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[PDF] Top 20 Role of Peroxisome Proliferator-Activated Receptor α in Diabetic Nephropathy

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Role of Peroxisome Proliferator-Activated Receptor α in Diabetic Nephropathy

Role of Peroxisome Proliferator-Activated Receptor α in Diabetic Nephropathy

... prolonged in PPARα-null mice compared to the wild-type controls, suggesting that PPARα afects the duration of the inlammatory response, possibly by limiting cytokine expression and also by inducing genes ... See full document

10

A Novel Cytosolic Isoform of Mitochondrial Trans-2-Enoyl-CoA Reductase Enhances Peroxisome Proliferator-Activated Receptor α Activity

A Novel Cytosolic Isoform of Mitochondrial Trans-2-Enoyl-CoA Reductase Enhances Peroxisome Proliferator-Activated Receptor α Activity

... involved in mitochondrial synthesis of fatty acids and is highly expressed in ...nuclear receptor binding factor-1, which was originally reported with yeast two-hybrid screening as a binding ... See full document

10

Modeling the role of peroxisome proliferator-activated receptor γ and microRNA-146 in mucosal immune responses to Clostridium difficile.

Modeling the role of peroxisome proliferator-activated receptor γ and microRNA-146 in mucosal immune responses to Clostridium difficile.

... sequences in the 39 untranslated regions, leading to suppression of translation and/or degradation of ...critical role in immunity and inflammation ...found in Crohn’s disease ... See full document

10

Assessment of chitosan-affected metabolic response by peroxisome proliferator-activated receptor bioluminescent imaging-guided transcriptomic analysis.

Assessment of chitosan-affected metabolic response by peroxisome proliferator-activated receptor bioluminescent imaging-guided transcriptomic analysis.

... used in food industry as a weight-loss aid and a cholesterol-lowering ...the in vivo targeting sites and mechanisms of chitosan remain to be ...clarified. In this study, we constructed ... See full document

10

Activation of peroxisome proliferator-activated receptor gamma by rosiglitazone increases sirt6 expression and ameliorates hepatic steatosis in rats.

Activation of peroxisome proliferator-activated receptor gamma by rosiglitazone increases sirt6 expression and ameliorates hepatic steatosis in rats.

... The in vivo experiments suggested that coordinated regulation of adiponectin, Sirt6, and AMPK may play a role in RGZ’s protective ...up-regulation of Sirt6 and its related genes as well ... See full document

11

Peroxisome proliferator-activated receptor-gamma agonists suppress tissue factor overexpression in rat balloon injury model with paclitaxel infusion.

Peroxisome proliferator-activated receptor-gamma agonists suppress tissue factor overexpression in rat balloon injury model with paclitaxel infusion.

... diversity of stimuli augmenting TF expression, three MAPKs, including JNK, p38, and ERK, are involved in the most of the stimulant-induced TF expression ...activities of transcription factors ... See full document

14

Peroxisome proliferator-activated receptor γ deficiency in T cells accelerates chronic rejection by influencing the differentiation of CD4+ T cells and alternatively activated macrophages.

Peroxisome proliferator-activated receptor γ deficiency in T cells accelerates chronic rejection by influencing the differentiation of CD4+ T cells and alternatively activated macrophages.

... component in the immune response involved in allograft rejection ...PPARc in T cells, PPARc agonists cannot exert protective function on ...macrophages. In additional studies, we investigated ... See full document

9

Lysophosphatidic acid activates peroxisome proliferator activated receptor-γ in CHO cells that over-express glycerol 3-phosphate acyltransferase-1.

Lysophosphatidic acid activates peroxisome proliferator activated receptor-γ in CHO cells that over-express glycerol 3-phosphate acyltransferase-1.

... for peroxisome proliferator activated receptor-c ...intermediate in the de novo synthesis of glycerolipids, it has been assumed that LPA synthesized by this route does not have a ... See full document

8

Epigenetic Activity of Peroxisome Proliferator-Activated Receptor Gamma Agonists Increases the Anticancer Effect of Histone Deacetylase Inhibitors on Multiple Myeloma Cells.

Epigenetic Activity of Peroxisome Proliferator-Activated Receptor Gamma Agonists Increases the Anticancer Effect of Histone Deacetylase Inhibitors on Multiple Myeloma Cells.

