[PDF] Top 20 Identification and Manipulation of Cystatins to Control Mycobacterium tuberculosis Infection of Human Macrophages
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Identification and Manipulation of Cystatins to Control Mycobacterium tuberculosis Infection of Human Macrophages
... A capacidade adaptativa do M. tuberculosis levou à aquisição de mecanismo que contornam os mecanismos de defesa do hospedeiro. O sistema imunitário responde ao contacto pelos microrganismos, iniciando-se o ... See full document
45
Pre-exposure of Mycobacterium tuberculosis-infected macrophages to crystalline silica impairs control of bacterial growth by deregulating the balance between apoptosis and necrosis.
... RPMI-1640 and vortexed prior to dilution with the respective medium to reach the final ...exposed to CS for 24 h at the following concentrations: 1, 5 and 10 ...medium and then ... See full document
13
Differential MicroRNA Expression in Human Macrophages with Mycobacterium tuberculosis Infection of Beijing/W and Non-Beijing/W Strain Types.
... Prince of Wales Hospital, Hong ...years and gave written informed ...4), and the active TB patients (n = 3), whole blood specimens were collected for monocytes ...smear and culture. Active TB ... See full document
16
Predicting and analyzing interactions between Mycobacterium tuberculosis and its human host.
... Interolog-HPI-array and Interolog-DIP-array ...85 human proteins and 53 Mtb ...subnetwork of 61 ...The human proteins NFKB1 and CD74 are connected to 10 and 5 Mtb ... See full document
12
Uptake and accumulation of oxidized low-density lipoprotein during Mycobacterium tuberculosis infection in guinea pigs.
... accumulation of OxLDL, we also show that two OxLDL receptors, CD36 and LOX1 show increased expression over the course of ...uptake of M. tuberculosis by macrophages ...shown ... See full document
10
Identification and Characterization of Lipase Activity and Immunogenicity of LipL from Mycobacterium tuberculosis.
... Lipids and esterases/lipases associated with lipid metabolism are very important in the mycobacterial life ...percent of the M. tuberculosis genome encodes products that participate in lipid ... See full document
20
Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages.
... opportunity to decipher host pathogen cross-talk on the global ...able to investigate gene expression changes in both Mycobacterium tuberculosis , a major human pathogen, and its ... See full document
14
Mycobacteria manipulation of host proteases and inflammatory pathways during infection within human macrophages and dendritic cells
... concerning human macrophages, we found that infection of these cells with ...M. tuberculosis H37Rv decreases basal cathepsin B protein levels, while infection with the non- ... See full document
58
The endothelin system has a significant role in the pathogenesis and progression of Mycobacterium tuberculosis infection
... insets, and 5) and a tendency for higher numbers of CFU and larger lesions ( ...M. tuberculosis infection only in wild-type mice ( ...infiltration of neutrophils into ... See full document
12
Exogenous Re-infection by Multiple Exposures to <i>Mycobacterium tuberculosis</i> Contributes to Subsequent Development of Active Tuberculosis
... majority of tuberculosis (TB) exists in the world’s poorest countries, where costly biosafety level three facilities for containment of infectious TB patients and diagnostic facilities are not ... See full document
6
Proteases associated with mycobacterium tuberculosis infection
... One of the host’s key responses to contain the bacillus during infection is the formation of a granuloma, which when intact becomes beneficial as it keeps the pathogen under control ... See full document
12
Validation of a real-time PCR assay for the molecular identification of Mycobacterium tuberculosis
... goal of diagnos- ing the bacillus M. tuberculosis in bacterial suspension ...number of positive and negative samples shows that it provides repeatability, reproduci- bility and ... See full document
7
EVALUATION OF METHODS FOR DETECTION AND IDENTIFICATION OF MYCOBACTERIUM SPECIES IN PATIENTS SUSPECTED OF HAVING PULMONARY TUBERCULOSIS
... diagnosis of TB is routinely based on baciloscopy results (4), but in specific cases, cultures are performed at some of the few Central Laboratories of Public Health, leading to long delays in ... See full document
6
Interference of mycobacterium tuberculosis with the endocytic/ antigen presentation pathways on macrophages and dendritic cells
... assigned to the new order of Corynebacteriales (Goodfellow, ...majority of the 150 species that comprise this genus are non-pathogenic environmental bacteria that possess striking similarities with ... See full document
270
Manipulation of cysteine cathepsins during Mycobacterium tubersulosis infection of human macrophages
... consumption, and the “white plague”, has tormented humanity for thousands of years; the oldest record of tuberculosis infecting human beings dates back to approximately 9000 ... See full document
43
Type-2 diabetes alters the basal phenotype of human macrophages and diminishes their capacity to respond, internalise, and control Mycobacterium tuberculosis
... characteristic of patients with ...production of TNF-α, IL-6, and MCP-1 in response to different Mycobacterium species by MFs isolated from mice with diabetes (Alim et ...production ... See full document
11
Identification and characterization of host cathepsins and cystatins during tuberculosis and HIV co-infection of antigen presenting cells
... mono-infection of macrophages. RNA from non-infected, Msm and Mtb infected Mϕ was extracted and quantified by real-time reverse transcriptase PCR at 1, 4 and 24 h ... See full document
69
Human factors required for mycobacterium tuberculosis macrophage infection
... M. tuberculosis can survive and even grow within macrophages, within phagosomes, a cellular compartment that provides camouflage from the immune system and limits the access and ... See full document
206
Analysis of Mycobacterium tuberculosis-specific CD8 T-cells in patients with active tuberculosis and in individuals with latent infection.
... HLA-A*0201 and human b2-microglobulin, produced in Escherichia coli, were solubilized in urea and injected together with each synthetic peptide into a refolding buffer consisting of 100 mM ... See full document
10
Mycobacterium sherrisii lung infection in a brazilian patient with silicosis and a history of pulmonary tuberculosis
... pulmonary tuberculosis with rifampin, isoniazid, pyrazinamide, and ethambutol was started due to worsening of respiratory status, and the finding of acid-fast bacilli in ... See full document
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