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[PDF] Top 20 Single-cell states in the estrogen response of breast cancer cell lines.

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Single-cell states in the estrogen response of breast cancer cell lines.

Single-cell states in the estrogen response of breast cancer cell lines.

... identified the genes marking the inferred states (Fig. 6). In our top 50 ranked state-specific marker genes, we find many genes known to play a key role in the estrogen ... See full document

11

Estrogen induces Vav1 expression in human breast cancer cells.

Estrogen induces Vav1 expression in human breast cancer cells.

... Breast cancer is the most common death-causing cancer in females ...[1]. The persistent exposure to estrogen has been observed to closely correlate with the ... See full document

11

Receptor activator of NF-kB (RANK) expression in primary tumors associates with bone metastasis occurrence in breast cancer patients.

Receptor activator of NF-kB (RANK) expression in primary tumors associates with bone metastasis occurrence in breast cancer patients.

... member of the TNF receptor super family secreted by osteoblasts which, by competing with RANK for binding to RANKL, acts as a decoy receptor, thereby inhibiting osteoclastogenesis ...Alterations of ... See full document

9

Thyroid hormone status interferes with estrogen target gene expression in breast cancer samples in menopausal women

Thyroid hormone status interferes with estrogen target gene expression in breast cancer samples in menopausal women

... observed in breast cancer cell ...but the combination of T3 with TAM did not reverse gene expression levels to those observed in the untreated control group, ... See full document

9

Characterization of MTAP Gene Expression in Breast Cancer Patients and Cell Lines.

Characterization of MTAP Gene Expression in Breast Cancer Patients and Cell Lines.

... involved in anchorage-independent growth. This process is important for the progression of the disease, allowing the tumor to spread and ...observed in the more aggressive ... See full document

13

Vav1 fine tunes p53 control of apoptosis versus proliferation in breast cancer.

Vav1 fine tunes p53 control of apoptosis versus proliferation in breast cancer.

... protein in the hematopoietic system, where it is exclusively ...implicated in several human cancers, including lung, pancreatic and neuroblasoma. In this study, we analyzed the ... See full document

15

Alterações epigenéticas e do número de cópias do gene SFN em carcinomas mamários

Alterações epigenéticas e do número de cópias do gene SFN em carcinomas mamários

... to the current knowledge of the role of SFN gene in human cancer, new studies are clearly ...on in vitro approaches by using specific SFN gene disruption assays as well as ... See full document

104

Estrogen-Responsive Genes Overlap with Triiodothyronine-Responsive Genes in a Breast Carcinoma Cell Line

Estrogen-Responsive Genes Overlap with Triiodothyronine-Responsive Genes in a Breast Carcinoma Cell Line

... increase in the survival of hyperthyroid patients with breast cancer, whereas we have identified a biological link between breast cancer in postmenopausal women and ... See full document

8

Caracterização de linhagens derivadas de câncer de mama humano e avaliação do efeito induzido pelo paclitaxel sobre a susceptibilidade de células de câncer de mama à radiação gama

Caracterização de linhagens derivadas de câncer de mama humano e avaliação do efeito induzido pelo paclitaxel sobre a susceptibilidade de células de câncer de mama à radiação gama

... In the present work, two cell lines, MACL-1 and MGSO-3, from human primary breast cancer were characterized and the effect of paclitaxel on the radiation response of brea[r] ... See full document

2

PD-L1 expression is increased in a subset of basal type breast cancer cells.

PD-L1 expression is increased in a subset of basal type breast cancer cells.

... expression in basal cell lines could be confirmed in a larger ...shows the RMA expression level of PD-L1 for basal and non-basal breast cancer cell ... See full document

10

Dissertation submitted to Faculdade de Ciências Médicas Universidade Nova de Lisboa for the degree of Doctor in Oncology - Breast Cancer SandraMargaridaCaldasAmaral

Dissertation submitted to Faculdade de Ciências Médicas Universidade Nova de Lisboa for the degree of Doctor in Oncology - Breast Cancer SandraMargaridaCaldasAmaral

... increase the activity of Jun/Fos complexes, depending on the ER subtype and the specific ligand used (Figure ...that estrogen- or anti-estrogen-bound ER α complexes use AF-1 and ... See full document

136

Poly(alkylidenimine) Dendrimers Functionalized with the Organometallic Moiety [Ru(η

Poly(alkylidenimine) Dendrimers Functionalized with the Organometallic Moiety [Ru(η

... explore the in vitro cytotoxic potential of the metallodendrimers 3 and ...on the principle that only cells that are alive are metabolically active, that is, can reduce ...and in ... See full document

17

Prediction of cancer cell sensitivity to natural products based on genomic and chemical properties

Prediction of cancer cell sensitivity to natural products based on genomic and chemical properties

... role in cancer ...for the construction of novel drugs with enhanced antitumor ...relationship of natural products and obtained key structural properties, such as chemical bond or group, ... See full document

14

Molecular predictors of 3D morphogenesis by breast cancer cell lines in 3D culture.

Molecular predictors of 3D morphogenesis by breast cancer cell lines in 3D culture.

... interpretation of the morphological similarities based on their known molecular ...predictors. In an earlier paper [12], an extended set of similar data was analyzed manually, and four ... See full document

12

Paula Isabel Pereira Soares

Paula Isabel Pereira Soares

... is the immuno- genicity caused by a murine mAb, as above ...Most of these problems were overcome by replacing all or most of the constant regions of the murine mAb with human ... See full document

298

In vitro and in vivo antitumor activity of crude extracts obtained from Brazilian Chromobacterium sp isolates

In vitro and in vivo antitumor activity of crude extracts obtained from Brazilian Chromobacterium sp isolates

... to the genus Salinispora. The pattern emerged in a study that included global collection sites and this indicates that secondary metabolite production can be a species-specific phenotypic trait ... See full document

6

Application of Hyperthermia for Cancer Treatment: Synthesis and Characterization of Magnetic Nanoparticles and their internalization on Tumor Cell Lines

Application of Hyperthermia for Cancer Treatment: Synthesis and Characterization of Magnetic Nanoparticles and their internalization on Tumor Cell Lines

... on the injection of magnetic fluids directly into the tumor body, or into an artery supplying the tumor (Johannsen et ...2005). The method relies on the theory that after ... See full document

122

Frutalina, lectina αD galactose ligante de Artocarpus incisa L.: um estudo com câncer de mama

Frutalina, lectina αD galactose ligante de Artocarpus incisa L.: um estudo com câncer de mama

... Lectin binding properties of human breast cancer cell lines and human milk with particular reference for helix pomatia. agglutimin[r] ... See full document

121

Flavonoid Composition and Antitumor Activity of Bee Bread Collected in Northeast Portugal

Flavonoid Composition and Antitumor Activity of Bee Bread Collected in Northeast Portugal

... mixture of plant pollen, honey, and bee saliva that worker bees use as food for larvae, and for young bees to produce royal ...jelly. In the present study, five BB samples, collected from Apis ... See full document

12

Lucas de Barros Anastácio

Lucas de Barros Anastácio

... and cancer. Since the term synthetic phosphoethanolamine is not a descriptor, it was used as a keyword in the ...perform the search, the authors used the descriptor ... See full document

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