Mutation Rate
Cryptic variation in the human mutation rate.
... the mutation rate, we fit two models to the ratio of the observed number of coincident SNPs over the number expected with simple context ...the mutation rate was log-normally distributed; in ...
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An analysis of the spontaneous mutation rate measurement in filamentous fungi
... As pointed out by Fincham and Day (1971), the ideal in this case would be “to measure the chance of mutation occurring per nucleus per time unit, or per nuclear genera- tion time.” This is possible in organisms ...
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Microsatellite frequencies vary with body mass and body temperature in mammals, suggesting correlated variation in mutation rate
... microsatellite mutation rate increases with repeat number, trend strength tends to increase with repeat number (Weber, 1990; Kelkar et ...the mutation rate of short microsatellites, which may ...
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Mutation rate switch inside Eurasian mitochondrial haplogroups: impact of selection and consequences for dating settlement in Europe.
... single mutation event. This absence of mutation is more likely to have occurred only once, before the divergence of the R0sublineages, ...the mutation rate was unmodified, it would be possible ...
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Porcine circovirus 2b: isolations and mutation rate in J744 lineage macrophage cell
... ABSTRACT: Porcine circovirus 2 (PCV2) is associated with various clinical signs that are collectively designated as Circovirosis and has a great impact on the pig industry. The virus isolation is classically performed on ...
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Whole genome sequencing of mutation accumulation lines reveals a low mutation rate in the social amoeba Dictyostelium discoideum.
... nuclear mutation described ...a mutation rate, because it exhausted all possible mutations within two ...lower mutation rate ...one mutation accumulation line, and unchanged ...
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Variation in RNA virus mutation rates across host cells.
... average mutation rate did not significantly differ from the rate obtained in BHK-21 cells (m = ...VSV mutation rate in BHK-21 cells cultured under hypoxic conditions (1% oxygen) was ...
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Stochastic drift in mitochondrial DNA point mutations: a novel perspective ex silico.
... Mitochondria are the main energy producing organelles present in eukaryotic cells. Mitochondria are the only organelles aside from the nucleus which harbor their own genetic material. Mitochondrial DNA (mtDNA) encodes a ...
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Braz. J. Phys. vol.34 número3B
... male mutation rate is larger than the female one, and so neither Nature nor the model allows females to die sooner from accumulated genetic mutations than the ...
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Exploiting the Adaptation Dynamics to Predict the Distribution of Beneficial Fitness Effects.
... different rate of ...high mutation rate regime as well, where α values are slightly larger in all ...high mutation regime, in the case of Weibull distributions, fitness reaches a plateau in ...
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TCA cycle-mediated generation of ROS is a key mediator for HeR-MRSA survival under β-lactam antibiotic exposure.
... the rate of spontaneous mutation ...increased mutation rate during b-lactam- mediated HeR/HoR selection involved the induction of LexA/ RecA-mediated SOS response ...
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Polymorphic sequence in the ND3 region of Java endemic Ploceidae birds mitochondrial DNA
... Mitochondrial DNA (mtDNA) are easily extracted, relatively small size (Shadel and Clayton 1997), has a mutation rate ten times faster than nuclear DNA (Christianti et al. 2003), and contain more variation ...
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Arq Bras Endocrinol Metab vol.58 número8
... a mutation in the sodium iodide symporter (NIS) ...NIS mutation rate is very low in the Guangxi Zhuang Autonomous Region, China, and it is necessary to study mutations of other genes that have major ...
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Flavobacterium sp. by Supercritical CO2
... positive mutation rate for each treatment was calculated as the number of the positive mutant strains divided by the number of all selected strains on the corresponding agar medium ...
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Population expansion in the North African Late Pleistocene signalled by mitochondrial DNA haplogroup U6
... a mutation rate estimate for the complete mtDNA sequence of one transition in every 3,624 years [31], cor- recting for purifying selection by using the calculator provided with that ...HKY85 mutation ...
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GAHC: Improved GA with HC mutation
... 3. applying of the HCA on the kernel, using the entire individual for objective function evaluation. The individual, kernel position and kernel size can be chosen randomly or based on some heuristic, that could exploit ...
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Danish type gelsolin-related amyloidosis in a Brazilian family: case reports
... This mutation has been reported in all Finnish patients as well as in other ...second mutation is a 654G-T transver- sion resulting in a Asp187Tyr substitution and was found in only three families, of ...
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Rev. Bras. Hematol. Hemoter. vol.31 número3
... mutation, but both studies include reduced number of individuals, 159 and 160, respectively. Due to the importance of both hereditary thrombophilias as risk factors of venous thrombosis, it seems necessary to know ...
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Arq Bras Endocrinol Metab vol.58 número6
... We present the irst report of 3b-hydroxy-steroid dehydrogenase type II deiciency genotype-proven de- tected at the Newborn Screening Program in Brazil. The clinical and hormonal features of a 46, XY infant with a ...
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Arq Bras Endocrinol Metab vol.54 número1
... there was a positive family history for non-neoplastic thyroid disease. There was no history of previous radia- tion on her cervical region. On physical examination, she weighed 54 kg and was 160 cm tall (body mass in- ...
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