Brain development
How might cocaine interfere with brain development?
... W omen addicted to cocaine often continue drug use through pregnancy, despite risks to the fetuses they are carrying. Multiple studies have attempted to identify the effects of cocaine and other commonly abused drugs on ...
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Discovery of new candidate genes related to brain development using protein interaction information.
... process and mechanism of brain development is important. To explore this mystery, molecular and cellular biology approaches have widely been applied over the past decades and greatly ad- vanced our ...
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Selection and evaluation of reference genes for analysis of mouse (Mus musculus) sex-dimorphic brain development
... The development of the brain is sex-dimorphic, and as a result so are many neurological ...sex-dimorphic brain development is to measure gene expression in biological samples using ...of ...
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The role of thioredoxin reductases in brain development.
... most brain regions, including the olfactory bulb, subventricular zone and the cerebral cortex, did not reveal any histological abnormalities in Txnrd1-NS null mice, the cerebellar cortex displayed striking ...
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Visual maps in the adult primate cerebral cortex: some implications for brain development and evolution
... Figure 5. A, Flat-mounted vibratome slice through the brain of a marmoset. Caudal is towards the left, and dorsal towards the top. This slice has not been stained, and the borders of primary visual (V1) and middle ...
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Anesthetics rapidly promote synaptogenesis during a critical period of brain development.
... of development, both environmental, genetic and pharmacological interference with physiological neuronal activity can markedly and permanently alter wiring patterns and, thereby, information processing in the ...
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Neonatal disruption of serine racemase causes schizophrenia-like behavioral abnormalities in adulthood: clinical rescue by d-serine.
... found that neonatal Met-Phen administration causes PPI deficits in adult, but not juvenile stages, suggestive of maturation- dependent auditory sensory gating deficits. In addition, adult mice with neonatal Met-Phen ...
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The neonate was born with holoprosencephaly
... The pathogenesis of this disorder has been elucidated in a number of recent experimental studies on the neural tube and the identification of various gene mutations. Four genes, related to brain ...
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Rev. Bras. Psiquiatr. vol.35 suppl.2
... allow brain resistance to environmental influence – – ...different brain regions is a feature of several psychiatric ...during brain development) and/or altered regulation of these receptors ...
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Astrocyte heterogeneity in the brain: from development to disease
... affects brain development and results in progressive failure of central myelination, developmental delay, seizures, megalencephaly, and pro- gressive deterioration, with increased severity in neonatal ...
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Development of Cortical Morphology Evaluated with Longitudinal MR Brain Images of Preterm Infants.
... that brain development takes place in an occipital-frontal direction [43–46], which was confirmed by in vivo studies ...rapid development in the occipital lobes could explain the earlier functional ...
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Long-term effects of gestational nicotine exposure and food-restriction on gene expression in the striatum of adolescent rats.
... TO STRESS’’ would be enriched in ranked gene lists from the Con vs. Con-Pf and the Nic vs. Con-Pf comparisons. This was the case for the Con vs. Con-Pf comparison. As this analysis was not restricted to arbitrary ...
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Consequences of gestational diabetes to the brain and behavior of the offspring
... of brain development (Melo et ...to brain function, behavior and development of brain diseases could be expected in the offspring of GD (Figure ...in brain insulin signaling ...
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Consequences of gestational diabetes to the brain and behavior of the offspring
... Gestational diabetes mellitus (GD) is a form of insulin resistance triggered during the second/third trimesters of pregnancy in previously normoglycemic women. It is currently estimated that 10% of all pregnancies in the ...
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Thyroid hormone regulation of gene expression in primary cerebrocortical cells: role of thyroid hormone receptor subtypes and interactions with retinoic acid and glucocorticoids.
... on brain development and function are largely mediated by the binding of 3,5,39-triiodo-L- thyronine (T3) to its nuclear receptors (TR) to regulate positively or negatively gene ...
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Effects of lead andor zinc exposure during the second stage of rapid postnatal brain growth on delta- aminolevulinate dehydratase and negative geotaxis of suckling rats
... postnatal brain development on brain, kidney and blood ALA-D specific activity, as well as the negative geotaxis behavior of ...body, brain or kidney weights or brain- or kidney-to-body ...
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Psychol. Neurosci. vol.7 número2
... for brain development in both rodents and ...the development of which is concentrated during this developmental period, and thus impair memory ...
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Neuronal microRNA deregulation in response to Alzheimer's disease amyloid-beta.
... Normal brain development and function depends on microRNA (miRNA) networks to fine tune the balance between the transcriptome and proteome of the ...in brain where they play key roles in neuronal ...
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Microarray profiling and co-expression network analysis of circulating lncRNAs and mRNAs associated with major depressive disorder.
... normal brain development and function ...the development of ...the development of MDD, we used a microarray analysis profiling to identify genome-wide lncRNAs expression and co-expression ...
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Revisiting Inbred Mouse Models to Study the Developing Brain: The Potential Role of Intestinal Microbiota
... The brain is also very plastic in the first 2 years of life, the very same time period when children may be exposed to changing diets and contaminated environments, and afflicted with clinical and subclinical ...
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