[PDF] Top 20 A long non-coding RNA regulating cellular reprogramming
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A long non-coding RNA regulating cellular reprogramming
... a non-coding RNA (ncRNA). Contrary to messenger RNA (mRNA), ncRNAs do not code for a protein nor are translated into one (Huttenhofer et ...of non-coding transfer RNAs (tRNAs) ... See full document
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Long Non-Coding RNA MALAT1 Mediates Transforming Growth Factor Beta1-Induced Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells.
... largest cellular component of the epiretinal membranes in PVR patients ...whether long non- coding RNAs (LncRNAs) contribute to EMT of RPE ... See full document
15
Long non-coding RNA expression profiling of mouse testis during postnatal development.
... As previously mentioned, lncRNAs are often coordinately transcribed with their associated protein-coding transcripts and can regulate the expression of their adjacent or overlapping protein-coding genes in ... See full document
13
Long non-coding RNA LINC00261 sensitizes human colon cancer cells to cisplatin therapy
... Cisplatin resistance has been reported to be an obstacle for treatment of multiple cancers and has been studied for decades in various cancer therapies (18,19). Many factors have been reported to be responsible for ... See full document
9
Exploiting the role of long non-coding RNAs in the direct conversion of fibroblasts into functional cardiomyocytes
... in regulating cardiac chromatin structure during heart development and pathological remodeling (Schonrock et ...regulates cellular and systemic cholesterol homeostasis and conversely, CHROME expression is ... See full document
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Integration of expressed sequence tag data flanking predicted RNA secondary structures facilitates novel non-coding RNA discovery.
... other cellular differentiation related contexts with similar effects, such as during the formation of multiple blood cell lineages during hematopoiesis [56] and during hepatic stem cell differentiation [57], being ... See full document
11
The long non-coding RNA ADAMTS9-AS2 was identified as a potential prognostic biomarker in triple-negative breast cancer / O RNA longo não codificador ADAMTS9-AS2 foi identificado como um potencial biomarcador prognóstico no câncer de mama triplo negativo
... For instance, the lncRNA H19, expressed only in the mother-inherited chromosome, is detected both in the nucleus and cytosol and is related to several biological processes such as inflammation, apoptosis, and ... See full document
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Long Non-Coding RNA Malat-1 Is Dispensable during Pressure Overload-Induced Cardiac Remodeling and Failure in Mice.
... the cellular level, knockdown of Malat-1 results in alternative splicing of several genes [14], and in line with this, it was found that Malat-1 co- localizes with the splicing factors ASF/SF2 in nuclear speckles ... See full document
12
Association of long non-coding RNA MIAT and MALAT1 expression profiles in peripheral blood of coronary artery disease patients with previous cardiac events
... consistent with the hypoxia-induced up-regulation of lncRNA MALAT1 seen in ischemic limbs (Watts et al., 2013). Recently, Sallé-Lefort et al. (2016) indicated that the enhanced MALAT1 gene transcription upon low oxygen ... See full document
10
Knockdown of long non-coding RNA ANRIL inhibits tumorigenesis in human gastric cancer cells via microRNA-99a-mediated down-regulation of BMI1
... Long non-coding RNA antisense non-coding RNA in the INK4 locus (ANRIL) has been reported to promote tumorigenesis via regulating microRNA (miR)-99a in gastric ... See full document
10
Study of the Long Non-Coding RNA C/EBPβ-AS in Cutaneous Melanoma
... The MAPK/ERK pathway is one of the primordial signalling systems present in all eukaryotes, controlling such fundamental cellular processes as cell proliferation, differentiation, senescence, survival and ... See full document
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Long non-coding RNA CHCHD4P4 promotes epithelial-mesenchymal transition and inhibits cell proliferation in calcium oxalate-induced kidney damage
... The hierarchical clustering showed systematic differ- ences in the expression of lncRNAs and protein-coding RNAs between the kidneys of the mice administered glyoxylate and those in the control group (Figure 2A). ... See full document
11
Elementary screening of lymph node metastatic- related genes in gastric cancer based on the co-expression network of messenger RNA, microRNA and long non-coding RNA
... by regulating MMP7 ...endogenous RNA to regulate HER2 expression by sponging MiR-331-3p (12), HMlincRNA717 may play crucial roles during cancer occurrence and progression (8), and ATB plays an impor- tant ... See full document
10
Long non-coding RNAs as potential therapeutic targets in human breast cancer
... neighboring coding transcript on the opposite strand are initiated in close genomic proximity; (4) intronic, when derived from an intron of a second transcript; or (5) intergenic, when it is an independent unit ... See full document
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Detection of long non-coding RNA in archival tissue: correlation with polycomb protein expression in primary and metastatic breast carcinoma.
... of long non-coding RNAs (lncRNAs) is regulating gene expression through changes in chromatin ...project, RNA in situ hybridization of probes to three different lncRNAs (HOTAIR, ncHoxA1, ... See full document
8
Long non-coding RNA HOTAIR promotes UVB-induced apoptosis and in flammatory injury by up-regulation of PKR in keratinocytes
... Excessive exposure to ultraviolet (UV) rays can cause damage of the skin and may induce cancer, immunosuppression, photo- aging, and inflammation. The long non-coding RNA (lncRNA) HOX antisense ... See full document
11
Long non-coding RNA-ROR aggravates myocardial ischemiareperfusion injury
... To further illustrate the underlying molecular mech- anism for apoptosis, which is mediated by lncRNA-ROR, MAPKs such as p38 and ERK were measured. Several studies have indicated that activation of p38 occurs during I/R ... See full document
10
Long non-coding RNA contributes to direct conversion reprogramming
... however reprogramming procedures face other limitations such as low reprogramming efficiency, particularly in iPSC reprogramming where efficiency usually doesn’t get over 1% and though direct ... See full document
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Non-Coding RNAs : multi-tasking molecules in the cell
... of RNA molecules for cell function started to push them to the limelight, but the complexity of their roles and the wide variety of molecular mechanisms where RNA molecules are critical players was still ... See full document
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Enhancing reprogramming and transdifferentiation through long non-coding RNAs
... Long Non-coding RNAs (lncRNAs) are transcripts with more than 200 nucleotides that don’t encode proteins but have an important role in gene expression regulation and protein synthesis, such as, ... See full document
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