[PDF] Top 20 The role of regulatory T cells in the control of B cell mediated immune responses
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The role of regulatory T cells in the control of B cell mediated immune responses
... Since the discovery of CD4 + CD25 + Treg cells, the concept of regulatory cells in general has increasingly gained acceptance by the scientific community and ... See full document
150
HIV-specific T-cell responses, T-cell activation and regulatory T-cells in AIDS pathogenesis : lessons from the HIV-2 model
... increase of Treg within CD4 + T-cells that we observed in ART-discordants is of interest, particularly as it appears to be preserved over ...increase in the proportion ... See full document
192
Role of the mitochondria in immune-mediated apoptotic death of the human pancreatic β cell line βLox5.
... Treatment of bLox5 cells with rhIFNc and rhTNFa resulted in activation of Caspases 8 and 3 ...these cells by multiple ...analyses of cytokine-induced bLox5 killing indicated that ... See full document
12
Immune reconstitution inflammatory syndrome and the influence of T regulatory cells: a cohort study in The Gambia.
... proliferative responses of a variety of immune cell types [18–19] in response to microbial and self-antigens ...analyzing the role of Tregs in IRIS ... See full document
8
homeostasis of the IL-2-producing CD4 T cells and theirrole in the control of T regulatory cells function and number.
... presentation, the model predicts that a large enough kick to the system is enough to drive the system into a state characterised by large numbers of effector T cells (trajectories ... See full document
174
Role of SHIP-1 in the adaptive immune responses to aeroallergen in the airway.
... regulator in a variety of cytokine, immunoreceptor, and growth factor signaling pathways in different cell types, including T cells, B cells, mast cells, ... See full document
9
Prolonged acceptance of skin grafts induced by B cells places regulatory T cells on the histopathology scene
... study the immune response of an nB cell-treated animal, 1 week after nB cell injection the animals were immunized in the footpad and 1 week later draining lymph ... See full document
7
Thymic activity and regulatory CD4+ T cells in the immune reconstitution of HIV infected individuals : two (in)dependent factors?
... increase in the peripheral blood after HAART initiation [67]. So, in the first hypothesis we could speculate that increased percentages of peripheral Tregs post HAART initiation could ... See full document
67
Immune engagement thresholds for CD8+ T CELL control of yherpesvirus-driven B CELL
... human B cells by expressing the growth programme, driving the establishment of continuously proliferating lymphoblastoid cell lines (LCLs) (Thorley-Lawson and Mann, ...1985). ... See full document
242
Elucidating the role of macrophages and CD4+CD25+ regulatory T cells on colorectal cancer cell invasion
... neoplastic cells and the surrounding host ...network of cytokines, chemokines and matrix remodelling enzymes that will dictate the tumour fate 18 .... In general, when solid tumours ... See full document
79
A novel regulatory T cell population in the gut.
... types of T cell– specific surface proteins, CD4 and CD8aa. The researchers were intrigued by these double-positive CD4CD8aa lamina propria lymphocytes (DP8a LPL) because most T ... See full document
2
Regulatory T-cell development in the human thymus
... implicated in human tTreg differentiation and/ or proliferation, namely JAK3/STAT-5, Notch, CD80/CD86, ICOS/ICOSL, CD40/CD40L, thymic stromal lymphopoietin (TSLP), as well as the common-gamma chain (γC) ... See full document
7
Antibody-independent control of gamma-herpesvirus latency via B cell induction of anti-viral T cell responses.
... components of the immune system contribute to the control of latent and persistent cHV68 ...CD8 T cells [10,21,22], CD4 T cells [21,27–29], perforin ... See full document
13
Foxp3+ regulatory T cells control persistence of viral CNS infection.
... regulatory T cells (Tregs) in autoimmune and pathogen-induced immune responses has been studied intensively during recent ...by the discovery of the ... See full document
8
Nef-specific CD8+ T cell responses contribute to HIV-1 immune control.
... studies in the SIV-macaque model of HIV infection suggest that Nef-specific CD8+ T-cell responses may mediate highly effective immune control of ...viraemia. ... See full document
10
The Role Of miRNAs In CD8+ T Cell Differentation
... for the effect of miR-132 in the immune system comes from a mouse model deficient in the miR-212/132 cluster (where miR-132 and miR-212, which are tandem miRNAs at ... See full document
87
Modulation of invariant natural killer T (INKT)-Cell function in immune-mediated diseases
... response, the key pathogenic players in multiple sclerosis were shown to be T cells producing IFN- γ and IL-17 ...(1) the adoptive transfer of Th17 cells, but not Th1 ... See full document
48
The role of the SLAMSAP signaling pathway in the modulation of CD4+ T cell responses
... modulate the immune response through the TCR interaction, while SAP regulates the activation of protein kinase C-teta, B cell lymphoma 10, NF-κB, and GATA-3 (6,50) (Figure ... See full document
8
To investigate the necessity of STRA6 upregulation in T cells during T cell immune responses.
... h of TCR stimulation. STRA6 is the high-affinity receptor for plasma retinol-binding protein (RBP) and mediates cellular vitamin A ...for T-cell activation, differentiation and ...inspection. ... See full document
13
The Role of Regulatory T Cells and TH17 Cells in Multiple Myeloma
... immunity in MM. Tregs play an important role in the preservation of self-tolerance and modulation of overall immune responses against infections and tumor ... See full document
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