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[PDF] Top 20 Development and validation of a prognostic gene-expression signature for lung adenocarcinoma.

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Development and validation of a prognostic gene-expression signature for lung adenocarcinoma.

Development and validation of a prognostic gene-expression signature for lung adenocarcinoma.

... several prognostic signatures have been developed in lung cancer, their application in clinical practice has been limited because they have not been validated in multiple independent data ...lack of ... See full document

10

Development and Validation of a Gene-Based Model for Outcome Prediction in Germ Cell Tumors Using a Combined Genomic and Expression Profiling Approach.

Development and Validation of a Gene-Based Model for Outcome Prediction in Germ Cell Tumors Using a Combined Genomic and Expression Profiling Approach.

... (IGCCCG) prognostic classification, which is based on histology (seminoma [SEM] versus non-seminoma [NSGCT]), serum marker levels of alpha-fetoprotein (AFP), human chorionic gonadatropin (HCG), and ... See full document

13

MicroRNA-650 was a prognostic factor in human lung adenocarcinoma and confers the docetaxel chemoresistance of lung adenocarcinoma cells via regulating Bcl-2/Bax expression.

MicroRNA-650 was a prognostic factor in human lung adenocarcinoma and confers the docetaxel chemoresistance of lung adenocarcinoma cells via regulating Bcl-2/Bax expression.

... targets of miR-650 were predicted through at least three databases (Pictarget, miRBas and TargetScan), and ING4 was selected as a putative target, which was also recently reported in gastric cancer ... See full document

16

Gene expression classification of colon cancer into molecular subtypes: characterization, validation, and prognostic value.

Gene expression classification of colon cancer into molecular subtypes: characterization, validation, and prognostic value.

... recurrence, and to date, no gene expression signature has proven reliable for prognosis stratification in clinical practice, perhaps because CC is a heterogeneous ...aim of this study ... See full document

13

MicroRNA-dependent regulation of transcription in non-small cell lung cancer.

MicroRNA-dependent regulation of transcription in non-small cell lung cancer.

... regulation of almost every cellular process investigated and that changes in their expression are observed in diseases such as ...30% of all protein-coding genes ...the development ... See full document

13

Identification of Subtype-Specific Prognostic Genes for Early-Stage Lung Adenocarcinoma and Squamous Cell Carcinoma Patients Using an Embedded Feature Selection Algorithm.

Identification of Subtype-Specific Prognostic Genes for Early-Stage Lung Adenocarcinoma and Squamous Cell Carcinoma Patients Using an Embedded Feature Selection Algorithm.

... keywords of feature selection and RNA-seq, the search only returned 11 articles while the number was 358 after the keyword of RNA-seq being replaced by microarray (dated Jan 12, ...lag of ... See full document

10

CAFET algorithm reveals Wnt/PCP signature in lung squamous cell carcinoma.

CAFET algorithm reveals Wnt/PCP signature in lung squamous cell carcinoma.

... the gene expression patterns of 138 Non-Small Cell Lung Cancer (NSCLC) samples and developed a new algorithm called Coverage Analysis with Fisher’s Exact Test (CAFET) to identify ... See full document

11

A simple but highly effective approach to evaluate the prognostic performance of gene expression signatures.

A simple but highly effective approach to evaluate the prognostic performance of gene expression signatures.

... is validation in multiple independent ...random signature is called prognostic dramatically (Figure ...a gene signature in multiple ...breast and lung cancer, for these ... See full document

9

ColoFinder: a prognostic 9-gene signature improves prognosis for 871 stage II and III colorectal cancer patients

ColoFinder: a prognostic 9-gene signature improves prognosis for 871 stage II and III colorectal cancer patients

... rate and is still lacking an effective ...II and III CRC samples were collected from six gene expression ...9-gene signature based Random Survival Forest (RSF) prognosis model. ... See full document

15

Prognostic Fifteen-Gene Signature for Early Stage Pancreatic Ductal Adenocarcinoma.

Prognostic Fifteen-Gene Signature for Early Stage Pancreatic Ductal Adenocarcinoma.