... major role in the development of multiple ...enhances, in-vitro, the cytotoxic effect of the Histone deacetylase inhibitor (HDACi), valproic acid (VPA), on multi- ple myeloma ... See full document

17

ISSN 1516-635X Oct - Dec 2015 Special Issue Nutrition - Poultry feeding additives 057-064 http:dx.doi.org10.15901516-635xSpecialIssue Nutrition-PoultryFeedingAdditives057-064 Effect of Cottonseed Meal Fermented with Yeast on the Lipid-related Gene Express

ISSN 1516-635X Oct - Dec 2015 Special Issue Nutrition - Poultry feeding additives 057-064 http:dx.doi.org10.15901516-635xSpecialIssue Nutrition-PoultryFeedingAdditives057-064 Effect of Cottonseed Meal Fermented with Yeast on the Lipid-related Gene Express

... used in poultry diets in ...effect of FCSM on lipid-related gene expression in ...number of males and females) were randomly divided into three groups, with six pens per group and 10 ... See full document

8

Effects of a PPARG gene variant on obesity characteristics in Brazil

Effects of a PPARG gene variant on obesity characteristics in Brazil

... contribution of genetic factors to the development of obesity has been widely recognized, but the identity of the genes involved has not yet been fully ...Variation in genes involved in ... See full document

6

Alternative Transcription of Peroxisome Proliferator-Activated Receptor Gamma in the Liver Is Associated with Fatness of Chickens

Alternative Transcription of Peroxisome Proliferator-Activated Receptor Gamma in the Liver Is Associated with Fatness of Chickens

... upregulated in “fat”chickens. The primer pairs used in that analysis, however, measured the expression of all gene transcripts (Larkina et ...design of transcript specific primers allowed us ... See full document

8

Avaliação do perfil de expressão gênica modulado pelo GQ-16 em adipócitos 3T3-L1 utilizando a técnica de microarranjo

Avaliação do perfil de expressão gênica modulado pelo GQ-16 em adipócitos 3T3-L1 utilizando a técnica de microarranjo

... o receptor retinóide x (Retinoid X Receptor - RXR), os receptores ativados por proliferadores peroxissomais (Peroxisome Proliferator-Activated Receptor - PPAR), o receptor ... See full document

167

Genetics of diabetic nephropathy

Genetics of diabetic nephropathy

... rates of hospitalization for all causes are about three times higher in patients with CKD than in those who do not have the disease ...indicator of high ...risk of developing DN and ... See full document

9

Nonalbuminuric Renal Insufficiency: Can It Be a Novel Category of Diabetic Nephropathy?

Nonalbuminuric Renal Insufficiency: Can It Be a Novel Category of Diabetic Nephropathy?

... Diabetic nephropathy is a major cause of chronic kidney disease (CKD) and a common underlying cause of ...hemodialysis. In or- der to prevent hemodialysis due to diabetic ... See full document

2

Advances in early biomarkers of diabetic nephropathy

Advances in early biomarkers of diabetic nephropathy

... level of GST in diabetic rats induced by streptozotocin was remarkably higher than in control rats, suggesting that hyperglycemia may be the major cause for elevated ...occurrence of DN ... See full document

8

In vitro and in vivo enhancement of adipogenesis by Italian ryegrass (Lolium multiflorum) in 3T3-L1 cells and mice.

In vitro and in vivo enhancement of adipogenesis by Italian ryegrass (Lolium multiflorum) in 3T3-L1 cells and mice.

... cultivated in South Korea to produce silage for domestic animals. Most of the farmers in South Korea have cultivated IRG as a feed for ruminants, because of its higher nutritive value and fast ... See full document

9

Medium Chain Fatty Acids Are Selective Peroxisome Proliferator Activated Receptor (PPAR) c Activators and Pan-PPAR Partial Agonists

Medium Chain Fatty Acids Are Selective Peroxisome Proliferator Activated Receptor (PPAR) c Activators and Pan-PPAR Partial Agonists

... LBD in a form that diffracts to relatively high resolution in the absence of exogenous ...amount of octanoic acid (OA, ...variations in activity relative to TZDs and MCFAs that bind ... See full document

10

Microparticles engineered to highly express peroxisome proliferator-activated receptor-γ decreased inflammatory mediator production and increased adhesion of recipient monocytes.

Microparticles engineered to highly express peroxisome proliferator-activated receptor-γ decreased inflammatory mediator production and increased adhesion of recipient monocytes.

... roles in atherosclerosis ...any of the aforementioned conditions were accumulating more lipid than ...increases of lipid uptake, THP-1 cells were directly transduced with PPARc-expressing lentivirus, ... See full document

25

Peroxisome proliferator-activated receptor-γ agonist 15d-prostaglandin J2 mediates neuronal autophagy after cerebral ischemia-reperfusion injury.

Peroxisome proliferator-activated receptor-γ agonist 15d-prostaglandin J2 mediates neuronal autophagy after cerebral ischemia-reperfusion injury.

... pg of 15-PGJ2 in the remaining ...B in neurons after cerebral I/R injury. (A) In sham-operated animals, cortical cells displayed diffuse and weak staining for LC3 in the ...granular ... See full document

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