[PDF] Top 20 Effects of melatonin on DNA damage induced by cyclophosphamide in rats

... drops of blood were collected from the animals’ tails 24 and 48 h after CP treatment (50 ...microliters of cell/heparin mixture was then embedded in 93 mL LMP agarose ...used in the comet ... See full document

... found in large amounts in citric ...biological effects on human body, including antioxidant action and insulin-sensitizing activity (Li and Schluesener ...antioxidant of human plasma ... See full document

... role in the cellular system of defense against R[LGDWLYHGDPDJH7KHGHFUHDVHLQWLVVXH*6+OHY- els after whole body irradiation may be due to its consumption during the oxidative stress induced ... See full document

... induction of inhalation general anesthesia with an isoflurane vaporizer at 3-5%, administrated through a ...placed on a warm surgical table in the supine position, and their rear paw reflexes were ... See full document

... analyzed DNA damage induced by phycocya- nin (PHY) in the presence of visible light (VL) using a set of repair endonucleases purified from Escherichia ...profile of ... See full document

... approved by the local Ethics Committee for animal studies and con- ducted at Ankara University Faculty of ...performed on male Wistar rats weighing 250-300 ...(lights on from 8:00 am to ... See full document

... Purpose: Cyclophosphamide (CYP) is an antineoplastic agent used for the treatment of many neoplastic and inflammatory ...immunomodulatory) effects. The purpose of the study was to investigate ... See full document

... genetic damage in the blood and brains cells of male rats (16), indicating that lack of sleep leads to severe molecular damage ...(19). In humans, the shortening of ... See full document

... difference in mechanisms is not fully ...(cardiotoxic) effects of DOX, in fact, they share common effectors such as oxidative stress and both involve ...2 On the other side, it has been ... See full document

... potential of GSH depletion for the toxicity of physical and chemical agents (reviewed in ...focusing on its toxicity in cultured mammalian cells depleted of ...percent of ... See full document

... The rats were anesthetised with xylazine hydrochloride 10 mg/kg (Rompun, Bayer- Istanbul) and ketamine 50 mg/kg (Ketalar, Pfizer Pharma Istanbul) intramuscularly under sterile ...incision by opening the ... See full document

... used in folk medicine for phytotherapeutic properties. The extracts of medicinal plants are known to possess cytotoxic and chemopreventative ...compounds. In this study we investigated antibacterial, ... See full document

... role in anti-inflammation and organ ...effect of propofol on heat-stress-induced cell ...caused by heat stress, LPS, or a combination of heat stress and ...role of ... See full document

... the rats were randomly divided into 2 groups of 8 rats each: (I) water control and (II) sucrose ...libitum in drinking water. The initial concentration dose of sucrose was based ... See full document

... striction induced undernutrition and reproduced in the animal model their major metabolic disor- ders, such as excessive weight loss and changes in growth and in cell/tissue differentiation, ... See full document

... the effects of brown flaxseed supplementation in natura on the prevention of DNA damage induced by 1,2-dimethylhydrazine (DMH) in ...protocols ... See full document

... production of free radicals that can impair bone healing. Melatonin is a hormone secreted mainly by the pineal gland, which participates in the neutralization process of free ...aim ... See full document

... compound of N, N-bis (2-chloroethyl) tetrahydro-2H-1,3,2- oxazaphosphorin 2-amine 2-oxide, is widely used in the treatment of autoimmune diseases such as systemic lupus erythematosus and rheumatoid ... See full document

... impairment of its function by ionizing radiation, which can occur after irradiation of one or both kidneys ...occurs in proportion to the radiation dose and volume of renal tissues ... See full document

... spontaneous DNA diffusion and also by severe centrilobular liver ...increased DNA migration observed 4 h after DEN treatment was likely a sum of genotoxicity and cytotoxicity induced ... See full document