... outcomes of patients treated with surgery for early stage pancreatic ductal adenocarci- noma (PDAC) are variable with median survival ranging from 6 months to more than 5 ...a prognostic gene ... See full document

17

Gene expression pro filing analysis of lung adenocarcinoma

Gene expression pro filing analysis of lung adenocarcinoma

... to lung adenocarcinoma, with the aim of further understanding disease ...20 lung adenocarcinoma and 19 adjacent normal tissue samples from 10 patients with lung ... See full document

11

Erythropoietin receptor expression is a potential prognostic factor in human lung adenocarcinoma.

Erythropoietin receptor expression is a potential prognostic factor in human lung adenocarcinoma.

... mRNA of the samples and the cell lines were extracted by TRI Reagent ...μl of total RNA were reverse transcribed from each samples using deoxy-NTPs, a mixture of random primer and ... See full document

9

CREB targets define the gene expression signature of malignancies having reduced levels of the tumor suppressor tristetraprolin.

CREB targets define the gene expression signature of malignancies having reduced levels of the tumor suppressor tristetraprolin.

... the development and disables the maintenance of MYC- driven ...levels of TTP, suggesting that it may function as a tumor suppressor in several ...cancer, lung adenocarcinoma, ... See full document

24

Situation and development of worldwide agri-environment: Agricultural land uses, fertilizers consumption and carbon dioxide equivalent emissions

Situation and development of worldwide agri-environment: Agricultural land uses, fertilizers consumption and carbon dioxide equivalent emissions

... data of ten major countries in the world, Australia, Brazil, Canada, China, France, Germany, India, Japan, UK, and USA were collected from FAOSTAT ...(1000ha), and permanent meadows and ... See full document

8

A network-based gene expression signature informs prognosis and treatment for colorectal cancer patients.

A network-based gene expression signature informs prognosis and treatment for colorectal cancer patients.

... cancer signature genes are more likely to be close to known oncogenes and tumor suppressors in a protein-protein interaction ...genes of potential mechanistic importance to the CRC re- currence ...to ... See full document

13

Association between DNMT3A mutations and prognosis of adults with de novo acute myeloid leukemia: a systematic review and meta-analysis.

Association between DNMT3A mutations and prognosis of adults with de novo acute myeloid leukemia: a systematic review and meta-analysis.

... group of heterogeneous diseases with respect to biological and clinical outcomes, which have been considered to be related to cytogenetic and gene lesions in hematopoietic stem or progenitor ... See full document

11

Design And Construction Of 300W Audio Power Amplifier For Classroom

Design And Construction Of 300W Audio Power Amplifier For Classroom

... design and construction of 300W audio power amplifier for ...construction of this amplifier, microphone preamplifier, tone preamplifier, equalizer, line amplifier, output power amplifier and ... See full document

5

Protein signature of lung cancer tissues.

Protein signature of lung cancer tissues.

... Ten of the potential NSCLC biomarkers we identified are associated with growth and metabolism ...Half of these biomarkers are involved in the complex hormonal regulation of cellular growth ... See full document

15

Dissertação para obtenção do Grau de Mestre em Genética Molecular e Biomedicina Orientadora: Maria Alexandra Núncio de Carvalho Ramos Fernandes, Professora Doutora, FCTUNL Co-orientador: Pedro Miguel Ribeiro Viana Baptista, Professor associado com agregaç

Dissertação para obtenção do Grau de Mestre em Genética Molecular e Biomedicina Orientadora: Maria Alexandra Núncio de Carvalho Ramos Fernandes, Professora Doutora, FCTUNL Co-orientador: Pedro Miguel Ribeiro Viana Baptista, Professor associado com agregaç

... intensity of BSA gradually decreased when the concentrations of TS262 or TS265 increased, it was confirmed that the compounds act as quenchers and exists the interaction between them and the ... See full document

79

WP 105 Family Planning and Development: Aggregate Effects of Contraceptive Use

WP 105 Family Planning and Development: Aggregate Effects of Contraceptive Use

... realized and wanted fertility is about 2 children for parents with a primary degree (8 years of schooling) and ...(levels and heterogene- ity) and fertility gap observed in the ... See full document

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