Therapeutic response
ULK1: a promising biomarker in predicting poor prognosis and therapeutic response in human nasopharygeal carcinoma.
... We know that the maliganent cells always have a high demand for nutrient and oxygen to facilitate their high proliferation rate during tumor development and progression. However, during the long term of therapy courses, ...
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Assessment of Therapeutic Response of Plasmodium vivax and Plasmodium falciparum to Chloroquine in a Malaria Transmission Free Area in Colombia
... parasitological response, graded as RIII, RII, early RI, and late RI/sensitive (WHO 1996), and (2) therapeutic response, according to the following classification: (a) early treatment failure (ETF), ...
4
Hepatitis C: A Critical Analysis of Therapeutic Response Predictors
... unfavorable therapeutic response include: 1) viral genotype; 2) cirrhosis; 3) HCV-HIV co-infection; 4) elevated iron overload; 5) high viral load; 6) immunosuppressive conditions, such as alcoholism, ...
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The importance of low molecular weight protein tyrosine phosphatase in the progression of metastatic bone disease and therapeutic response
... Bone metastases are an excellent example of how the tumor needs the host and its microenvironment. Bone tissue is a specialized connective tissue rich in growth factors and cytokines, providing an excellent soil for ...
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Soluble Inflammatory Markers as Predictors of Hepatocellular Damage and Therapeutic Response in Chronic Hepatitis C
... immune response, especially T helper type 1 (Th1) cell-mediated, seems to play an important role in disease progression but is also crucial for viral elimination following specific ...and therapeutic ...
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18FDG PET/CT in the qualitative and quantitative evaluation of the therapeutic response in Hodgkin’s lymphoma
... a Sussex Cancer Centre, Brighton and Sussex University Hospitals NHS Trust, Brighton, UK, b Department of Medical Imaging and Nuclear Medicine, Brighton and Sussex University Hospital. [r] ...
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Health related quality of life in patients with refractory chronic heart failure undergoing cardiac resynchronization: type of therapeutic response
... associated with improvement of HRQL. Conclusion: In a population with severe CHF undergoing CRT, the patients with clinical and echocardiographic positive response, obtained a favorable impact in all dimensions of ...
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The c.-1639g>A polymorphism of the VKORC1 gene and his influence on the therapeutic response during oral anticoagulants use
... Background/Aim. A single nucleotide polymorphism c.- 1639G>A in the promoter region of vitamin K-epoxide reductase (VKORC1) gene has been found to account for most of the variability in response to oral ...
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Fibroblasts Influence Survival and Therapeutic Response in a 3D Co-Culture Model.
... a response to therapeutic compounds in vitro that correlates with and may provide potential pre- dictive value with regard to the clinical response[16, ...
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Granuloma faciale: a good therapeutic response with the use of topical tacrolimus
... zone separating the nodular dermal inflammatory infiltrate, composed predominantly of lymphocytes, histiocytes, neutrophils and numerous eosinophils (Figure 2). Based on the clinical picture and the his- tological ...
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Morbihan disease: a therapeutic challenge
... variable therapeutic response and great ...excellent therapeutic response with the combination of deflazacort and oral isotretinoin but developed recurrence after corticosteroid ...
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Angiogenesis as a Therapeutic Target in Endometriosis
... Results: The present review provides a concise summary of the known molecular mechanisms that promote vascularization of endometriotic lesions and may serve as potential therapeutic targets. We also present a ...
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New therapeutic approaches for bone regeneration
... Together, our results demonstrate that the produced β-TCP/HA structures are highly porous, hydrophilic, biocompatible and resistant to compression, improvements particularly achieved for the 80/20 structure. It was also ...
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Protein-biomembrane interactions as therapeutic targets
... To study the interaction of the peptides with the cell membranes, we could not use the same methodology as on the pre- vious studies with biomembrane model systems (ch[r] ...
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Novel Antiretroviral Therapeutic Strategies for HIV
... When the first cases of HIV infection first surfaced in the 1980s, AIDS was a deadly disease without any therapeutic alternatives. Currently, there is still no cure for the most cases mainly due to the multiple ...
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Designing of Nanocarriers for Therapeutic Applications
... Nanotechnology is a developing area in science and technology that is being widely explored during the last decade and is one of the most important areas related to drug delivery, cancer treatment and diagnosis. The ...
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Erosive lichen planus: a therapeutic challenge
... were immunosuppressant drugs, which were used in 8.87% of cases. Azathioprine appeared to be the most effective, with complete resolution observed in 75% of cases and no recurrence reported up to 9 months after ...
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Novel therapeutic approaches for skin regeneration
... Therefore, it was possible to conclude that from the MAC:MAG hydrogels, the hydrogel with more chitosan content (2:1) was the only one that significantly improved the fibroblast cells [r] ...
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Therapeutic Target Identification for Lung Cancer
... The key challenge facing a disease PPI network is the identification of a node which is related to potential drug target. To address these questions, we first collected lung cancer associated genes and hypothesized that ...
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Iron as therapeutic target in human diseases
... effective. Nevertheless, new approaches targeting hepcidin levels could be useful to better control iron parameters and especially some symptoms of this disease, like arthritis. The work by Porto et al. [ 13 ] described ...
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