[PDF] Top 20 Opposing roles for interferon regulatory factor-3 (IRF-3) and type I interferon signaling during plague.
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Opposing roles for interferon regulatory factor-3 (IRF-3) and type I interferon signaling during plague.
... Wild type Y. pestis can survive and even replicate in macro- phages yet cause disease due to exponential growth of extracellular bacteria that secrete cytotoxins (Yops) and other virulence factors ... See full document
15
Type I interferon induction is detrimental during infection with the Whipple's disease bacterium, Tropheryma whipplei.
... Second and more strikingly, we found that a robust type I IFN response was induced by viable ...of type I IFN in host resistance to many types of viruses, only few papers report their ... See full document
13
Enhancing Interferon Regulatory Factor 7 Mediated Antiviral Responses and Decreasing Nuclear Factor Kappa B Expression Limit HIV-1 Replication in Cervical Tissues.
... MDM and human lymphoid tissue ...TLR3 and enhancing expression of Type I IFN and several IRFs particularly IRF7 ...day 3 after infection (Fig 2F), which was associated with no ... See full document
18
LPS regulates SOCS2 transcription in a type I interferon dependent autocrine-paracrine loop.
... cells and includes 11 members in humans and 13 in mouse ...domain and subsequent activation of cellular programs ...TLR signaling: (I) the MyD88-dependent pathway, which recruits the ... See full document
10
Papel do interferon do tipo I em neutrófilos durante a malária
... por interferon (ISGs) e da alta frequência de neutrófilos de baixa ...por interferon do tipo ...que interferon do tipo I tem um papel crucial na ativação de neutrófilos e consequentemente na ... See full document
96
Terapia gênica com interferon-alfa no controle do câncer colorretal
... Abstract: Interferon alpha (IFN-α) is a type I IFN with great therapeutic potential, since it is able to directly fight tumor cells and enhance the maturation of dendritic cells (DCs), the ... See full document
53
J. bras. pneumol. vol.43 número3
... um interferon-gamma release assay (IGRA, ensaio de liberação de interferon-gama) e os fatores relacionados com esses resultados em pessoas vivendo com HIV/AIDS ...células/mm 3 ) apresentaram maior ... See full document
4
Hepatitis C Virus Driven AXL Expression Suppresses the Hepatic Type I Interferon Response.
... AXL and SOCS3 are induced during HCV infection, we examined their expres- sion in Huh-7 cells containing a HCV subgenomic replicon (SGR), which expresses only non- structural viral proteins, and in ... See full document
16
Rev. Bras. Hematol. Hemoter. vol.32 número2
... of Interferon and STI571, foram randomizados 503 pacientes com LMC em fase crônica para o braço do interferon alfa e citarabina e 503 pacientes para o braço do imatinibe, permi- tindo que houvesse a ... See full document
1
Citocinas e proteínas de fase aguda do soro como marcadores de regressão da resposta inflamatória ao tratamento da tuberculose pulmonar
... de interferon-gama (IFN-γ), tumor necrosis factor-alpha (TNF-α, fator de necrose tumoral-alfa), interleucina-10 (IL-10) e transforming growth factor-beta (TGF-β, fator transformador de ... See full document
8
Arq. NeuroPsiquiatr. vol.70 número10
... with interferon beta (IFNb) and glatiramer acetate ...IFNb and GA have been ...IFNb-1b and GA among relapsing-remitting multiple sclerosis (RRMS) ...IFNb and GA in ninety-one RRMS ... See full document
6
Schmallenberg virus infection of adult type I interferon receptor knock-out mice.
... necropsy and the amount of SBV RNA in ...blood and spleen; this was also the animal that had displayed the least degree of weight ...days 3 and 8, mouse 10 was already recovering quickly ... See full document
5
Bridging the species divide: transgenic mice humanized for type-I interferon response.
... humanized type I interferon receptors (IFNARs) enabling the study of type I human interferons (Hu-IFN-Is) in ...IFNAR1 and IFNAR2 with the human extracellular domains being fused ... See full document
12
Reversible silencing of cytomegalovirus genomes by type I interferon governs virus latency.
... of type I interferon ...infected and that the infection becomes fully ...cells, and monitored the long-term IFNb effects for up to 19 dpi in growth-arrested LSECs (20,000 ...0.1 ... See full document
14
Interferon therapy shifts natural killer subsets among Egyptian patients with chronic hepatitis C
... history and clinical examination were carried out for all ...cant and persistent symptoms, b) fl uctuating or persistently elevated ALT and AST (> ...albumin and prothrombin time, c) ul- ... See full document
8
The battle between rotavirus and its host for control of the interferon signaling pathway.
... efficiently and cause disease, whereas heterologous strains ...mice and those lacking either type I or type II IFN receptors ...NSP1 and virion cell- attachment protein VP4 are ... See full document
8
Rev. bras. farmacogn. vol.25 número2
... fastigiatum and to evaluate the frequency of tumor necrosis factor alpha and interferon gamma producing cells in peripheral blood lymphocytes stimulated with phorbol myristate acetate in the ... See full document
5
A human torque teno virus encodes a microRNA that inhibits interferon signaling.
... analysis and, (2) As an initial test of the TTV as a potential small RNA ...preparations and assayed for miRNA expression by Northern blot analysis (Figure ...virus and Figure ...vectors and ... See full document
14
Critical role of constitutive type I interferon response in bronchial epithelial cell to influenza infection.
... apoptosis and limit viral replication, before it had any effect on cell ...replication, and inhibition of IFNAR2 markedly reduced IFN-b-induced apoptosis and increased viral ...of type ... See full document
14
Varicella Viruses Inhibit Interferon-Stimulated JAK-STAT Signaling through Multiple Mechanisms.
... JAK-STAT signaling we constructed a conditionally ORF63/ORF70-expressing mutant using a recombinant bacteri- al artificial chromosome containing the complete SVV genome (SVV BAC) ...ORF63 and ORF70 using ... See full document
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