[PDF] Top 20 Follicular helper T cell in immunity and autoimmunity
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Follicular helper T cell in immunity and autoimmunity
... IL-21 in germinal centers of secondary lymphoid organs, provid- ing cognate help to B cells in the germinal center dynamic microenvironment, acting specially on naive B cells to induce isotype switch to IgG ... See full document
11
Full restoration of Brucella-infected dendritic cell functionality through Vγ9Vδ2 T helper type 1 crosstalk.
... Vc9Vd2 T cells as effector cells of innate immunity is well recognized [11], and several studies have been investigating the possibility of exploiting their effector properties in infections ... See full document
11
Peripheral CD4CD8 double positive T cells with a distinct helper cytokine profile are increased in rheumatoid arthritis.
... positive T cells were detectable only in ACPA positive and not in ACPA negative RA ...involvement in the autoreactive T cell help provided for auto-reactive, antibody ... See full document
10
Abortive T follicular helper development is associated with a defective humoral response in Leishmania infantum-infected macaques.
... binding and internalization of specific antigen, B cells generally depend on cognate interactions with CD4 T cells to differentiate into antibody-producing plasma cells (PCs) ...B cell can either ... See full document
17
M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A.
... tibia and the femur of WT, MyD88 2/2 and TRIF 2/2 mice (all in the Bl/6 background) with ice-cold ...blood cell lysis buffer (BioWhittaker, Wakersville, MD, USA), ...seeded in petri ... See full document
12
Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection.
... conveniently and reliably augment the Th2 cell re- sponse to further understand unappreciated elements underlying Th2-mediated ...breakdown in protective ...disease in immunosuppressed ... See full document
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Helper T cell epitope-mapping reveals MHC-peptide binding affinities that correlate with T helper cell responses to pneumococcal surface protein A.
... carriage and pneumonia will greatly benefit efforts in controlling these ...proteins and polysaccharide capsule have recently been implicated in the virulence of and protective ... See full document
16
Linking immunity and hematopoiesis by bone marrow T cell activity
... If T cells recognize the peripheral self with too much affinity and avidity they initiate a deleterious autoimmune ...if T cells are unable to recognize the periph- eral self, they cannot survive or ... See full document
12
Altered Memory Circulating T Follicular Helper-B Cell Interaction in Early Acute HIV Infection.
... Total and HIV-specific IgG was measured by ELISA on culture supernatant and plasma as pre- viously described ...1μg/mL in phosphate buffered saline (PBS) overnight at ...20), and subsequently ... See full document
17
HIV-1 infection on Follicular Helper T cells
... mechanisms and cells (macrophages, DCs and natural killer cells (NKs)) that provide immediate protection against ...physical and chemical barriers, such as skin and tears, and by ... See full document
69
Novel strategies to enhance vaccine immunity against coccidioidomycosis.
... downregulated in BALB/c mice, the outcome could be ...(APCs) and promotes cellular ...(MW) and dendritic cells (DC) but not neutrophils ...hydration and dilation steps physically fractured the ... See full document
4
Attenuation of antigen-specific T helper 1 immunity by Neolitsea hiiranensis and its derived terpenoids
... distributed in the genus Neolitsea. They were also found in large amounts in the curry, cloves, cinnamon, black pepper, cannabis, guava, and ...tumor cell lines with IC 50 values of ... See full document
27
Autoimmunity and molecular mimicry in tropical spastic paraparesishuman T-lymphotropic virus-associated myelopathy
... ies in all Colombian TSP/HAM patients tested ...patients and en- dothelial cells of the brain (23) showed that circulation of these autoantibodies in blood is part of the progression not only of TSP/ ... See full document
10
CD8(+) T Cell-Mediated Immunity during Trypanosoma cruzi Infection: A Path for Vaccine Development?
... host cell, T. cruzi escapes from the parasitophorous vacuole and enters the cytosol, where it diferentiates into amastigotes and begins its ...is in the cytosol, its secreted antigens ... See full document
13
Specific humoral immunity versus polyclonal B cell activation in Trypanosoma cruzi infection of susceptible and resistant mice.
... B cell activation that leads to hypergammaglobulin- emia and delayed specific humoral immune response is generally accepted as a characteristic of acute phase Chagas disease in humans and is ... See full document
16
Influenza nucleoprotein delivered with aluminium salts protects mice from an influenza A virus that expresses an altered nucleoprotein sequence.
... variants and newly emergent potentially pandemic ...safe and effective adjuvant that can be used in individuals of all ...challenge in mice vaccinated with the nucleoprotein from the PR8 ... See full document
12
mTOR Inhibition Attenuates Dextran Sulfate Sodium-Induced Colitis by Suppressing T Cell Proliferation and Balancing TH1/TH17/Treg Profile.
... mTOR-deficient T cells were unable to differentiate into TH1, TH2, or TH17 effector cells while they displayed normal activation and IL-2 production upon initial stimulation ...activation, T cells ... See full document
19
SPECTRUM OF THYROID LESIONS-HISTOMORPHOLOGICAL PATTERNS - EXPERIENCE AT A TERTIARY CARE CENTRE
... Thyroid gland is unique among endocrine organs. Thyroid tumours are the most common endocrine tumours which affect females more frequently at age range of 30-60 years most of which are benign. Malignant neoplasms of ... See full document
5
Tissue inhibitor of metalloproteinase 1 is preferentially expressed in Th1 and Th17 T-helper cell subsets and is a direct STAT target gene.
... result in the generation of distinct subsets, which are defined by the cytokines they preferentially express ...Differentiated helper T (Th) cells are central players in the adaptive immune ... See full document
9
Arq. NeuroPsiquiatr. vol.47 número1
... This finding results from the fact that Cy-A preferentially inhibits the activity of T-helper cell lymphocytes and the receptor of interleukin-2, spares a population of suppression whi[r] ... See full document
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