[PDF] Top 20 A novel live-attenuated vaccine candidate for mayaro Fever.
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A novel live-attenuated vaccine candidate for mayaro Fever.
... IRES-based attenuated alphaviruses are also incapable of replication after intrathoracic inoculation into ...highly attenuated, only producing minimal signs of disease in the highly stringent A129 model ... See full document
9
Development of a novel, single-cycle replicable rift valley Fever vaccine.
... Valley fever virus (RVFV) (genus Phlebovirus, family Bunyaviridae) is an arbovirus that causes severe disease in humans and livestock in sub-Saharan African ...a live attenuated vaccine ... See full document
13
Evaluation of the 1329L as a candidate to delete for production of a viral attenuated vaccine against ASFV
... This novel strategy to modify and/or manipulate gene expression in mouse models using virus host evasion genes constitutes the basis of the construction of an I329L macrophage restricted expression mouse, an ... See full document
100
Rev. Soc. Bras. Med. Trop. vol.40 número2
... are: Mayaro (MAYV), Venezuelan equine encephalitis (VEEV), Eastern equine encephalitis (EEEV) and Chikungunya (CHIKV), which are 70-nm enveloped viruses that have an icosahedral capsid and single-stranded ... See full document
6
Influenza H5 hemagglutinin DNA primes the antibody response elicited by the live attenuated influenza A/Vietnam/1203/2004 vaccine in ferrets.
... a vaccine that is broadly cross-reactive to diverse ...ca vaccine were protected from various lethal doses of heterologous H5N1 wt viruses even in the absence of detectable Nt Ab in the serum, through a yet ... See full document
9
Rev. Soc. Bras. Med. Trop. vol.49 número1
... dengue fever occurred in several cities where the games were played, tourists could also have acquired the viruses, possibly carrying them when going back to their respective ... See full document
7
Development of a VLP-based HCV vaccine candidate
... The Hepatitis C Virus (HCV) infects approximately 3% of the world population, being one of the major causes of liver cirrhosis and hepatocellular carcinoma. The development of safe, effective and affordable prophylactic ... See full document
52
A glycoprotein E gene-deleted bovine herpesvirus 1 as a candidate vaccine strain
... A bovine herpesvirus 1 (BoHV-1) defective in glycoprotein E (gE) was constructed from a Brazilian genital BoHV-1 isolate, by replacing the full gE coding region with the green fluorescent protein (GFP) gene for selection. ... See full document
9
Downstream strategies for VLPs as candidate universal vaccine for Influenza
... Currently marketed influenza vaccines are only efficient against homolo- gous viruses, thus requiring a seasonal update based on circulating sub- types. This constant reformulation adds several challenges to manufac- ... See full document
306
High resolution human leukocyte antigen class I allele frequencies and HIV-1 infection associations in Chinese Han and Uyghur cohorts.
... In our Uyghur cohort, the frequency of HLA-B*5101 was significantly higher in the HIV-1 negative group. A novel HIV-1 vaccine candidate designed for B*5101 positive individuals protected mice against ... See full document
9
Comparative sequence analysis of the P-, M- and L-coding region of the measles virus CAM-70 live attenuated vaccine strain
... AIK-C vaccine was investigated ...AIK-C vaccine and Ed- monston wild type at amino acid position 278 of the F gene demonstrated that leucine was responsible for reduced fusion capabil- ity and that ... See full document
10
Toward a vaccine against Argentine hemorrhagic fever
... Cross-protection between Tacaribe com- plex viruses: presence of neutralizing an- tibodies against Junin virus (Argentine hemorrhagic fever) in guinea pigs infec- te[r] ... See full document
9
Protection of chickens against fowl typhoid using field vaccine programs formulated with the live attenuated strain Salmonella Gallinarum ΔcobSΔcbiA
... and fever. The use of a live attenuated strain of SG, with deletions on cpxR and lon genes, could also protect chickens against fowl typhoid, and only slight anorexia and depression were tem- ... See full document
5
Live Vaccine in Children with DiGeorge/22q11.2 Deletion Syndrome
... Material and Methods: Retrospective study with analysis of the clinical records of children with chromosome 22q11.2 deletion syn- drome and DiGeorge syndrome phenotype, followed in a Primary Immunodeficiency center. Data ... See full document
6
Evaluation of the Leptospira interrogans Outer Membrane Protein OmpL37 as a Vaccine Candidate.
... OmpL37 is a potential OMP from L. interrogans and fulfils several requirements for a potential vaccine candidate. It was recently characterized as a cell surface-exposed protein [12], that binds to several ... See full document
13
Developing an HIV vaccine: the role of efficacy studies in nonhuman primates.
... of candidate HIV/AIDS vaccines for these trials have to be defi ...HIV/AIDS vaccine remain unknown. The Global HIV/AIDS Vaccine Enterprise prioritizes research on vaccines eliciting neutralizing ... See full document
2
Delayed-type hypersensitivity in human volunteers immunized with a candidate leprosy vaccine
... We report here the results of a study carried out under the IMMLEP program that examines the DTH response among human volunteers in Norway who were immunized with thi[r] ... See full document
5
Novel strategies to enhance vaccine immunity against coccidioidomycosis.
... a novel adjuvant conjugated with the live Coccidioides ...of live arthroconidia from the vaccine strain [14] (Figure ...the vaccine to C5aR-bearing MW and DC, inducing phagocytosis and ... See full document
4
Iliano V Coutinho-Abreu, Marcelo Ramalho-Ortigao
... TBV vaccine with a recombinant protein plus adjuvant seems to be a reliable option for a phase 1 trial as this vaccination strategy induced strong reduction of ... See full document
12
Rev. Soc. Bras. Med. Trop. vol.48 suppl.1
... 23,000 cases caused by DENV1, as reported by the FMT-HVD (Figure 1). In 2001, DENV2 produced a second large outbreak of approximately 9,200 reported cases, including, for the fi rst time in Amazonas State, 67 cases of ... See full document
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