[PDF] Top 20 Modulation of NMDA receptor activity through adenosine A2A receptors in the hippocampus
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Modulation of NMDA receptor activity through adenosine A2A receptors in the hippocampus
... limitations in this project that did not allow the increase in number of experiments using this ...increase the number of experiments, replicating all the procedure and ... See full document
83
Stress-induced changes of hippocampal NMDA receptors: modulation by duloxetine treatment.
... Antidepressant activity may therefore originate directly from the reduced function of NMDA receptors, as indicated by our data as well as by previous work that investigated ... See full document
8
Activation of adenosine A2A receptor facilitates brain-derived neurotrophic factor modulation of synaptic
... role in protecting mature neurons from neuronal atrophy in the de- generating human ...decrease in BDNF levels might be involved in neurodegenerative disorders such as Alzheimer’s dis- ... See full document
9
Tonic activation of A2A adenosine receptors unmasks, and of A1 receptors prevents, a facilitatory action of calcitonin gene-related peptide in the rat hippocampus
... underestimation of the CGRP responses due to desensitization (see Aiyar et ...concentration of CGRP was applied to each slice, and thus, the concentration response curves showed in this ... See full document
7
MARK/Par1 Kinase Is Activated Downstream of NMDA Receptors through a PKA-Dependent Mechanism.
... Since the activation of NMDA receptor is essential for synaptic plasticity, our results raise the exciting possibility that NMDA receptor-mediated Par1 activation is ... See full document
11
Relationship between the adenosine A1 receptor and cGMP levels in the hippocampus: implications on neurotransmission and synaptic plasticity
... disease of the central nervous system (Calabresi 2004). It attacks the myelinated axons in the CNS, destroying the myelin and the axons to varying degrees (Weinshenker ... See full document
141
A1 and A2A Adenosine receptors expression in ALS transgenic mice for the human gene SOD1
... features of ALS. Aspects of toxicity can arise either through aberrant chemistry, mediated by the misfolded aggregated mutants, or through loss or sequestration of essential ... See full document
57
Setting GABA levels : GABA transporters modulation by adenosine receptors
... option in epilepsy is to increase the inhibitory tone in order to prevent ...achieved through the blockade of GABA uptake or by the reversal of GABA ... See full document
249
Adenosine A2A receptor modulation of hippocampal CA3-CA1 synapse plasticity during associative learning in behaving mice
... insertion in the lid. During the same surgical step, animals were also implanted with bipolar-stimulating electrodes in the right Schaffer collateral pathway of the dorsal ... See full document
10
Role of adenosine A2A receptors in the neuroprotective effect of corticotrophin releasing hormone (CRH)
... minimum of 20 µM which is in accordance with previous results (Choi et ...With the lowest glutamate concentrations, cells present a high rate of pro- caspase-3 fragmentation, an apoptotic ... See full document
65
Nitric oxide modulates blood pressure through NMDA receptors in the rostral ventrolateral medulla of conscious rats
... tested the role of NO on the cardiovascular re- sponse caused by the activation of two types of glutamatergic receptors, NMDA and AMPA ...that the blockade ... See full document
9
The role of cGMP on adenosine A1 receptor-mediated inhibition of synaptic transmission at the hippocampus
... by the action of guanylyl cyclases (GC), which are a family of enzymes that catalyse the conversion of GTP to ...types of GC, the soluble form (sGC) activated by nitric ... See full document
65
Contribuition of different cellular subsets to the adenosine A2a receptor overexpression in the rat brain
... produced through the catabolism of ATP by ...present in all cell types, its ability to modulate cell metabolism is widely described, namely in Central Nervous System (CNS), where it is ... See full document
77
Arginine 199 and leucine 208 have key roles in the control of adenosine A2A receptor signalling function.
... profiles of the Wild-Type and Rag23 receptors The activity of each of the receptor constructs is summarised in Table ...1. The numerical data ... See full document
10
Enhanced role of adenosine A2A receptors in the modulation of LTP in the rat hippocampus upon ageing
... adenosine receptor knockout mouse and the antibody against vGluT1 did not label any element labelled by markers of GABAergic, cholinergic or dopaminergic markers in hippocampal nerve ... See full document
10
Adenosine A2A receptors in the rat hippocampus: stress related changes
... death. In situations of acute stress this is reversible (Sousa et ...if the corticosterone levels in the bloodstream increase chronically, as in MS animals (Lopes, 2008), a ... See full document
63
The Role of Hippocampal NMDA Receptors in Long-Term Emotional Responses following Muscarinic Receptor Activation.
... involvement of NMDAR signaling on behavioral long-term anxiety induced by pilocar- pine comprises a substantial progress regarding the mechanisms underlying these ...overexpression in the ... See full document
18
Subcellular localization of adenosine A2a receptors in hippocampal synapses
... A1R, adenosine A2A receptors (A2AR) show a more restricted distribution, being characteristic of dopamine enriched areas and highly expressed in the striato- pallidal GABAergic ... See full document
69
Modulation of glutamat AMPA receptors by adenosine, in physiological and hypoxic/ischemic conditions
... types of cation channels, such as inwardly rectifying potassium channels and NMDA receptors (reviewed by Williams, ...1997). In fact, intracellular spermine contributes to intrinsic gating and ... See full document
239
Characterization of the levels and G-protein coupling of adenosine A2A receptors in hippocampus and striatum of transgenic rats overexpressing adenosine A2A receptors in the brain
... and the risk for development of Parkinson Disease (Ascherio et ...consumption, the effects exerted in the brain by caffeine depend on its ability to block adenosine A1 and ... See full document
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