[PDF] Top 20 Studies of epithelial response to streptozotocin-induced hyperglycemia

... inclusion of lipid droplets and metabolic changes, despite being one of the causes of insulin resistance and consequent hyperglycemia (Mozaffari, Abdelsayed et ...models of NOD mice and ... See full document

... found to be more sensitive to autophagy than the ...diversity of autophagy responses in skeletal muscle may due to different regulation of protein synthesis and degradation in ... See full document

... Previous studies established that OA treatment also results in transcriptional effects that increase expression of several anti- oxidant defense genes, including a-tocopherol, glutathione perox- idase, ... See full document

... Previous studies by us demonstrated that estradiol and progesterone regulate a spectrum of uterine epithelial cell immune functions, including tight junction formation, cytokine and antimicrobial ... See full document

... used to assess cognitive function in ...shown to be sensitive to detect deficits in associative learning and memory of rats ...evidence of impaired spatial learning in diabetic animals, ... See full document

... between hyperglycemia and diabetic neuropathy has already been demonstrated in several studies and, among the theories proposed to its etiology, the oxidative stress stands out (Giuliano et ... See full document

... underlying hyperglycemia involves over-production (excessive hepatic glycogenolysis and gluconeogenesis) and decreased utilization of glucose by the ...Persistent hyperglycemia, the common ... See full document

... Loss of epithelial adhesion does not necessarily lead to full transition to a mesenchymal phenotype ...in response to TGF-b1 is mediated by the activation of a variety ... See full document

... subtype of non–small cell lung cancer (NSCLC). The presence of K-Ras mutation is associated with a poor prognosis, but no effective treatment strategies are available for K-Ras -mutant ...Epidemiological ... See full document

... 8% to 12% of diabetic pregnant women present with malformed fetuses, there is great interest in understanding the etiology, pathophysiological mechanisms, and treatment of gestational ...diabetes. ... See full document

... one of the chemical agents most com- monly used to induce experimental diabetic syndrome in ...tion of STZ induces hyperalgesia to thermal (5-9), mechan- ical (8-15) and chemical (8,11,16-18) ... See full document

... feature of diabetic cardiac autonomic neuropathy is a defective parasympathetic control, repre- sented by persistent resting tachycardia and loss of beat-to-beat variation during deep breathing (27), ... See full document

... able to covalently bind to SH groups, after a 3 hours incubation in presence or absence of 10 mM ...number of surface Figure ...Invasion of 9HTEo- and CFTE29o- by ...presence of ... See full document

... compared to untreated diabetic rats. T he methanolic leaf extract was also able to significantly deplete the total cholesterol concentration in treated STZ - induced diabetic ... See full document

... functioning of the heart and coronary artery as it relates with susceptibility to atherosclerosis ...effect of 100 mg/kg body weight of ALA on the concentrations of serum LDLC and HDLC ... See full document

... Induction of EMT-like features by immune cells has been shown in other ...able to induce ...80% of patients with relapsed breast cancer, induce hallmarks of EMT in vitro but show concurrent ... See full document

... (15ml) of sterile Nutrient agar was poured into each sterile petridish of equal size and allowed to ...surface of this sterile Nutrient agar plate was streaked with the pure culture of ... See full document

... effect of isoprenaline (0.1 μM) on the autocrine production of catecholamines was also evaluated by HPLC-ECD in the non-tumorigenic MCF-10A cell ...results of cell ...phenotype to one more ... See full document

... end of each experiment, body weight was again measured, and the rats were placed in metabolic cages for 24-h urine ...temperature to remove debris and used for determination of creatinine, total ... See full document

... cause of this pathology (Simões-Correia et ...loss of CDH1 expression is frequently associated with epigenetic events, such as promoter hypermethylation which have been considered a potential drug target, ... See full document