycles of amastigote replication in the immunopathology of Chagas ...disease. The model predicts that the blockade of macrophage ... See full document

13

Apoptosis in parasites and parasite-induced apoptosis in the host immune system: a new approach to parasitic diseases

Apoptosis in parasites and parasite-induced apoptosis in the host immune system: a new approach to parasitic diseases

... that regulation of host cell apoptosis is a critical determinant factor in host-patho- gen ...cell apoptosis in different ways, either to increase their life span within ... See full document

7

Chagas' disease: an update on immune mechanisms and therapeutic strategies

Chagas' disease: an update on immune mechanisms and therapeutic strategies

... role in T. cruzi infection by killing infected cells through the production of perforin and granzyme B or through the Fas/Fas ligand ...with the Brazil strain of T. cruzi did not ... See full document

12

Perspectives of vaccination in Chagas disease revisited

Perspectives of vaccination in Chagas disease revisited

... - In 1982, we stressed that the mouse model obviously was not an adequate experi- mental model for Chagas ...for Chagas disease. The mouse is a handy and useful experimental ... See full document

6

Regulation of the apoptosis pathway in Rhipicephalus annulatus ticks by the protozoan Babesia bigemina

Regulation of the apoptosis pathway in Rhipicephalus annulatus ticks by the protozoan Babesia bigemina

... ectoparasites of a huge variety of terrestrial vertebrates comprising reptiles, birds, amphibians and mammals (including humans) (Anderson and Magnarelli, 2008; Hajdušek et ...ago in the ... See full document

61

Immunopathology of Chagas Disease

Immunopathology of Chagas Disease

... forms of Chagas disease (acute, indeterminate and chronic cardiac) present strong evidences for the participation of the immune system on ...infection, the intense ... See full document

10

The relative importance of innate immune priming in Wolbachia-mediated dengue interference.

The relative importance of innate immune priming in Wolbachia-mediated dengue interference.

... and the somatic infection of ...increase in expression of opsonisation genes [11]. Evidence for the role of opsonisation in protection against Plasmodium in this ... See full document

10

The  importance of apoptosis of Plasmodium-infected cells in the generation of immunity against malaria infection

The importance of apoptosis of Plasmodium-infected cells in the generation of immunity against malaria infection

... to the InfC57BL/6 group (7 versus 3 days). Although the reasons behind this miss-immunization are unclear, one can speculate that it might have been due to an improper administration of the ... See full document

52

Surveillance of Chagas disease vectors in municipalities of the state of Ceará, Brazil

Surveillance of Chagas disease vectors in municipalities of the state of Ceará, Brazil

... found in wild ...otopes in peridomicile and are sometimes infected with ...2008). The authors of the last paper suggest the need for epidemiological surveillance in ... See full document

7

Leptin levels in different forms of Chagas’ disease

Leptin levels in different forms of Chagas’ disease

... product of the ob gene, which is produced primarily by ...with the central regulation of satiety and energy metabolism, increasing evidence now indicates that leptin may be an important ... See full document

6

Evasion of immune responses by Trypanosoma cruzi, the etiological agent of Chagas disease

Evasion of immune responses by Trypanosoma cruzi, the etiological agent of Chagas disease

... replication of T. cruzi depends on production of TGF-β by macrophages engulfing dead cells ...Injection of apoptotic cells increases parasitemia in vivo, and treatment with the ... See full document

8

The pathogenesis of Chagas' disease: when autoimmune and parasite-specific immune responses meet

The pathogenesis of Chagas' disease: when autoimmune and parasite-specific immune responses meet

... Chagasdisease is a major health problem in Latin America, where it constitutes one of the leading causes of heart ...fourth of Trypanosoma cruzi-infected individuals ... See full document

13

Different infective forms trigger distinct immune response in experimental Chagas disease.

Different infective forms trigger distinct immune response in experimental Chagas disease.

... functional in relation to parasite-host interaction and/or target cell invasion, they differ in the molecules present on the ...to the variability that the forms of ...on ... See full document

10

ORAL TRANSMISSION OF CHAGAS DISEASE: IMPORTANCE OF Trypanosoma cruzi BIODEME IN THE INTRAGASTRIC EXPERIMENTAL INFECTION

ORAL TRANSMISSION OF CHAGAS DISEASE: IMPORTANCE OF Trypanosoma cruzi BIODEME IN THE INTRAGASTRIC EXPERIMENTAL INFECTION

... role of the strain of the parasite. Results of the present study have indicated a clear difference in infectivity of two different strains of ...by ... See full document

7

The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington's Disease.

The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington's Disease.

... Enrichment of other regulatory signals with H3K4me3 peaks In addition to TF binding data from the ENCODE consortium, we also compared our H3K4me3 peaks with the regulatory signals from ... See full document

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