[PDF] Top 20 Role of myotonic dystrophy protein kinase (DMPK) in glucose homeostasis and muscle insulin action.
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Role of myotonic dystrophy protein kinase (DMPK) in glucose homeostasis and muscle insulin action.
... disease and a major international public health ...combination of genetic susceptibility and other risk factors including obesity, increased age, hypertension, and lifestyle ...[1]. ... See full document
11
A tail-anchored myotonic dystrophy protein kinase isoform induces perinuclear clustering of mitochondria, autophagy, and apoptosis.
... especially in heart and skeletal muscle, showed disorga- nized cristae structure and symptoms like reduced workload tolerance, atrophy, hypertrophic cardiomyopathy, myotonic myopathy ... See full document
12
Palmitate-activated macrophages confer insulin resistance to muscle cells by a mechanism involving protein kinase C θ and ε.
... PKCh and PKCe involvement in insulin resistance in vivo PKCh and PKCe have emerged as strong candidates for mediating lipid-induced insulin ...resistance. In mice, PKCh ... See full document
16
Regulation of glucose homeostasis by KSR1 and MARK2.
... KSR1 in the cytoplasm, away from the MAP kinase pathway ...an in vitro kinase assay was ...KSR1 in the presence of ATP, phosphorylation of Ser392 was detectable with a ... See full document
8
Magnetic resonance imaging of masticatory muscles and temporomandibular joint in myotonic dystrophy patients (Steinert's disease)
... crises of the complex partial type prevailed (88.2%) and the neurological exam was normal in ...67.7% of all patients. M agnetic resonance image show ed the tumors in all cases, w hile ... See full document
4
The PICALM protein plays a key role in iron homeostasis and cell proliferation.
... (PICALM) protein associates with the plasma membrane, binds clathrin, and plays a role in clathrin-mediated ...Alterations of the human PICALM gene are present in aggressive ... See full document
14
Activation of AMP-Activated Protein Kinase and Stimulation of Energy Metabolism by Acetic Acid in L6 Myotube Cells.
... heterotrimeric protein kinase, has been found to play a key role in regulation of whole-body energy balance by phosphorylating key metabolic enzymes in both biosynthetic ... See full document
19
The role of business intelligence in decision process modeling
... case of web ...ment and coordination of business processes and it becomes a valuable and suitable source of data about ...seen in (Draker, 2003). However, multiple formats ... See full document
9
Improved Muscle Function in Duchenne Muscular Dystrophy through L-Arginine and Metformin: An Investigator-Initiated, Open-Label, Single-Center, Proof-Of-Concept-Study.
... muscular dystrophy (DMD) is an X-linked recessive neuromuscular disorder that affects 1 in ...rapid and irreversible replacement of normal muscle by connective tissue and ... See full document
19
Rev. bras. cineantropom. desempenho hum. vol.16 número5
... prevalence of obesity and diabetes mellitus has increased signiicantly in recent years and the knowledge that adipose tissue has endocrine activity and plays impor- tant roles in ... See full document
8
Blood glucose and insulin levels in patients with peripheral vestibular disease
... prevalence of glucose and glucose-insulin alterations in patients with peripheral vestibular disorders by studying the four-hour glucose-insulin curve; to check at ... See full document
5
Insulin Action in Peripheral Glucose Uptake - The Molecular Perspective Acção Periférica da Insulina na Captação de Glucose – a Perspectiva Molecular
... central role in carbohy- drate metabolism. Although insulin presents different effects in different target-organs, one can consider that its major role in extra- hepatic tissues, ... See full document
9
ISSN 0100-879X BIOMEDICAL SCIENCES AND CLINICAL INVESTIGATION
... variety of liver ailments. To investigate its effect and the underlying mechanisms of action on non-alcoholic fatty liver in rats, we used 60 4-6-week-old male Sprague-Dawley rats to ... See full document
9
Pancreatic alpha-cell dysfunction contributes to the disruption of glucose homeostasis and compensatory insulin hypersecretion in glucocorticoid-treated rats.
... fasted and fed conditions. Interestingly, their insulin/glucagon ratio did not increase from the fasted state to the fed state, which may result in impaired insulin suppressive effects ... See full document
11
Einstein (São Paulo) vol.12 número2
... maintenance of glucose homeostasis is complex and involves, besides the secretion and action of insulin and glucagon, a hormonal and neural mechanism, ... See full document
3
Genetic analysis of the role of protein kinase Ctheta in platelet function and thrombus formation.
... spreading, and the surface area of platelets was measured by manually outlining each cell (approximately 25 mm 2 ...area. In both McCarty’s study and ours, mouse platelets rarely formed large ... See full document
7
Índice HOMA (homeostasis model assessment) na prática clínica: uma revisão.
... 1980’s, insulin resistance (IR) has been associated to the risk of cardiovascular disease and type 2 diabetes ...one of the methods used for IR measurement, mainly in epide- miological ... See full document
7
Temporal relationship between diet-induced steatosis and onset of insulin/leptin resistance in male Wistar rats.
... analysis of the main checkpoints of the respective insulin and leptin signaling path- ways showed that the occurrence of lowered insulin sensitivity was at least 2 weeks earlier ... See full document
15
Regulation of myosin light chain kinase during insulin-stimulated glucose uptake in 3T3-L1 adipocytes.
... inhibition of myosin II resulted in impaired insulin- stimulated glucose uptake in 3T3-L1 adipocytes ...IIA and IIB, it is important to determine the role of each ... See full document
12
PHYSIOTHERAPY PRACTICE IN THE NEUROMUSCULAR REHABILITATION PROCESS OF STEINERT’S MYOTONIC DYSTROPHY – CASE REPORT
... the role of the kinesiotherapy in treatment and control of the evolution of Steinert’s myotonic dystrophy, and its impact in the quality of ... See full document
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