[PDF] Top 20 Molecular Markers of Epithelial to Mesenchymal Transition in Prostate Cancer
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Molecular Markers of Epithelial to Mesenchymal Transition in Prostate Cancer
... Prostate cancer is the second most frequently diagnosed cancer and the sixth leading cause of cancer death among males worldwide, representing the most common form of ... See full document
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Role of Bmi-1 in regulation of ionizing irradiation-induced epithelial-mesenchymal transition and migration of breast cancer cells.
... shown to be an upstream regulator of the PI3K/Akt pathway [13,18,19], which plays a critical role in regulation of the EMT process and cell ...correlated to reduced phosphorylation ... See full document
10
Panepoxydone targets NF-kB and FOXM1 to inhibit proliferation, induce apoptosis and reverse epithelial to mesenchymal transition in breast cancer.
... breast cancer have been classified into four main subtypes - luminal A, luminal B, Her-2+ enriched and ...used to direct the use of targeted therapies such as endocrine-based therapy for hormone ... See full document
12
A novel network profiling analysis reveals system changes in epithelial-mesenchymal transition.
... analysis of molecular networks is a promising strategy for making individual risk predictions and treatment decisions in cancer ...network of a cell to be reconstructed from ... See full document
17
A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition.
... promotes epithelial-like properties in breast cancer cells Next, we investigated the role of miR-203 in relationship with SNAI1 expression in breast carcinoma ...cells. In ... See full document
7
Investigating the link between molecular subtypes of glioblastoma, epithelial-mesenchymal transition, and CD133 cell surface protein.
... due to chance whenever the results are ...demonstrated in Table 4, signatures of CD133 obtained from normal samples have a stronger negative correlation with the signatures of ...signatures ... See full document
14
Prostate Cancer Exosomes As Molecular Predictors Of Response To Therapy
... response to therapy. This would allow for a better stratification of the patients to receive the most efficacious, therapeutic ...treatment. Cancer cell derived exosomes, with their ... See full document
57
Ginsenoside 20(S)-Rg3 targets HIF-1α to block hypoxia-induced epithelial-mesenchymal transition in ovarian cancer cells.
... exist to the eventual translation of 20(S)-Rg3 to clinical ...One of them entails the lack of knowledge still about the molecular target(s) 20(S)-Rg3 directly interacts with ... See full document
12
A CD44high/EGFRlow subpopulation within head and neck cancer cell lines shows an epithelial-mesenchymal transition phenotype and resistance to treatment.
... Mortality in head and neck squamous cell carcinoma (HNSCC) is high due to emergence of therapy resistance which results in local and regional recurrences that may have their origin in ... See full document
10
The role of the miR-200 family in the epithelial-to-mesenchymal transition (EMT)
... binding to partially complementary sequences in target mRNAs to induce mRNA decay, translational repression or both 1 ...bind to hundreds of mRNAs, sometimes having a strong effect but ... See full document
177
Afadin downregulation by helicobacter pylori Induces epithelial to mesenchymal transition in gastric cells
... protein of the adherens junctions, which regulates the formation and stabilization of both the adherens and the tight ...expression of Afadin has been shown in cancer and its loss has ... See full document
13
Upregulation of TrkB promotes epithelial-mesenchymal transition and anoikis resistance in endometrial carcinoma.
... expression of TrkB in solid cancers [6–8], this is the first study to address the function of TrkB in human ...expressed in human endometrium, and its expression may be greater ... See full document
17
Prolyl-4-hydroxylase 3 (PHD3) expression is downregulated during epithelial-to-mesenchymal transition.
... their mesenchymal-like morphology back to a more epithelial phenotype, we created a stable PHD3-Wt-overexpress- ing MiaPaca2 cell ...able to achieve high levels of PHD3 protein ... See full document
11
S100 calcium-binding protein A6 promotes epithelial-mesenchymal transition through β-catenin in pancreatic cancer cell line.
... homeostasis in adults[9]. Aberrant regulation of this pathway is therefore associated with a variety of diseases, including cancer, fibrosis and neuro- ...composed of the wnt ligand ... See full document
14
1-Methyl-D-tryptophan potentiates TGF-β-induced epithelial-mesenchymal transition in T24 human bladder cancer cells.
... hallmarks of several types of cancer including bladder ...One of the mechanisms involved in these processes has been linked to indoleamine 2,3-dioxygenase ...effects in ... See full document
16
Inhibition of SK4 Potassium Channels Suppresses Cell Proliferation, Migration and the Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer Cells.
... breast cancer (TNBC) are limited; intermediate-conductance calcium-activated potassium (SK4) channels are closely involved in tumor progression, but little is known about these channels in ...aimed ... See full document
17
Liver cancer-derived hepatitis C virus core proteins shift TGF-beta responses from tumor suppression to epithelial-mesenchymal transition.
... targets in function of its level of ...needed to evoke a biological effect. In addition to Smad pathways, non-smad-dependent signal transduction downstream of TGF-b ... See full document
13
Chronic respiratory aeroallergen exposure in mice induces epithelial-mesenchymal transition in the large airways.
... decrease of protein expression of the tight junction components CAR and occludin, although no change was seen in the mRNA levels of these epithelial ...regulation of tight ... See full document
9
Critical roles of p53 in epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma cells.
... [45]. In addition, wild type p53 upregulates MDM2 and forms a p53-MDM2-Slug complex to degrade Slug in non-small-cell lung cancer cells, and Slug expression level correlates positively with ... See full document
12
Col1A1 production and apoptotic resistance in TGF-β1-induced epithelial-to-mesenchymal transition-like phenotype of 603B cells.
... resistant to TNF-a/SC-514-induced ...effects of TGF- b1 on 603B cells, suggesting that TGF-b1-induced EMT-like alterations might contribute to cholangiocyte accumulation during liver fibrosis via ... See full document
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