Carbohydrate Binding
An adenovirus vector incorporating carbohydrate binding domains utilizes glycans for gene transfer.
... tandem carbohydrate binding domains found naturally in the C-terminus of the fiber of PAdV-4, NADC-1 isolate ...of carbohydrate binding domains is unique to PAdV-4 and is presumed to have ...
9
Conservation of carbohydrate binding interfaces: evidence of human HBGA selection in norovirus evolution.
... known carbohydrate-binding phenotypes of ...strains binding to either A/B/H antigens (A/B binding groups, yellow) or Lewis antigens (Lewis binding group, ...conserved binding ...
14
Licenciado Molecular Determinants of Ligand Specificity in Carbohydrate-Binding Modules: an NMR and X-ray crystallography integrated study
... the binding cleft area, which explains the negative results obtained by co- ...for binding are the ones at positions 2 and 6 of the central units of the ...and binding of these modules to various ...
409
Production of recombinant carbohydrate-binding modules in Pichia pastoris and their application in the modification of paper fibers
... Since the mid 1980s, enzymes have been widely applied in the paper industry, namely, in the bleaching boosting with xylanases and fiber modification with cellulases. Despite of the benefits of this utilization, the ...
105
A family 11 carbohydrate-binding module (CBM) improves the efficacy of a recombinant cellulase used to supplement barley-based diets for broilers at lower dosage rates
... 2. In general, plant cell wall hydrolases display a modular structure comprising a catalytic module linked to one or more non-catalytic carbohydrate-binding modules (CBMs). Based on primary structure ...
10
Fusing a carbohydrate-binding module into the Aspergillus usamii β-mannanase to improve its thermostability and cellulose-binding capacity by in silico design.
... 1 carbohydrate-binding module (CBM) of the Trichoderma reesei cellobiohydrolase I (TrCBH I), having the lowest binding free energy with cellobiose, was selected by in silico design, and fused into ...
8
Screening for carbohydrate-binding proteins in extracts of Uruguayan plants
... monomer N-acetylglucosamine did not inhibit HAG induced by the purified lectin, but chitobiose inhibited HAG at 24 mM and chitotriose inhibited it at 1 mM. ß-Galactosidase activity was detected in leaves and stems of ...
10
Deciphering ligand specificity of a Clostridium thermocellum family 35 carbohydrate binding module (CtCBM35) for gluco- and galacto- substituted mannans and its calcium induced stability.
... diverted binding may be ...this binding module may restore the potentialities of the hydrolytic ...Moreover, carbohydrate binding modules are used in various analytical ...this ...
11
The Carbohydrate-binding Specificity and Molecular Modelling of Canavalia maritima and Dioclea grandiflora Lectins
... The carbohydrate-binding specificity of lectins from the seeds of Canavalia maritima and Dioclea grandiflora was studied by hapten-inhibition of haemagglutination using various sugars and sugar de- ...
6
Structural Insight of a Trimodular Halophilic Cellulase with a Family 46 Carbohydrate-Binding Module.
... In contrast, the second CBM domain, CBM46, possesses multiple tryptophan, tyrosine and phenylalanine residues on the surface, which is a common feature for CBMs. The mutagenesis experiments indicate that the removal of ...
18
Molecular mechanisms of plant cell wall hydrolysis: developing novel biotechnological applications for carbohydrate-binding modules
... although binding affinities are lower for the latter ...ligand binding. It is suggested that the location of the three binding residues on the edge of the cleft may enable CBM30 and CBM44 to bind ...
200
Rev. LatinoAm. Enfermagem vol.20 número2
... novel carbohydrate- binding proteins is an open ield for many discoveries, as a possible involvement of these proteins in the tissue colonization ...
6
Dissertation to obtain Master degree in Biochemistry Supervisor: Maria Angelina de Sá Palma, UCIBIO, FCTUNL Co-supervisor: Ana Luísa Carvalho, UCIBIO, FCTUNL
... The carbohydrate microarray designated Fungal and Plant PS set1 used in this study has proven to be a valid tool for initial high-throughput screening of newly identified CBMs or CBMs assigned to known families in ...
159
A novel a-L-Arabinofuranosidase of Family 43 Glycoside Hydrolase (Ct43Araf ) from Clostridium thermocellum
... The molecular architecture of family 43 glycoside hydrolase (Ct43Araf) from C. thermocellum displays an N-terminal family 43 glycoside hydrolase catalytic module (CtGH43, 903 bp) followed by two successive ...
10
The immune role of C-type lectins in molluscs
... Besides non-self recognition, molluscan lectins participate in innate immune responses, including agglutination, hemocyte phagocytosis as well as encapsulation, and even bactericidal effect (Wang et al., 2007; Zheng et ...
6
The active site of a carbohydrate esterase displays divergent catalytic and noncatalytic binding functions.
... noncatalytic carbohydrate binding ...noncatalytic binding to cellulose whilst the active site of the domain retains its esterase ...noncatalytic binding functionality into the active site of ...
11
The zinc transporter, Slc39a7 (Zip7) is implicated in glycaemic control in skeletal muscle cells.
... Intracellular zinc homeostasis is largely regulated by two families of zinc transporters (ZnTs and ZIPs) that traffic zinc across biological membranes [35,36]. Dysregulation of zinc signaling leads to a number of disease ...
15
Comparative analyses of lipoprotein lipase, hepatic lipase, and endothelial lipase, and their binding properties with known inhibitors.
... The binding pockets of LPL and HL are quite different, as mentioned above (see Figure 10a and Figure ...The binding pocket of LPL is large compared with the size of CHEMBL339297, meaning that their ...
15
Dystrophin is a microtubule-associated protein
... An indirect link between dystrophin and MTs mediated by ankyrinB was recently shown to be important for proper trafficking of dystrophin and dystroglycan to the sarcolemma (Ayalon et al., 2008). However, costameric ...
7
Carbohydrate metabolism and metabolic disorders in horses
... hydrolyzable carbohydrate and the appearance of enhanced SGLT1 was 12 to 24 h in mice (Ferraris and Diamond, ...hydrolyzable carbohydrate, so direct comparisons should be considered with ...hydrolyzable ...
7