Systemic Sclerosis (SE)
Mantle cell lymphoma and systemic sclerosis
... Systemic sclerosis (SSc) is a rare disease with an in- creased incidence of cancer, but the ocorrence of Non- -Hodgkin lymphoma (NHL) is a very uncommon ...
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Systemic sclerosis, a rare case
... phenomena, complicated by digital ulcer of the third finger of her right hand (aggravated by her job). She also referred symmetrical inflammatory polyarthralgias, namely in the wrists, hands, knees and ankles. At ...
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Correlation between serum E-selectin levels and panoramic nailfold capillaroscopy in systemic sclerosis
... neutrophils (7). E-selectin mediates a neutro- phil adhesion pathway distinct from that medi- ated by ICAMs and leukocyte integrins and participates in early steps of neutrophil binding to the endothelium, before ...
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Systemic sclerosis in a patient with pityriasis rubra pilaris
... findings. Systemic sclerosis is diagnosed on the basis of skin thickening, sclerodactyly, acroosteolysis and presence of anti-nucleolar antibodies, although there was no evidence of objective ...
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Identification of NF-kappa B and PLCL2 as new susceptibility genes and highlights on a potential role of IRF8 through interferon signature modulation in systemic sclerosis
... Systemic sclerosis (SSc) is an autoimmune disease (AID) characterized by vascular damage, autoantibody produc- tion, and fibrotic events. SSc is an orphan disease that is considered the most severe ...
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Assessment of light touch sensation in the hands of systemic sclerosis patients
... RESULTS: Statistically significant differences were found between groups in the monofilament test. The study group had lower scores across all points of the hand when compared with the control group. Differences were ...
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Clinical and radiographic study of orofacial alterations in patients with systemic sclerosis
... Abstract: Systemic sclerosis (SS) is an autoimmune disease with great repercussions on the hard and soft tissues of the orofacial ...with systemic sclerosis and 10 healthy ...
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Th17 pathway genes polymorphisms in Algerian patients with systemic sclerosis
... Among the two studied single nucleotide polymor- phisms of IL-17F, only the rs2397084 SNP was associa - ted with the susceptibility to systemic sclerosis (SSc) with p = 0,049 and p = 0,036 for the TT ...
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Trigeminal sensory neuropathy associated with systemic sclerosis: report of three Brazilian cases
... 5. Mayes MD, Lacey JV, Beebe-Dimmer J, et al. Prevalence, inci- dence, survival, and disease characteristics of systemic sclerosis in a large US population. Arthritis Rheum 2003;48:2246-2255. 6. Hagen NA, ...
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A possible contribution of altered cathepsin B expression to the development of skin sclerosis and vasculopathy in systemic sclerosis.
... Cathepsin B (CTSB) is a proteolytic enzyme potentially modulating angiogenic processes and extracellular matrix remodeling. While matrix metalloproteinases are shown to be implicated in tissue fibrosis and vasculopathy ...
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Lidocaine for systemic sclerosis: a double-blind randomized clinical trial
... ANOVA: Analysis of variance; ACR: American College of Rheumatology; CONSORT: Consolidated Standards of Reporting Trials; (F): Fischer’s exact test; FAPESP: State of Sao Paulo Research Support Foundation [Fundação de ...
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Clinical Presentation and Long-Term Outcomes of Systemic Sclerosis Portuguese Patients from a Single Centre Cohort: A EUSTAR Registration Initiative
... for systemic sclerosis) under current follow-up, divided according to the LeRoy classification into diffuse cutaneous (n = 5), limited cutaneous (n = 11) and limited (n = 3) types, followed for a median ...
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Matrix metalloproteinase 7 is a candidate biomarker in systemic sclerosis-associated interstitial lung disease
... Background: Pulmonary complications, including pul- monary fibrosis, are the leading causes of death in sys- temic sclerosis (SSc). However, the aetiology and patho- physiologic mechanisms of the disease have not ...
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Prevalence and clinical manifestations of Erasmus syndrome in systemic sclerosis: a cross-sectional study
... Introduction: Erasmus syndrome (ErS) is a rare entity in which Systemic Sclerosis (SSc) develops following exposure to silica, with or without associated silicosis. The objectives of this study were: 1) to ...
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The clinical significance of antibody determination to cyclic citrullinated peptides in systemic sclerosis
... of systemic sclerosis with some joint manifestations, which leads to a conclusion that a high titer of these anti- bodies can predict patients with overlap syndrome – SSc and ...
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Autoantibodies in systemic sclerosis: unanswered questions
... Systemic sclerosis (SSc) is an autoimmune disease characterized by vascular abnormalities, and cutaneous and visceral fibrosis. Serum autoantibodies directed to multiple intracellular antigens are present ...
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Systemic Sclerosis: know more, hope more
... Systemic Sclerosis (SSc) is characterized by vascular inflammation, vascular hyper-reactivity and excess tis- sue collagen deposition. These pathologic changes lead to macro and microvascular injury and to ...
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Systemic sclerosis: markers and targeted treatments
... Systemic sclerosis (SSc) is characterized by autoanti- body production, progressive microvasculopathy, and aberrant extracellular matrix protein (ECM) synthesis in ...
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Capillaroscopy 2016: new perspectives in systemic sclerosis
... Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by early impairment of the microvascular system. Nailfold microangiopathy and decreased peripheral blood perfusion are ...
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Tradução, adaptação cultural e validação para a língua portuguesa (Brasil) do Systemic Sclerosis Questionnaire (SySQ).
... A versão na língua portuguesa do SySQ mostrou-se re- produtível e válida para uso em nossa população, utilizan- do metodologia reconhecida para tradução e adaptação cultural de question[r] ...
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