[PDF] Top 20 Nanoencapsulation of new compounds with potentioal anti-leishmanial activity
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Nanoencapsulation of new compounds with potentioal anti-leishmanial activity
... use of SLN: the low encapsulation efficiency, resulting from the transformation of polymorphic lipid matrix, which can cause the expulsion of drug molecules from the SLN matrix [9], and; physical ... See full document
126
A Convenient Synthesis, Reactions and Biological Activity of Some New 6H-Pyrazolo[4’,3’:4,5]thieno[3,2-d][1,2,3]triazine Compounds as Antibacterial, Anti-Fungal and Anti-Inflammatory Agents
... series of novel pyrazolothienotriazines ...result of resistance of some bacterial and fungi strains to the existing antimicrobial therapy, we got interested in the search for syntheses of more ... See full document
14
Action of new porphyrin conjugates with potential anti-malaria activity on membranes
... range of compounds, with low molecular weight and ...emerged new ionization techniques that allow the analysis of bigger molecules, nonvolatile and also mixtures ...variety of ... See full document
97
Anti-tumoral activity of imidazoquines, a new class of antimalarials derived from primaquine
... inhibitory activity of imidazoquines, antimalarial imidazolidin-4-ones derived from prima- quine, on human cancer cell lines HT-29, Caco-2, and MCF-7 has been ...some of its derivatives were ... See full document
5
Anti-Trichophyton Activity of Protocatechuates and Their Synergism with Fluconazole
... 20–25% of the world’s ...conjunction with the limited spectrum of action of such drugs, emphasises the need to develop new antifungal ...spectrum of biological ...antifungal ... See full document
10
Screening and isolation of compounds with antimicrobial activity produced by multi-resistant bacteria
... for new active molecules in natural products, not only antibiotics but also other molecules with possible medicinal ...% of the drug substances available in the pharmaceutical industry were natural ... See full document
50
A Review on Medicinal Plants with Anti-Ulcer Activity
... treatment of peptic ulcer. This report reviews the anti-acid/anti-peptic, gastro- protective and/or anti-ulcer properties of the most commonly employed herbal medicines and their ... See full document
6
Investigation into in vitro anti-leishmanial combinations of calcium channel blockers and current anti-leishmanial drugs
... because of resistance to antimoni- als, the toxicity of current treatments and the length of the course of ...shown anti-leishmanial activity; therefore their use in ... See full document
7
Identification of Trypanocidal Activity for Known Clinical Compounds Using a New Trypanosoma cruzi Hit-Discovery Screening Cascade.
... terms of toxicity and efficacy. There is thus an urgent need to develop new treatments either via a repurposing strategy or through the development of new chemical ...identification of ... See full document
19
Design and synthesis of new benzophenone derivatives with in vivo anti-inflammatory activity through dual inhibition of edema and neutrophil recruitment.
... distribution of benzophenones in the score scatter plot based on the biologically relevant descriptors resulted in two clusters: one closer to ketoprofen, suggesting similar molecular features, and the other ... See full document
23
Anti-leishmanial and structure-activity relationship of ring substituted 3-phenyl-1-(1,4-di-N-oxide quinoxalin-2-yl)-2-propen-1-one derivatives
... Trypanosomatidae of the Leishmania genus extended over Africa, Asia, Europe, North and South America, with an estimated 12 million people infected ...forms of leishmaniasis (Davis et ...types ... See full document
3
Anti-leishmanial activity of alkaloidal extract from Aspidosperma ramiflorum
... lack of an effective anti-leishmanial drug led a renewed interest in the study of traditional remedies as sources for the development of new chemotherapeutic compounds ... See full document
3
Bioactive compounds from seaweed with in vitro anti-leukemia activity
... amount of research spanning this field, the statistics on cancer are not ...type of cancer with a worldwide incidence of ...rate of 3.4% (out of all ...20% of all ... See full document
111
Development of proliposomes as a vehicle to deliver new molecules with antitumor activity
... progression of the reaction, using the intermediate 4 and a standard previously obtained as ...washed with cold carbon ...solid of 1-(dibromomethyl)-3,4-dimethoxy-9H-xanthen-9- one (5, ... See full document
134
Screening of biological activity of a panel of putative anticancer compounds
... induction of apoptosis, by means of interactions with cyclins and cyclin-dependent kinases [95, ...these compounds can take action on the cell cycle arrest of human cancer cell lines in ... See full document
81
Synthesis of new glycosylated flavonoids with inhibitory activity on cell growth
... activities, with the glycoside moiety playing an important role in the mechanism of action of these ...inhibitory activity on cell growth of these classes of compounds, ... See full document
10
Nanoencapsulation of luminescent 3-hydroxypicolinate lanthanide complexes
... Because of the high sensitivity of the morphology of these nanostructures to the synthetic conditions employed, the particle size of the nanoparticles could vary ...diameter of the ... See full document
7
Antimicrobial activity of calcium hydroxide associated with a new vehicle (Triethanolamine)
... teeth with previous endodontic treatment and apical periodontitis without ...selection of these ...associated with persistent infections and resistant to different atmospheric conditions ... See full document
5
In vitro evaluation of the anti-leishmanial activity and toxicity of PK11195
... the anti-leish- manial effect of the TSPO ligand PK11195 on intracellu- lar ...infected with stationary-phase promastigotes of ...ratio of 10:1 for 6 h. The cells were then washed ... See full document
9
Interaction of vanadium compounds with DNA
... coordination compounds as therapeutics for different medical applications are currently one of the most demanding subjects in the biochemical ...lowering of glucose level in urine of two out ... See full document
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