[PDF] Top 20 Gene Expression Regulation by Agonist-Independent Constitutive Signaling of Melanocortin-1 Receptor
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Gene Expression Regulation by Agonist-Independent Constitutive Signaling of Melanocortin-1 Receptor
... whose expression levels were up- and down-regulated, respectively, by more than ...data by RT-PCR on a subset of genes down-regulated by WT-Mc1r ...down-regulation of ... See full document
6
T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression.
... whether signaling via LAT is essential for the tonic suppression of RAG-1 ...ylation of conserved tyrosines in LAT (Figure 3A) is required for the recruitment of downstream ... See full document
17
Crosstalk between thyroid hormone receptor and liver X receptor in the regulation of selective Alzheimer's disease indicator-1 gene expression.
... artificial agonist of LXR, TO901317 (TO), reduces b-amyloid accumulation and AD- specific pathological changes in the brain of an AD model mouse ...Seladin-1 gene promoter, another ... See full document
13
Regulation of Constitutive GPR3 Signaling and Surface Localization by GRK2 and β-arrestin-2 Overexpression in HEK293 Cells.
... cells of similar intensity were selected for all ...levels of cAMP (,19 m M) compared to cells transfected with pcDNA ...GPR3 expression is ...overexpression of Dyn WT increases GPR3 ... See full document
13
The melatonin agonist ramelteon induces duration-dependent clock gene expression through cAMP signaling in pancreatic INS-1 β-cells.
... evidence of the duration-dependent effects of melatonin agonists on clock gene expression in a pancreatic b-cell line (INS-1 ...mRNA expression significantly decreased after 2 h ... See full document
12
A20 is critical for the induction of Pam3CSK4-tolerance in monocytic THP-1 cells.
... Toll-like receptor (TLR)-induced immune response, and play important roles in the induction of lipopolysacchride ...pre-treatment of THP-1 cells with Pam3CSK4 down-regulated the induction ... See full document
10
ISSN 1414-431X BIOMEDICAL SCIENCES
... opioid regulation of pain and a potential site for behavioral selection in ...activity of opioid receptor ...effects of the peripheral injection of the kappa-opioid ... See full document
7
ATP8B1 gene expression is driven by a housekeeping-like promoter independent of bile acids and farnesoid X receptor.
... view of the complex structure of the ATP8B1 gene and its highly variable mRNA levels across cell types, RNA stability and post-transcriptional control appears to be more important in ATP8B1 ... See full document
10
Low concentrations of o,p'-DDT inhibit gene expression and prostaglandin synthesis by estrogen receptor-independent mechanism in rat ovarian cells.
... mechanism(s) of o,p’-DDT at levels equal to or lower than current exposure levels in ...cultures of rat ovarian granulosa cells, we determined that very low doses of o,p’-DDT (10 212 210 28 M) ... See full document
10
Regulation of Adipogenesis and Key Adipogenic Gene Expression by 1, 25-Dihydroxyvitamin D in 3T3-L1 Cells.
... series of gene expression events and activation of a number of key signaling path- ways ...induction of CCAAT/enhancer—binding protein β and δ (C/EBPβ and ...the ... See full document
29
Genes Regulating Maternal Recognition of Pregnancy in Domestic Animals: an Update
... member of aldo-keto reductase (AKR) superfamily based on the substrate specificity, molecular weight and amino acid ...consists of monomeric NAD(P)H dependent oxido-reductase with broad specifity of ... See full document
10
POST-TRANSCRIPTIONAL REGULATION OF HFE GENE EXPRESSION
... levels of normal with NMD-deficient cells, by genome-wide RNA microarray expression profile studies, revealed that the expression of approximately 10% of the human transcriptome ... See full document
160
The prima donna of epigenetics: the regulation of gene expression by DNA methylation
... effect of DNA hypomethylation is gene activation. As a matter of fact, H-RAS, C-MYC, CT genes (genes normally expressed in the tes- tis and aberrantly activated in tumors), MAGE in melanoma and CAGE ... See full document
11
Transcriptional regulation of BMP2 expression by the PTH-CREB signaling pathway in osteoblasts.
... controlled by phosphorylation through multiple signaling pathways, including the PTH signaling pathway ...effects of manipulating the signaling activity of the ... See full document
12
ATP induces NO production in hippocampal neurons by P2X(7) receptor activation independent of glutamate signaling.
... feature of this communication deals with the hypothesis that ATP induces NO production in the hippocampus through a non-NMDAR-dependent ...independence of the ATP-induced NO synthesis from NMDAR activity, ... See full document
7
A plasmid-based Escherichia coli gene expression system with cell-to-cell variation below the extrinsic noise limit
... protein expression sys- tems with low cell-to-cell variability (noise) and expression levels precisely tunable across a useful dynamic ...biology of micro- bial gene regulation, many ... See full document
15
Lymphotoxin-beta receptor and RANK signaling in TEL-JAK2-induced T-cell leukemia
... roles of genetic lesions and epigenetic alterations as steps toward T-ALL development have been largely appreciated, the various aspects on the impact of the microenvironment have been mostly ...composed ... See full document
198
Pim-1 kinase inhibits the activation of reporter gene expression in Elk-1 and c-Fos reporting systems but not the endogenous gene expression: an artifact of the reporter gene assay by transient co-transfection
... conditioned by the WEHI-3B cell line (a convenient source of ...fection of HeLa, COS7 and Jurkat cells was done by SuperFect (QIAGEN, Valencia, CA, USA) and electroporation methods, respec- ... See full document
8
Differential regulation of cysteinyl leukotriene receptor signaling by protein kinase C in human mast cells.
... which of the PKC isoforms mediate cys-LT signaling responses, we first characterized the expression of different isoforms of PKCs in MCs including classical PKCs (a, bI, bII, c), novel ... See full document
8
Osteoblast-specific transcription factor Osterix increases vitamin D receptor gene expression in osteoblasts.
... VDR gene expression. To test whether this is a direct effect of Osx on the VDR promoter, we generated a luciferase reporter construct driven by 1 kb of 59- flanking sequence from ... See full document
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