[PDF] Top 20 Insulin Substrate Receptor (IRS) proteins in normal and malignant hematopoiesis
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Insulin Substrate Receptor (IRS) proteins in normal and malignant hematopoiesis
... erythropoietin receptor; ERa, estro- gen receptor a; ERb, estrogen receptor b; ERK, extracel- lular signal-regulated kinase; FYN, FYN proto-oncogene, Src family tyrosine kinase; GAB2, ... See full document
11
Modulation of Insulin Receptor Substrate-1 and Some Inflammatory Variables in Hyperinsulinemic Rats Treated with Cinnamon Extract
... ingested and to have many pharmacological ...cardiac Insulin Receptor Substrate-1 (IRS-1) and their relations to some inflammatory variables in hyperinsulinemic ...studied ... See full document
8
Beneficial effects of Ginkgo biloba extract on insulin signaling cascade, dyslipidemia, and body adiposity of diet-induced obese rats
... the insulin signaling cascade, especially in obese ...on insulin tolerance, food intake, body adiposity, lipid profile, fasting insulin, and muscle levels of insulin ... See full document
9
Secreção da insulina: efeito autócrino da insulina e modulação por ácidos graxos.
... role in the regulation of glucose homeostasis and acts in a coordinated fashion on cellular events that regulate the meta- bolic and growth ...The insulin receptor β-subunit, ... See full document
9
The insulin receptor substrate 1 associates with phosphotyrosine phosphatase SHPTP2 in liver and muscle of rats
... its receptor resulting in the phosphorylation of its cytosolic substrate, insulin receptor substrate-1 (IRS-1) which, in turn, associates with proteins containing ... See full document
6
Formal modeling and analysis of ER-α associated Biological Regulatory Network in breast cancer
... kinase and Serine/Threonine-Protein Kinases (PI3K-AKT) pathway which is involved in multiple mammalian cellular processes of growth and development (Ewing & Goff, ...pathway in BC (Bailey ... See full document
33
Tissue-specific regulation of IRS-1 in unilaterally nephrectomized rats
... its receptor, resulting in the phosphorylation of its cytosolic substrate, insulin receptor substrate 1 ...a substrate for different peptides and growth factors, ... See full document
5
Insulin‑like growth factor and growth hormone receptor in postpartum lactating beef cows
... the insulin-like growth factors (IGF-I and II), the IGF and insulin receptors, and IGF-binding proteins-1-6 and the localization of their gene products in ... See full document
7
Aflatoxin B1 up-regulates insulin receptor substrate 2 and stimulates hepatoma cell migration.
... or insulin in the serum correlated with increased risk of cancer development ...up-regulated in a variety of human ...migration and invasion. IRS1 and IRS2 are cytoplasmic adaptor ... See full document
11
Knockdown of insulin receptor substrate 1 reduces proliferation and downregulates Akt/mTOR and MAPK pathways in K562 cells
... knockdown in K562 cells, we checked the activation status of Akt and P70S6K, essential proteins of the Akt/mTOR pathway, and ERK1/2, one of the MAPK ...survival, and death [29,30]. IRS1 ... See full document
8
Discovery of a novel target for the dysglycemic chromogranin A fragment pancreastatin: interaction with the chaperone GRP78 to influence metabolism.
... novel proteins that interact with PST, we used affinity chromatography with biotinylated human PST-amide and a murine liver homogenate, eluting the bound protein by lowering pH from ...digestion and ... See full document
12
Protein disulfide-isomerase interacts with a substrate protein at all stages along its folding pathway.
... peptides and unfolded proteins [26,33–35], but no study has been done with a partly-folded intermediate on an oxidative protein folding ...expressed and purified [26] and its interaction with ... See full document
11
Identification of distinctive patterns of USP19-mediated growth regulation in normal and malignant cells.
... patterns in human breast cells, normal vs carcinoma, and prostate cancer cell lines as well as rat fibroblasts raised the question of whether the cell growth response to USP19 depletion may somehow ... See full document
9
Triacylglycerols and body fat mass are possible independent predictors of C3 in apparently healthy young Brazilian adults
... effect) and the release of cytokines and other proin- flammatory ...leptin and adiponectin, which are secreted by adipocytes, adipokines may also affect inflam- mation and ...process and ... See full document
7
Characterization of bone pathologies in the ins2+/akita mouse, a new model for diabetes insulindependent: contribution for a better understanding of the disease in humans
... (BS/TV) and trabecular number (Tb.N) in Ins2 +/akita are always significantly increased at all time points, and expression of genes associated with bone formation (Oc and Runx2) showed to be ... See full document
125
Braz. J. Pharm. Sci. vol.50 número4
... leptin in experimental models (Fujikawa et ...WAT and binds to its receptor (LEPR) in GABAergic neurons, that secrete gamma-aminobutyric acid (GABA) as well as pro-opiomelanocortin neurons ... See full document
16
Angiotensin II Inhibits Insulin Binding to Endothelial Cells
... In this study, we tried to investigate whether ATII afects in- sulin binding on endothelial ...that in- sulin binding on the endothelium is an initial step in eNOS ac- tivation via ... See full document
5
Review: Structural requirements for signalling and regulation of AT1-receptors
... Süpeki and Judit Bakacsiné Rácz is greatly appre- ...utilised in this study was kindly provid- ed by Dr Stephen A Wank (NIDDK, NIH, Bethesda, Maryland, ...(051804/Z/97/Z), and by grants from the ... See full document
8
Long live FOXO: unraveling the role of FOXO proteins in aging and longevity
... hermaphrodite and a ...pathway in aging was first discovered in ...Mutations in DAF-2 (dauer larvae formation-2), a hormone receptor similar to insulin and IGF-1 ... See full document
12
Selective release of microRNA species from normal and malignant mammary epithelial cells.
... Transcript and Release Rate of ...evaluated in Figure 1 are plotted according to chromosomal location (chromosomes 1-X) from top to ...indicated in color. Note that for cluster miR-200c-141, which is ... See full document
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