[PDF] Top 20 Transplantation of rat-derived microglial cells promotes functional recovery in a rat model of spinal cord injury

... identification of primary rat microglia ...Center of Qingdao City ...Hospital of Qingdao University Ethics Committee and the National Institutes of Health Guide for the Care and Use ... See full document

... ability of transplanted OPCs to retain their phenotype and mature post-transplantation was examined by double im- munostaining for human-nuclei and the oligodendrocyte-spe- cific markers Olig1 or adenomatous ... See full document

... number of other labs has performed spinal cord injury and ischemia models with G-CSF treatment alone, or in combination or control group with some sort of cellular ... See full document

... Differentiation of hMNPs in a SCI Model To investigate the reciprocal interaction between the injured spinal cord and a neuronal transplant population, the survival, differentiation, ... See full document

... totipotent cells, are biological therapies for ...cell transplantation for treatment of SCI has been studied for approximately 10 ...Undifferentiated cells are multipotent cells that ... See full document

... levels of chimerism in circulating myeloid cells were ...lack of immunosuppression elicited by BU, as the majority of circulating leukocytes are lymphoid cells, which are spared ... See full document

... present in MSC cultivation supernatant and determined that many interesting changes to protein levels occurred when CXCR4 was ...Numerous in vitro studies have shown that MSCs have low immunogenicity [61] ... See full document

... expansion of PDGFR-a and PDGFR-b expressing cell populations, with the strongest reductions being seen in the areas of the greatest tissue ...sources of CSPGs [40], ...reduction in ... See full document

... hand, in Diakonie, the ICF is used as a checklist to drive early intervention pro- grams for ...formance of the assessed child in an interactive environment recorded on video, is carried out by a ... See full document

... Spinal cord injury surgeries were performed on adult (8–12 week old) male C57BL/6 ...mixture of ketamine and xylazine (100 mg/kg and 10 mg/kg, respectively), after which they received a ... See full document

... expressed in identical cell populations by the central canal; their expression is restricted to lumen-contacting cells with motile cilia (9 þ 2 axonemes), and all such cells express both transgenes ... See full document

... Cell transplantation is a promising experimental treatment for spinal cord ...aim of the present study was to evaluate the efficacy of mononuclear cells from human umbilical ... See full document

... expression of NF-κBp65, HMGB1 were conducted by immunohistochemical ...China) in Tris-buffered saline (TBS) for 30 min at ...exception of the addition of the primary ... See full document

... Twenty four hours after hypoxia-ischemia, randomly selected rats received either HUCB cells or saline solution, both intravenously. Animals were anesthetized with halothane, the neck suture was open and left ... See full document

... differentiation of NSCs in this study is inconsistent with the general notion that the adult cord environment is constitutively unfavorable to the survival and differentiation of NSCs ... See full document

... counting of RGCs. Some of the rats (n = 6) in each group were chosen to receive RGCs labeling with BDA, which were conjugated with fluorescein ...injection of 2% pentobarbital sodium ... See full document

... flow of 10 mL/min with a peristaltic pump (Miniplus-2, Gilson Medical Electronics, ...pressure of 8 to 10 mmHg at the beginning of the ...immersed in a glass chamber kept at 37 °C by a water ... See full document

... life of bucket teeth in shovel and dragline deployed in handling of overburden rock is an important contributor to the stores cost and is also responsible for the loss of valuable ... See full document

... hUCBSCs ¼ human umbilical cord blood stem cells; MO ¼ Melissa officinalis; SCI ¼ spinal cord injury; SEM ¼ standard error of the mean; ANOVA ¼ analysis of variance.... There were no sign[r] ... See full document

... Proof of significant functional recovery comes from bet- ter knowledge of the spinal cord injury pathophysiology, anabolic and catabolic regulation factors, tissue ... See full document