[PDF] Top 20 Unexpected Regulatory Role of CCR9 in Regulatory T Cell Development.
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Unexpected Regulatory Role of CCR9 in Regulatory T Cell Development.
... blockade of CCR9 attenuates early intestinal inflammation [12,21], we first sought to examine the role of CCR9 in the pathogenesis of T cell-mediated colitis ... See full document
16
The Macrophage Galactose-Type C-Type Lectin (MGL) Modulates Regulatory T Cell Functions.
... the role of the C-type lectin MGL in the modulation of Treg functions via ...CD45RA. In our previous studies, we have shown the impor- tant role of this receptor in ... See full document
12
Late engagement of CD86 after influenza virus clearance promotes recovery in a FoxP3+ regulatory T cell dependent manner.
... response of conventional T effector cells [12] as well as to suppress inflammation through their ability to augment/sustain regulatory T cell (Treg) activity ...[13]. In the ... See full document
16
CD4+CD25hiCD127low regulatory T cells are increased in oral squamous cell carcinoma patients.
... subset of head and neck cancers occurs in about 400,000 individuals world-wide, and contribute to more than 222,000 deaths annually ...50% of oral cancer patients suffer from disease recurrence or ... See full document
10
Oral tolerance to cancer can be abrogated by T regulatory cell inhibition.
... inoculation of 2610 6 JBS tumour cells in Balb/C mice, tumours developed and were allowed to attain a size of 1–2 cm 3 , at which stage the animals were sacrificed and their tumours were ... See full document
11
Regulatory T cell expansion in HTLV-1 and strongyloidiasis co-infection is associated with reduced IL-5 responses to Strongyloides stercoralis antigen.
... Regulatory T cells are increasingly recognized as playing a key role in reducing injurious host inflammatory and immune responses ...[28]. Regulatory T cells control the immune ... See full document
8
Analysis of the transcriptional regulatory network: underlying heart development
... Heart development is a highly complex process with a series of precisely spatially and temporally ordered events on molecular ...out in the examination of single genes and their expression ... See full document
157
A gene regulatory network for root epidermis cell differentiation in Arabidopsis.
... gene regulatory pathway, we conducted WER::GFP-based FACS and transcriptome analyses with seven mutants defective in non- transcription-factor genes in the 208-gene ...group of genes ... See full document
20
Rapid regulatory T-cell response prevents cytokine storm in CD28 superagonist treated mice.
... activators of regulatory T-cells (Treg cells) in rats, but a first-in-man trial of the human CD28SA TGN1412 resulted in an unexpected cytokine release ... See full document
9
Regulatory CD4+Foxp3+ T cells control the severity of anaphylaxis.
... [21]. In this respect, we recently documented that anti-CD25 mAb injection before oral sensitization with a food allergen, enhanced both the priming of allergen-specific T and B cells and the ... See full document
9
Strong HIV-1-Specific T Cell Responses in HIV-1-Exposed Uninfected Infants and Neonates Revealed after Regulatory T Cell Removal
... sensitivity of this method is approximately 1%, we cannot preclude the possibility of the presence of maternal cells in compartments other than the ...fetus of an HIV-1-positive mother ... See full document
10
T Cell Subset in Host Homeostasis during Protozoan Infection: An Overview
... rates of morbidity and mortality ...persistence of parasites. Regulatory T cells (Treg), in particular the CD4 + CD25 + cell subset, appear to control the immune competence ... See full document
11
Inflammation Enhances the Risks of Stroke and Death in Chronic Chagas Disease Patients
... cause of death in Chagas disease ...component in all ischemic processes, including the intravascular events triggered by vessel interruption, brain damage and ...repair. In this study, we ... See full document
18
Foxp3+ regulatory T cells control persistence of viral CNS infection.
... regulatory T cells (Tregs) in autoimmune and pathogen-induced immune responses has been studied intensively during recent ...discovery of the transcription factor Foxp3 (forkhead box P3) as a ... See full document
8
Fetal development of regulatory mechanisms for body fluid homeostasis
... Most of Ang II-induced physiological responses ap- pear to be mediated by AT1 ...activation of central AT1 receptors, exerts hyperten- sive effects under normal conditions in the near-term ovine ... See full document
9
Development of regulatory T cells in the human thymus : one step beyond =desenvolvimento de células T reguladoras no timo humano
... Differentiation of blood-derived T cell progenitors to mature CD4 or CD8 T cells in the thymus is accomplished by sequential development through a series of stages that ... See full document
168
Physiological role of Kv1.3 channel in T lymphocyte cell investigated quantitatively by kinetic modeling.
... the regulatory mechanism of Kv1.3 channels in T cells, we constructed a model T-cell, composed of Figure ...Comparison of the recovery of ...currents ... See full document
9
Study of influence of regulatory polymorphisms of expression in development of breast cancer
... millions of genetics variants that can affect gene ...One of the diseases affected by cis-regulatory variants is breast ...one of the most common cancers, with approximately 4500 new cases ... See full document
48
T cell Maturation and Regulatory T Cell Differentiation: From the Thymus to the Periphery
... expressing regulatory T cells (Treg) are in control of pathological immune self reactivity and limit the immune response during infection ...generated in the thymus from developing ... See full document
226
Role of regulatory T cells in irinotecan-induced intestinal mucositis
... fixed in 10% neutral buffered formalin, dehydrated, and embedded in ...Sections of 5 μm thickness were obtained for hematoxylin-eosin staining (H&E) and subsequent ex- amination by light microscopy ... See full document
9
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