[PDF] Top 20 Arq Bras Endocrinol Metab vol.51 número5

... A ÚLTIMA DÉCADA TROUXE importantes avanços no entendimento da patogênese do câncer da tiróide, assim como na conduta que uti- lizamos para o diagnóstico da doença e tratamento dos pacien[r] ... See full document

... Apoptosis is an essential physiological process of elimination of destined cells during the development and differentiation or after damage from external stresses such as ionizing radiation or chemotherapeutic agents. ... See full document

... Mutações no BRAF surgiram recentemente como potenciais marcadores prognós- ticos do carcinoma papílifero de tiróide (CPT) graças a vários estudos que su- gerem que ele possa condicionar o desenvolvimento de tumores com ... See full document

... There are also new approaches for surveillance of patients with an established diagnosis of thyroid cancer, and their refine- ment is leading to the observation that many patients, previ[r] ... See full document

... This review is focused on “new drugs” that might be developed for thyroid cancer treatment. Thyroid cancer is frequently associated to the activation of specific protein (RET, BRAF) and lipid [PI(3)K] kinases. There is ... See full document

... gia (TLE) e alcance limitado. Ensaios clínicos estão sendo conduzidos em pacientes com glioblastoma multiforme e melanoma, e nós estamos exploran- do sua possível aplicação no CIT. Nossos resultados demonstram que uma ... See full document

... Serum calcitonin is a well-established sensitive and spe- cific marker for MTC. Therefore all patients undergo- ing thyroidectomy for MTC should be followed with postoperative serial serum calcitonin levels to survey for ... See full document

... first FDG-PET caveat is that careful imaging of the neck should be performed before obtaining an FDG- PET scan. Regional lymph nodes are the most com- mon and most treatable site of PTC metastasis. For most medical ... See full document

... It is necessary to emphasize that the Belarusian experience with childhood thyroid cancers has been more substantial as compared to that in Ukraine and affected regions of Russian Federation, especially in terms of the ... See full document

... The RET/PTC oncogene has been isolated almost twenty years ago. During these years, the research has given a final answer to several questions. In fact, it has been demonstrated that: a) RET/PTC is an early event in the ... See full document

... Thyroid cancers are the most frequent endocrine neoplasms and mutations in the thyrotropin receptor (TSHR) are unusually frequent. Here we present the state-of-the-art concerning the role of TSHR in thyroid cancer and ... See full document

... O carcinoma papilífero de tireóide (CPT) é o tipo mais prevalente de câncer endócrino e, em pesquisas epidemiológicas recentes, um dos tipos de câncer humano cuja incidência vêm crescendo. A despeito do prognóstico ... See full document

... A glândula tireóide tem capacidade de captar e concentrar iodeto, etapa fundamental na biossíntese dos hormônios tireóideos. O uso de iodo radioativo para fins de diagnóstico e terapia das doenças da tireóide vem sendo ... See full document

... Iodine is a trace element that is essential for the synthesis of thyroid hormone. Both chronic iodine deficiency and iodine excess have been associated with hypertrophy and hyperplasia of follicular cells, attributed to ... See full document

... O uso cada vez mais freqüente de métodos diagnósticos simples e efetivos tem contribuído significativamente para um aumento no diagnóstico de câncer da tiróide nos últimos anos. Entretanto, existem importantes evidências ... See full document

... The term ‘occult’ EAS was introduced for those cases with unequivocal non-pituitary CS in which the source of ectopic ACTH secretion was not obvious (8). However, this term may no longer be suitable, as recent ... See full document

... Primary pigmented nodular adrenocortical disease (PPNAD) is a form of bilateral adrenocortical hyperplasia that is often associated with corti- cotrophin (ACTH)-independent Cushing’s syndrome (CS) and is character- ized ... See full document

... Multiple endocrine neoplasia type 2 (MEN2) is an autosomal dominant inherited tumor syndrome caused by RET proto-oncogene germline muta- tions (RET). Here we tested the Conformation Sensitive Gel Electrophoresis (CSGE) ... See full document

... Bracci E, et al. A reappraisal of the role of methimazole and other factors on the efficacy and outcome of radioiodine ther- apy of Graves’ hyperthyroidism. J Clin Invest 1990;13:513. 11. Andrade VA, Cross JL, Maia AL. ... See full document

... (Arq Bras Endocrinol Metab 2007;51/8:1226-1237) Descritores: Hiperplasia adrenal macronodular independente de ACTH (AIMAH); Receptores adrenais aberrantes; Síndrome de ... See full document